Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I

Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure

(2016) Ewart W. Kuijk et al.   Scientific Reports

Cell therapy for liver disease: From liver transplantation to cell factory

(2015) Stuart J. Forbes et al.   JOURNAL OF HEPATOLOGY

Off-target mutations are rare in Cas9-modified mice

(2015) Vivek Iyer et al.   NATURE METHODS

Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes

(2014) Pengyu Huang et al.   Cell Stem Cell

Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes

(2014) Branden D. Tarlow et al.   Cell Stem Cell

RAG1/2 Knockout Pigs with Severe Combined Immunodeficiency

(2014) J. Huang et al.   JOURNAL OF IMMUNOLOGY

Mouse liver repopulation with hepatocytes generated from human fibroblasts

(2014) Saiyong Zhu et al.   NATURE

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

(2014) Yanjiao Shao et al.   Nature Protocols

Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease

(2014) Raymond D. Hickey et al.   Stem Cell Research

Adipose-Derived Stem Cells Can Abrogate Chemical-Induced Liver Fibrosis and Facilitate Recovery of Liver Function

(2013) Horng-Jyh Harn et al.   CELL TRANSPLANTATION

Mice With Human Livers

(2013) Markus Grompe et al.   GASTROENTEROLOGY

Repopulation of the fibrotic/cirrhotic rat liver by transplanted hepatic stem/progenitor cells and mature hepatocytes

(2013) Mladen I. Yovchev et al.   HEPATOLOGY

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

(2013) Meritxell Huch et al.   NATURE

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems

(2013) Wei Li et al.   NATURE BIOTECHNOLOGY

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

(2013) Dali Li et al.   NATURE BIOTECHNOLOGY

Cell fate conversion: Direct induction of hepatocyte-like cells from fibroblasts

(2012) Shuyi Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Retake the Center Stage – New Development of Rat Genetics

(2012) Sushuang Zheng et al.   Journal of Genetics and Genomics

Generation and Characterization of Severe Combined Immunodeficiency Rats

(2012) Tomoji Mashimo et al.   Cell Reports

Efficient production of Fah -null heterozygote pigs by chimeric adeno-associated virus-mediated gene knockout and somatic cell nuclear transfer

(2011) Raymond D. Hickey et al.   HEPATOLOGY

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

Liver Xeno-Repopulation with Human Hepatocytes in Fah−/−Rag2−/− Mice after Pharmacological Immunosuppression

(2010) Zhiying He et al.   AMERICAN JOURNAL OF PATHOLOGY

Transplantation of Human Wharton's Jelly-Derived Stem Cells Alleviates Chemically Induced Liver Fibrosis in Rats

(2010) Shinn-Zong Lin et al.   CELL TRANSPLANTATION

Transplantation of Human Amnion Epithelial Cells Reduces Hepatic Fibrosis in Immunocompetent CCl4-Treated Mice

(2010) Ursula Manuelpillai et al.   CELL TRANSPLANTATION

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

(2010) Karl-Dimiter Bissig et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

Loss of p21 Permits Carcinogenesis from Chronically Damaged Liver and Kidney Epithelial Cells despite Unchecked Apoptosis

(2008) Holger Willenbring et al.   CANCER CELL

NTBC treatment in tyrosinaemia type I: Long-term outcome in French patients

(2008) A. Masurel-Paulet et al.   JOURNAL OF INHERITED METABOLIC DISEASE