Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-04-27
DOI
10.1038/srep25095
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery
- (2015) Cory M. Johannessen et al. TRENDS IN GENETICS
- A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking
- (2014) Prisca Liberali et al. CELL
- Synthesis, characterization and Akt phosphorylation inhibitory activity of cyclopentanecarboxylate-substituted alkylphosphocholines
- (2013) Md. Maqusood Alam et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation
- (2013) Tamas Balla PHYSIOLOGICAL REVIEWS
- Endocytosis and Cancer
- (2013) I. Mellman et al. Cold Spring Harbor Perspectives in Biology
- Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis
- (2012) H. Song et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Where EGF Receptors Transmit Their Signals
- (2012) N. L. Lill et al. Science Signaling
- The intracellular trafficking pathway of transferrin
- (2011) Kristine M. Mayle et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Nocodazole is a High-Affinity Ligand for the Cancer-Related Kinases ABL, c-KIT, BRAF, and MEK
- (2011) Hwangseo Park et al. ChemMedChem
- Drug discovery in the age of systems biology: the rise of computational approaches for data integration
- (2011) Murat Iskar et al. CURRENT OPINION IN BIOTECHNOLOGY
- Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity
- (2011) Theonie Anastassiadis et al. NATURE BIOTECHNOLOGY
- Fission of Tubular Endosomes Triggers Endosomal Acidification and Movement
- (2011) Kumi Mesaki et al. PLoS One
- Receptor Sorting within Endosomal Trafficking Pathway Is Facilitated by Dynamic Actin Filaments
- (2011) Emiko Ohashi et al. PLoS One
- Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
- (2011) L. V. Sequist et al. Science Translational Medicine
- The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
- (2011) Michelle C. Mendoza et al. TRENDS IN BIOCHEMICAL SCIENCES
- Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells
- (2010) Wei-Lun Huang et al. Molecular Cancer
- Targeting Epidermal Growth Factor Receptor-Associated Signaling Pathways in Non-Small Cell Lung Cancer Cells: Implication in Radiation Response
- (2010) E. J. Choi et al. MOLECULAR CANCER RESEARCH
- Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth
- (2010) Josette Carnahan et al. MOLECULAR CANCER THERAPEUTICS
- Differential effects of the phosphatidylinositol 4-kinases, PI4KIIα and PI4KIIIβ, on Akt activation and apoptosis
- (2010) K M E Chu et al. Cell Death & Disease
- Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation: Table 1
- (2009) Philip Cohen BIOCHEMICAL JOURNAL
- Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds
- (2009) Yan Feng et al. NATURE REVIEWS DRUG DISCOVERY
- S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton
- (2009) Chao Zhang et al. PLoS One
- Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition
- (2009) Véronique Calleja et al. PLOS BIOLOGY
- Novel MEK1 Mutation Identified by Mutational Analysis of Epidermal Growth Factor Receptor Signaling Pathway Genes in Lung Adenocarcinoma
- (2008) J. L. Marks et al. CANCER RESEARCH
- Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation
- (2008) Sara Sigismund et al. DEVELOPMENTAL CELL
- Endocytosis and intracellular trafficking of ErbBs
- (2008) Alexander Sorkin et al. EXPERIMENTAL CELL RESEARCH
- Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK
- (2008) Klaus Dittmann et al. Molecular Cancer
- EGFR Antagonists in Cancer Treatment
- (2008) Fortunato Ciardiello et al. NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now