Article
Environmental Sciences
Dahui Zhu, Yaxin Niu, Keke Fan, Fujun Zhang, Yu Wang, Gejiao Wang, Shixue Zheng
Summary: This study found that the selenium-oxidizing Agrobacterium sp. T3F4 strain can steadily colonize soil and plant tissues, leading to increased absorption of selenium by plants through selenium oxidation in the soil.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Chenhao Lyu, Jiawei Chen, Lei Li, Zhuqing Zhao, Xinwei Liu
Summary: This study investigated the characteristics of Se enrichment in the water-soil-plant system, as well as the dietary Se status of local residents in seleniferous areas. The results showed that Se in well water mainly came from Se-enriched shales and coals, and the mobility of Se in seleniferous soils was relatively low. The concentration of Se in edible parts of crops varied widely, with cereal plants having a higher Se-enrichment ability than tuber plants. The probable dietary Se intake in high-Se areas has decreased in recent years but still exceeds the permissible value. Reducing cereal-derived dietary Se intake is an important strategy to improve the Se nutrition status in high-Se areas.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Editorial Material
Chemistry, Multidisciplinary
Jerry Zhang, Chao Wang, Alexander J. Leothand
Summary: Chen et al. reported a zinc/selenium conversion battery with a high discharge working voltage of about 1.15 V. However, based on theoretical calculations, the discharge voltage of this battery should not exceed 0.71 V. In addition, the data presented by the author in Figures S11, S14, and S23 are inconsistent with previous reports and experimental results, raising doubts about their explanations and core conclusions. Finally, it is found that the main contribution to capacity and voltage comes from the conversion reaction between ZnSe and Se(TFSI)(4).
ENERGY & ENVIRONMENTAL SCIENCE
(2022)
Article
Food Science & Technology
Nan Chen, Changhui Zhao, Tiehua Zhang
Summary: Selenium is an essential trace element involved in the synthesis of selenoproteins in higher animals, with organic selenium considered safer than inorganic selenium. While super-nutritional intake of selenium has been claimed to prevent cancer, consistent clinical results are lacking. In selenium-deficient areas, consuming selenium-rich foods may be the safest and best recommendation.
Article
Chemistry, Multidisciplinary
Jiang Ouyang, Bo Deng, Binhua Zou, Yongjiang Li, Qingyue Bu, Yuan Tian, Mingkai Chen, Wei Chen, Na Kong, Tianfeng Chen, Wei Tao
Summary: This study developed an innovative oral hydrogel microbeads-based biochemical strategy for in situ synthesis of selenoproteins, which effectively bypassed the limitations of oral protein delivery and generated therapeutic selenoproteins. The strategy was tested in mice with inflammatory bowel disease, showing significant reduction in proinflammatory cytokine secretion, modulation of immune cells, and regulation of gut microbiota composition to relieve colitis-associated symptoms and maintain intestinal homeostasis. This in situ selenoprotein synthesis strategy has the potential to be applied to various diseases associated with intestinal immunity and microbiota.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Agriculture, Dairy & Animal Science
Luca Ferrari, Donata M. I. R. Cattaneo, Rossella Abbate, Michele Manoni, Matteo Ottoboni, Alice Luciano, Christoph von Holst, Luciano Pinotti
Summary: Selenium is an essential micronutrient that plays an important role in the development and physiological homoeostasis of animals and humans. This review discusses the role of selenium in the environment, plants, and animal bodies and explores different sources of selenium supplementation, focusing on Se-enriched yeast. Other potential sources such as Se-enriched insects and Se-nanoparticles are also examined for their use in animal nutrition. The scientific evidence suggests that sodium selenite and Se-yeast are the main options for inorganic and organic selenium supplementation, but further research is being conducted on alternative sources with high bioavailability and reduced environmental emissions.
Article
Chemistry, Multidisciplinary
Lina He, Jiating Zhao, Liming Wang, Quancheng Liu, Yuqin Fan, Bai Li, Yong-Liang Yu, Chunying Chen, Yu-Feng Li
Summary: Selenium, an essential trace element, is known for its antioxidant and immunity-boosting capabilities, which can have a strong antiviral effect. NanoSelenium shows potential in combating COVID-19, highlighting the importance of Selenium in fighting various viruses.
