Functional characterization of ent-copalyl diphosphate synthase, kaurene synthase and kaurene oxidase in the Salvia miltiorrhiza gibberellin biosynthetic pathway

Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer

(2015) Radha Munagala et al.   CANCER LETTERS

Tanshinone I selectively suppresses pro-inflammatory genes expression in activated microglia and prevents nigrostriatal dopaminergic neurodegeneration in a mouse model of Parkinson׳s disease

(2015) Shaoxia Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Identification of geranylgeranyl diphosphate synthase genes from Tripterygium wilfordii

(2015) Meng Zhang et al.   PLANT CELL REPORTS

Producing aglycons of ginsenosides in bakers' yeast

(2014) Zhubo Dai et al.   Scientific Reports

RNA interference-mediated repression of SmCPS (copalyldiphosphate synthase) expression in hairy roots of Salvia miltiorrhiza causes a decrease of tanshinones and sheds light on the functional role of SmCPS

(2013) Qiqing Cheng et al.   BIOTECHNOLOGY LETTERS

Cryptotanshinone and dihydrotanshinone I exhibit strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation

(2013) Ming Cong et al.   FITOTERAPIA

PF2401-SF, standardized fraction of Salvia miltiorrhiza shows anti-inflammatory activity in macrophages and acute arthritis in vivo

(2013) Wen-Yi Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

(2013) Zhubo Dai et al.   METABOLIC ENGINEERING

CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts

(2013) J. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza

(2012) Yimian Ma et al.   JOURNAL OF EXPERIMENTAL BOTANY

Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

(2012) Yongjin J. Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate

(2012) Nils Günnewich et al.   PHYTOCHEMISTRY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Peroxyl radical scavenging capacity of extracts and isolated components from selected medicinal plants

(2010) Sun Ju Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis

(2010) Dana Morrone et al.   BIOCHEMICAL JOURNAL

Metabolic Engineering of Saccharomyces cerevisiae for Astaxanthin Production and Oxidative Stress Tolerance

(2009) K. Ukibe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights

(2009) Wei Gao et al.   ORGANIC LETTERS