The γ-Protocadherin-C3 isoform inhibits canonical Wnt signalling by binding to and stabilizing Axin1 at the membrane

Homophilic Protocadherin Cell-Cell Interactions Promote Dendrite Complexity

(2016) Michael J. Molumby et al.   Cell Reports

Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions

(2015) Rotem Rubinstein et al.   CELL

Protein Kinase C Phosphorylation of a γ-Protocadherin C-terminal Lipid Binding Domain Regulates Focal Adhesion Kinase Inhibition and Dendrite Arborization

(2015) Austin B. Keeler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice

(2015) Reiko Meguro et al.   JOURNAL OF NEUROCHEMISTRY

Emerging roles of Axin in cerebral cortical development

(2015) Tao Ye et al.   Frontiers in Cellular Neuroscience

Protocadherins branch out: Multiple roles in dendrite development

(2015) Austin B Keeler et al.   Cell Adhesion & Migration

Protocadherin-dependent dendritic self-avoidance regulates neural connectivity and circuit function

(2015) Dimitar Kostadinov et al.   eLife

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling

(2015) Yu Chen et al.   PLoS One

Single-Cell Identity Generated by Combinatorial Homophilic Interactions between α, β, and γ Protocadherins

(2014) Chan Aye Thu et al.   CELL

Wnt signalling in neuronal differentiation and development

(2014) Nibaldo C. Inestrosa et al.   CELL AND TISSUE RESEARCH

Developmental Epigenetic Modification Regulates Stochastic Expression of Clustered Protocadherin Genes, Generating Single Neuron Diversity

(2014) Shunsuke Toyoda et al.   NEURON

Sorting out a promiscuous superfamily: towards cadherin connectomics

(2014) Marcos Sotomayor et al.   TRENDS IN CELL BIOLOGY

New insights into the regulation of Axin function in canonical Wnt signaling pathway

(2014) Xiaomin Song et al.   Protein & Cell

Wnt Stabilization of  -Catenin Reveals Principles for Morphogen Receptor-Scaffold Assemblies

(2013) S.-E. Kim et al.   SCIENCE

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

(2012) Paul L. Severson et al.   Epigenetics

Wnt-11 and Fz7 reduce cell adhesion in convergent extension by sequestration of PAPC and C-cadherin

(2012) Bianca Kraft et al.   JOURNAL OF CELL BIOLOGY

Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

(2012) Julie L. Lefebvre et al.   NATURE

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

γ-Protocadherins Control Cortical Dendrite Arborization by Regulating the Activity of a FAK/PKC/MARCKS Signaling Pathway

(2012) Andrew M. Garrett et al.   NEURON

Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways

(2012) A R Dallosso et al.   ONCOGENE

Restoration of Contralateral Representation in the Mouse Somatosensory Cortex after Crossing Nerve Transfer

(2012) Haruyoshi Yamashita et al.   PLoS One

Differential Role of Axin RGS Domain Function in Wnt Signaling during Anteroposterior Patterning and Maternal Axis Formation

(2012) Patricia N. Schneider et al.   PLoS One

Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase

(2012) Lun Suo et al.   Journal of Molecular Cell Biology

Wnt Signaling and Forebrain Development

(2012) S. J. Harrison-Uy et al.   Cold Spring Harbor Perspectives in Biology

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

Molecular codes for neuronal individuality and cell assembly in the brain

(2012) Takeshi Yagi   Frontiers in Molecular Neuroscience

Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems

(2012) Keizo Hirano et al.   Frontiers in Molecular Neuroscience

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse

(2011) Anna Ferrer-Vaquer et al.   BMC DEVELOPMENTAL BIOLOGY

PAPC and the Wnt5a/Ror2 pathway control the invagination of the otic placode in Xenopus

(2011) Barbara Jung et al.   BMC DEVELOPMENTAL BIOLOGY

Xenopus paraxial protocadherin inhibits Wnt/β-catenin signalling via casein kinase 2β

(2011) Anja Kietzmann et al.   EMBO REPORTS

Identification of the Cluster Control Region for the Protocadherin-β Genes Located beyond the Protocadherin-γ Cluster

(2011) Shinnichi Yokota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

(2011) Jason D. Berndt et al.   JOURNAL OF CELL BIOLOGY

Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation

(2011) Mark A. Lobas et al.   JOURNAL OF NEUROCHEMISTRY

Cdk5-Mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development

(2011) W.-Q. Fang et al.   JOURNAL OF NEUROSCIENCE

A pyrosequencing assay for the quantitative methylation analysis of the PCDHB gene cluster, the major factor in neuroblastoma methylator phenotype

(2011) Barbara Banelli et al.   LABORATORY INVESTIGATION

Regulatory elements required for the activation and repression of the protocadherin-  gene cluster

(2011) P. Kehayova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the γ-Protocadherins

(2011) Tuhina Prasad et al.   Frontiers in Molecular Neuroscience

Combinatorial homophilic interaction between  -protocadherin multimers greatly expands the molecular diversity of cell adhesion

(2010) D. Schreiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice

(2009) Hong Su et al.   DEVELOPMENTAL BIOLOGY

Membrane Bound Axin Is Sufficient for Wingless Signaling in Drosophila Embryos

(2009) N. S. Tolwinski   GENETICS

Threonine 393 of β-catenin regulates interaction with Axin

(2009) Hao Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Control of CNS Synapse Development by  -Protocadherin-Mediated Astrocyte-Neuron Contact

(2009) A. M. Garrett et al.   JOURNAL OF NEUROSCIENCE

Protocadherin-  Family Is Required for Serotonergic Projections to Appropriately Innervate Target Brain Areas

(2009) S. Katori et al.   JOURNAL OF NEUROSCIENCE

Proteomics Analysis Reveals Overlapping Functions of Clustered Protocadherins

(2009) Meng-Hsuan Han et al.   MOLECULAR & CELLULAR PROTEOMICS

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Frequent Long-Range Epigenetic Silencing of Protocadherin Gene Clusters on Chromosome 5q31 in Wilms' Tumor

(2009) Anthony R. Dallosso et al.   PLoS Genetics

A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-  gene cluster

(2008) T. Prasad et al.   DEVELOPMENT

 -Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina

(2008) J. L. Lefebvre et al.   DEVELOPMENT

The protocadherin-α family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse

(2008) Sonoko Hasegawa et al.   MOLECULAR AND CELLULAR NEUROSCIENCE