Review
Biotechnology & Applied Microbiology
Xinling Nie, Xurui Yang, Junyi He, Pei Liu, Hao Shi, Tao Wang, Daihui Zhang
Summary: In recent years, microbial conversion of inorganic selenium into a safe and efficient form of organic selenium has been a focus of research. Selenium nanoparticles derived from nanotechnology offer higher safety, absorption, and biological activity compared to other selenium forms. This paper reviews the conversion of inorganic selenium to less toxic organic selenium and the biosynthesis of selenium nanoparticles by microbes. The synthesis method, potential mechanism, and characterization of selenium in different forms are also discussed.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Elena G. Varlamova, Egor A. Turovsky, Ekaterina V. Blinova
Summary: The review highlights the importance of selenium nanoparticles in human health and medicine, detailing their production methods and the potential for creating new drugs or enhancing existing ones. Selenium, a key component in antioxidant enzymes, has been extensively studied in recent years, with a focus on its potential applications in medicine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Michael V. Goltyaev, Elena G. Varlamova
Summary: The liver, as the largest gland in the body, plays a crucial role in regulating physiological processes. Nanomedicine using nanoparticles, especially selenium nanoparticles, has gained popularity in the treatment and diagnosis of liver diseases due to their environmentally safe, low-cost, simple, and high-performance properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biotechnology & Applied Microbiology
Ying Liu, Sebastian Hedwig, Andreas Schaeffer, Markus Lenz, Mathieu Martinez
Summary: Selenium (Se) deficiency affects millions of people globally, and the volatilization of Se to the atmosphere may hinder its entry into the food chain. Laboratory experiments have shown that the sulfur (S) status of bacteria plays a crucial role in determining the amount of Se volatilized, shedding light on the fluxes of Se in the environment.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Review
Nutrition & Dietetics
Ying Sun, Zhineng Wang, Pin Gong, Wenbo Yao, Qian Ba, Hui Wang
Summary: Selenium is an important micronutrient involved in various biological processes, and its deficiency can increase the risk of HIV infection, cancer, cardiovascular disease, and inflammatory bowel disease. Selenium has antioxidant, anticancer, immunomodulatory, hypoglycemic, and intestinal microbiota-regulating properties. The relationship between selenium status and health effects is U-shaped, and individuals with low baseline selenium levels may benefit from supplementation, while those with acceptable or high selenium levels may face potential health hazards. Selenium supplementation is beneficial in various populations and conditions, but its safety is still a subject of debate due to the narrow safety window.
FRONTIERS IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Wenli Hu, Chong Zhao, Hongbo Hu, Shutao Yin
Summary: Selenium is an essential micronutrient for mammals, with deficiency posing a serious threat to health. Biofortification strategies have been developed to combat selenium deficiency. While selenium supplementation is beneficial for preventing and treating chronic diseases, the effects may vary depending on individual baseline selenium status.
Article
Biochemical Research Methods
Milan Zizic, Marina Stanic, Giuliana Aquilanti, Danica Bajuk-Bogdanovic, Goran Brankovic, Ivanka Rodic, Miroslav Zivic, Joanna Zakrzewska
Summary: The biotransformation of toxic selenium ions into non-toxic species has been a focus of research in biofortification and production of selenium nanoparticles (SeNPs), with less attention given to the mechanisms of transformation. In this study, a combination of analytical techniques was used to characterize SeNPs and monitor selenium transformation in the fungus Phycomyces blakesleeanus. The results showed the formation of SeNPs and volatile methylated selenium compounds after only a few hours of incubation. Different structural forms of elemental selenium were also detected.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Aleksandra Sentkowska, Krystyna Pyrzynska
Summary: This study describes the green synthesis of selenium nanoparticles (SeNPs) using different types of tea, which exhibited high antioxidant properties and the ability to neutralize hydroxyl radicals. However, the purification of the nanoparticles remains a challenge.
Review
Cardiac & Cardiovascular Systems
Sandeep Prabhu, Aleksandr Voskoboinik, David M. Kaye, Peter M. Kistler
HEART LUNG AND CIRCULATION
(2017)
Article
Cardiac & Cardiovascular Systems
Sandeep Prabhu, Aleksandr Voskoboinik, Alex J. A. McLellan, Kah Y. Peck, Bhupesh Pathik, Chrishan J. Nalliah, Geoff R. Wong, Sonia M. Azzopardi, Geoffrey Lee, Justin Mariani, Liang-Han Ling, Andrew J. Taylor, Jonathan M. Kalman, Peter M. Kistler
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2017)
Letter
Cardiac & Cardiovascular Systems
Sandeep Prabhu, Peter M. Kistler
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2017)
Article
Cardiac & Cardiovascular Systems
