Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform

Mutations in DDX58, which Encodes RIG-I, Cause Atypical Singleton-Merten Syndrome

(2015) Mi-Ae Jang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection

(2015) Stefanie Buerger et al.   JOURNAL OF IMMUNOLOGY

TRIM25 has a dual function in the p53/Mdm2 circuit

(2015) P Zhang et al.   ONCOGENE

Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying  -Catenin Degradation

(2014) R. Yuan et al.   CANCER RESEARCH

The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice

(2014) V. Spinnenhirn et al.   JOURNAL OF CELL SCIENCE

Active Caspase-1-Mediated Secretion of Retinoic Acid Inducible Gene-I

(2014) M.-J. Kim et al.   JOURNAL OF IMMUNOLOGY

Altered RIG-I/DDX58-mediated innate immunity in dermatomyositis

(2014) Xavier Suárez-Calvet et al.   JOURNAL OF PATHOLOGY

Hijacking of RIG-I Signaling Proteins into Virus-Induced Cytoplasmic Structures Correlates with the Inhibition of Type I Interferon Responses

(2014) F. W. Santiago et al.   JOURNAL OF VIROLOGY

NFκB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53

(2014) Yongwook Choi et al.   Molecular Oncology

HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1

(2014) Yanyan Peng et al.   PLoS Pathogens

Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses

(2013) C. S. Ng et al.   JOURNAL OF VIROLOGY

As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3β pathway

(2013) L Liu et al.   ONCOGENE

Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS

(2012) Samuel Buchsbaum et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation

(2012) A. Aichem et al.   JOURNAL OF CELL SCIENCE

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

(2011) Irving C. Allen et al.   IMMUNITY

FAT10 Protein Binds to Polyglutamine Proteins and Modulates Their Solubility

(2011) Yu Nagashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FAT10 mediates the effect of TNF-  in inducing chromosomal instability

(2011) J. Ren et al.   JOURNAL OF CELL SCIENCE

FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination

(2011) Samuel Buchsbaum et al.   MOLECULAR BIOLOGY OF THE CELL

5′-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity

(2011) Sun-Young Hwang et al.   NUCLEIC ACIDS RESEARCH

NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways

(2010) Jun Cui et al.   CELL

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I

(2010) M. Solis et al.   JOURNAL OF VIROLOGY

SUMOylation of RIG-I positively regulates the type I interferon signaling

(2010) Zhiqiang Mi et al.   Protein & Cell

Retinoic Acid-induced Gene-1 (RIG-I) Associates with the Actin Cytoskeleton via Caspase Activation and Recruitment Domain-dependent Interactions

(2009) Amitava Mukherjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FAT10: a Novel Mediator of Vpr-Induced Apoptosis in Human Immunodeficiency Virus-Associated Nephropathy

(2009) A. Snyder et al.   JOURNAL OF VIROLOGY

Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system

(2008) T. C. Tuoc et al.   GENES & DEVELOPMENT

The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition

(2008) B. Kalveram et al.   JOURNAL OF CELL SCIENCE

Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon

(2008) S Lukasiak et al.   ONCOGENE

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

(2008) M. U. Gack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA