Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages

Is the Consensus Value of ANU Sucrose (IAEA C-6) Too High?

(2016) Xiaomei Xu et al.   RADIOCARBON

Automated Combustion Accelerator Mass Spectrometry for the Analysis of Biomedical Samples in the Low Attomole Range

(2014) Esther van Duijn et al.   ANALYTICAL CHEMISTRY

Prophylactic Treatment with Alkaline Phosphatase in Cardiac Surgery Induces Endogenous Alkaline Phosphatase Release

(2012) Suzanne Kats et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

The 1MV multi-element AMS system for biomedical applications at the Netherlands Organization for Applied Scientific Research (TNO)

(2012) Matthias Klein et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

European Bioanalysis Forum recommendation: scientific validation of quantification by accelerator mass spectrometry

(2012) David Higton et al.   Bioanalysis

Iodine-129 microdosing for protein and peptide drug development: erythropoietin as a case study

(2012) Robert-Jan AN Lamers et al.   Bioanalysis

Microdosing studies using accelerated mass spectrometry as exploratory investigational new drug trials

(2011) Soo Kyung Bae et al.   ARCHIVES OF PHARMACAL RESEARCH

Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers

(2011) Graham Lappin et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Translational research: 4 ways to fix the clinical trial

(2011) Heidi Ledford   NATURE

Impact of microdosing clinical study — Why necessary and how useful?

(2010) Yuichi Sugiyama et al.   ADVANCED DRUG DELIVERY REVIEWS

Accelerator mass spectrometry offers new opportunities for microdosing of peptide and protein pharmaceuticals

(2010) Mehran Salehpour et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Human microdosing for the prediction of patient response

(2010) Paul T Henderson et al.   Bioanalysis

Analytical validation of accelerator mass spectrometry for pharmaceutical development

(2010) Bradly D Keck et al.   Bioanalysis

Safety Assessment and Dose Selection for First-in-Human Clinical Trials With Immunomodulatory Monoclonal Antibodies

(2009) PY Muller et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Subattomole Sensitivity in Biological Accelerator Mass Spectrometry

(2008) Mehran Salehpour et al.   ANALYTICAL CHEMISTRY