Hariharan Sugumar, Stuart P. Thomas, Sandeep Prabhu, Aleksandr Voskoboinik, Peter M. Kistler
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2018)
Article
Cardiac & Cardiovascular Systems
Sandeep Prabhu, Manish Kalla, Kah Y. Peck, Aleksandr Voskoboinik, Alex J. A. McLellan, Bupesh Pathik, Chrishan J. Nalliah, Geoff R. Wong, Hariharan Sugumar, Sonia M. Azzopardi, Geoffrey Lee, Liang-Han Ling, Jonathan M. Kalman, Peter M. Kistler
Article
Cardiac & Cardiovascular Systems
Aleksandr Voskoboinik, Jeremy Moskovitch, George Plunkett, Jason Bloom, Geoffrey Wong, Chrishan Nalliah, Sandeep Prabhu, Hariharan Sugumar, Ramanathan Paramasweran, Alex McLellan, Liang-Han Ling, Cheng-Yee Goh, Samer Noaman, Himawan Fernando, Michael Wong, Andrew J. Taylor, Jonathan M. Kalman, Peter M. Kistler
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Hariharan Sugumar, Shane Nanayakkara, David Chieng, Geoffrey R. Wong, Ramanathan Parameswaran, Robert D. Anderson, Ahmed Al-Kaisey, Chrishan J. Nalliah, Sonia Azzopardi, Sandeep Prabhu, Aleksandr Voskoboinik, Geoffrey Lee, Alex J. McLellan, Liang-Han Ling, Joseph B. Morton, Jonathan M. Kalman, Peter M. Kistler
Article
Cardiac & Cardiovascular Systems
David Chieng, Anandaroop Lahiri, Hariharan Sugumar, Ahmed Al-Kaisey, Ramanathan Parameswaran, Robert D. Anderson, Sandeep Prabhu, Liang-Han Ling, Joseph B. Morton, Alex J. McLellan, Geoffrey Lee, Jonathan M. Kalman, Andrew D. McGavigan, Peter M. Kistler
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
S. Prabhu, N. Ahluwalia, S. M. Tyebally, A. S. C. Dennis, S. O. Malomo, A. T. Abiodun, A. Tyrlis, G. Dhillon, L. Segan, A. Graham, S. Honarbakhsh, V. Sawhney, S. Sporton, M. Lowe, M. Finlay, M. J. Earley, P. Lambiase, R. J. Schilling, R. J. Hunter
Summary: Cryoablation has shown to be an effective treatment for atrial fibrillation in patients with heart failure, leading to significant improvements in left ventricular systolic function and functional status post procedure.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Hariharan Sugumar, David Chieng, Sandeep Prabhu, Aleksandr Voskoboinik, Robert D. Anderson, Ahmed Al-Kaisey, Geoffrey Lee, Alex J. McLellan, Joseph B. Morton, Andrew J. Taylor, Liang-Han Ling, Jonathan M. Kalman, Peter M. Kistler
Summary: In this study, it was found that junctional rhythm (JR) is necessary for successful catheter ablation of AVNRT. The cycle length of JR during radiofrequency (RF) was not predictive of success. Unintended junctional beat-atrial block during faster JR was associated with slow pathway block, but it should not be intentionally targeted as it is a precursor to fast pathway block.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Sandeep Prabhu, Louise Segan
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
David Chieng, Louise Segan, Hariharan Sugumar, Ahmed Al-Kaisey, Joshua Hawson, Benjamin M. Moore, Michael C. Y. Nam, Aleksandr Voskoboinik, Sandeep Prabhu, Liang-Han Ling, Jer Fuu Ng, Gregor Brown, Geoffrey Lee, Joseph Morton, Henry Debinski, Jonathan M. Kalman, Peter M. Kistler
Summary: This study compared the effects of higher power short duration (HPSD) and lower power longer duration (LPLD) radiofrequency ablation on the risk of oesophageal thermal injury (ETI) in atrial fibrillation (AF) patients. It found that both methods had similar rates of ETI, but HPSD ablation reduced the ablation time and AF recurrence rate.
Article
Cardiac & Cardiovascular Systems
David Chieng, Rodrigo Canovas, Louise Segan, Hariharan Sugumar, Aleksandr Voskoboinik, Sandeep Prabhu, Liang-Han Ling, Geoffrey Lee, Joseph B. Morton, David M. Kaye, Jonathan M. Kalman, Peter M. Kistler
Summary: This study aims to evaluate the associations between different types of coffee and incident outcomes. Findings show that decaffeinated, ground, and instant coffee, especially at 2-3 cups/day, are associated with significant reductions in cardiovascular disease and mortality. Ground and instant coffee are also associated with reduced arrhythmia.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jeremy William, Xiaoman Xiao, Anita Shirwaiker, Hitesh Patel, Sandeep Prabhu, Liang-Han Ling, Hariharan Sugamar, Justin Mariani, Peter Kistler, Aleksandr Voskoboinik
Summary: This study reviewed the diagnostic work-up of cardiac arrest patients with ventricular tachyarrhythmias and normal hearts. The results showed that the work-up was often incomplete, especially in younger adults. The utilization of second-line cardiac investigations, such as cardiac magnetic resonance imaging (CMR), was low, and there is a need for further study to establish a systematic diagnostic protocol.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Review
Nutrition & Dietetics
Chong-Su Kim
Summary: The gut microbiota plays a crucial role in brain function through the gut-brain axis. This review highlights the effects of gut microbiota-derived dietary metabolites on cell-to-cell interactions in the central nervous system, particularly microglia, astrocytes, and neuronal cells, affecting cognitive function, mood, and behavior. The review also discusses the potential of diet-induced microbial metabolite-based therapies as novel approaches to mental health treatment.
ADVANCES IN NUTRITION
(2024)