Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model

A microfluidically perfused three dimensional human liver model

(2015) Knut Rennert et al.   BIOMATERIALS

Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

(2015) Irina N. Shalova et al.   IMMUNITY

Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow

(2015) Mandy B. Esch et al.   LAB ON A CHIP

Serum lipid profile, cytokine production, and clinical outcome in patients with severe sepsis

(2014) Alexandra Lekkou et al.   JOURNAL OF CRITICAL CARE

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

ICAM-1 signaling in endothelial cells

(2014) Charlotte Lawson et al.   Pharmacological Reports

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Soluble Adhesion Molecules Correlate with Surface Expression in anIn VitroModel of Endothelial Activation

(2013) Anders G. Kjaergaard et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The liver in sepsis

(2013) Michael Bauer et al.   Current Opinion in Critical Care

Inflammatory and endothelial activation biomarkers and risk of sepsis: A nested case-control study

(2013) Henry E. Wang et al.   JOURNAL OF CRITICAL CARE

A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture

(2013) Ilka Wagner et al.   LAB ON A CHIP

The Transcriptomic Response of Rat Hepatic Stellate Cells to Endotoxin: Implications for Hepatic Inflammation and Immune Regulation

(2013) Stephen A. K. Harvey et al.   PLoS One

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-cell type human liver microtissues for hepatotoxicity testing

(2012) S. Messner et al.   ARCHIVES OF TOXICOLOGY

Organotypic liver culture models: Meeting current challenges in toxicity testing

(2012) Edward L. LeCluyse et al.   CRITICAL REVIEWS IN TOXICOLOGY

In vivo imaging of hepatic excretory function in the rat by fluorescence microscopy

(2012) Peter Recknagel et al.   Journal of Biophotonics

Sepsis Chronically in MARS: Systemic Cytokine Responses Are Always Mixed Regardless of the Outcome, Magnitude, or Phase of Sepsis

(2012) Marcin F. Osuchowski et al.   JOURNAL OF IMMUNOLOGY

Unique Cell Type-Specific Junctional Complexes in Vascular Endothelium of Human and Rat Liver Sinusoids

(2012) Cyrill Géraud et al.   PLoS One

Hepatic Fibrosis in a Long-term Murine Model of Sepsis

(2012) Falk A. Gonnert et al.   SHOCK

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

(2012) Peter Recknagel et al.   PLOS MEDICINE

Characteristics of Clinical Sepsis Reflected in a Reliable and Reproducible Rodent Sepsis Model

(2011) Falk A. Gonnert et al.   JOURNAL OF SURGICAL RESEARCH

Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS

(2010) Veronika Makó et al.   CYTOMETRY PART A

PECAM-1: Conflicts of interest in inflammation

(2010) Jamie R. Privratsky et al.   LIFE SCIENCES

Immunotherapy for Sepsis — A New Approach against an Ancient Foe

(2010) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hepatic and pancreatic stellate cells in focus

(2009) Claus Kordes et al.   BIOLOGICAL CHEMISTRY

Catecholamines induce an inflammatory response in human hepatocytes

(2009) Caroline Aninat et al.   CRITICAL CARE MEDICINE

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Phenotype for activated tissue macrophages in histiocytic necrotizing lymphadenitis

(2009) Yuko Nomura et al.   PATHOLOGY INTERNATIONAL

Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function

(2008) Sarah N. Campion et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Evolving concepts in liver tissue modeling and implications forin vitrotoxicology

(2008) André Guillouzo et al.   Expert Opinion on Drug Metabolism & Toxicology

Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury

(2008) Michael P. Holt et al.   JOURNAL OF LEUKOCYTE BIOLOGY