Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice

Differences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection

(2015) Ying Qin et al.   CLINICAL INFECTIOUS DISEASES

Intercontinental Spread of Asian-Origin H5N8 to North America through Beringia by Migratory Birds

(2015) Dong-Hun Lee et al.   JOURNAL OF VIROLOGY

Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial

(2015) Masashi Mizokami et al.   LANCET INFECTIOUS DISEASES

Intrahost Dynamics of Antiviral Resistance in Influenza A Virus Reflect Complex Patterns of Segment Linkage, Reassortment, and Natural Selection

(2015) Matthew B. Rogers et al.   mBio

Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck

(2015) Hassan Zaraket et al.   Nature Communications

Continuing challenges in influenza

(2014) Robert G. Webster et al.   Annals of the New York Academy of Sciences

A novel highly pathogenic H5N8 avian influenza virus isolated from a wild duck in China

(2014) Shengtao Fan et al.   Influenza and Other Respiratory Viruses

Heterologous Prime-Boost Vaccination Using an AS03B-Adjuvanted Influenza A(H5N1) Vaccine in Infants and Children

(2014) Terry Nolan et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of Susceptibility Variants of Influenza Virus Grown in the Presence of T-705

(2014) Tohru Daikoku et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Antiviral combinations for severe influenza

(2014) Jake Dunning et al.   LANCET INFECTIOUS DISEASES

Dual therapy with lopinavir and ritonavir plus lamivudine versus triple therapy with lopinavir and ritonavir plus two nucleoside reverse transcriptase inhibitors in antiretroviral-therapy-naive adults with HIV-1 infection: 48 week results of the randomised, open label, non-inferiority GARDEL trial

(2014) Pedro Cahn et al.   LANCET INFECTIOUS DISEASES

MOSAIK: A Hash-Based Algorithm for Accurate Next-Generation Sequencing Short-Read Mapping

(2014) Wan-Ping Lee et al.   PLoS One

Similar Prevalence of Low-Abundance Drug-Resistant Variants in Treatment-Naive Patients with Genotype 1a and 1b Hepatitis C Virus Infections as Determined by Ultradeep Pyrosequencing

(2014) Severine Margeridon-Thermet et al.   PLoS One

Genesis of avian influenza H9N2 in Bangladesh

(2014) Karthik Shanmuganatham et al.   Emerging Microbes & Infections

Histopathological Evaluation of the Diversity of Cells Susceptible to H5N1 Virulent Avian Influenza Virus

(2013) Haru Ogiwara et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanism of Action of T-705 Ribosyl Triphosphate against Influenza Virus RNA Polymerase

(2013) Hidehiro Sangawa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

A comparative study of ultra-deep pyrosequencing and cloning to quantitatively analyze the viral quasispecies using hepatitis B virus infection as a model

(2013) Clara Ramírez et al.   ANTIVIRAL RESEARCH

In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus

(2013) E. Bart Tarbet et al.   ARCHIVES OF VIROLOGY

V-Phaser 2: variant inference for viral populations

(2013) Xiao Yang et al.   BMC GENOMICS

Synergistic combinations of favipiravir and oseltamivir against wild-type pandemic and oseltamivir-resistant influenza A virus infections in mice

(2013) Donald F Smee et al.   Future Virology

T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

(2013) T. Baranovich et al.   JOURNAL OF VIROLOGY

Characterization of H7N9 influenza A viruses isolated from humans

(2013) Tokiko Watanabe et al.   NATURE

The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

(2013) Zhinan Jin et al.   PLoS One

Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice

(2012) E. Bart Tarbet et al.   ANTIVIRAL RESEARCH

Qualimap: evaluating next-generation sequencing alignment data

(2012) Fernando García-Alcalde et al.   BIOINFORMATICS

Dynamics of Hepatitis B Virus Quasispecies in Association with Nucleos(t)ide Analogue Treatment Determined by Ultra-Deep Sequencing

(2012) Norihiro Nishijima et al.   PLoS One

Combination of peramivir and rimantadine demonstrate synergistic antiviral effects in sub-lethal influenza A (H3N2) virus mouse model

(2010) Shanta Bantia et al.   ANTIVIRAL RESEARCH

Side effects of long-term oral antiviral therapy for hepatitis B

(2010) Robert J. Fontana   HEPATOLOGY

Benefits and risks of combination therapy for hepatitis B

(2010) Norah A. Terrault   HEPATOLOGY

Competitive Fitness of Oseltamivir-Sensitive and -Resistant Highly Pathogenic H5N1 Influenza Viruses in a Ferret Model

(2010) E. A. Govorkova et al.   JOURNAL OF VIROLOGY

Combination Chemotherapy for Influenza

(2010) Elena A. Govorkova et al.   Viruses-Basel

Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

(2009) D. F. Smee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Viral Loads and Duration of Viral Shedding in Adult Patients Hospitalized with Influenza

(2009) Nelson Lee et al.   JOURNAL OF INFECTIOUS DISEASES

Single-Reaction Genomic Amplification Accelerates Sequencing and Vaccine Production for Classical and Swine Origin Human Influenza A Viruses

(2009) B. Zhou et al.   JOURNAL OF VIROLOGY

Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico

(2009) Rogelio Perez-Padilla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Severe Respiratory Disease Concurrent with the Circulation of H1N1 Influenza

(2009) Gerardo Chowell et al.   NEW ENGLAND JOURNAL OF MEDICINE

T-705 (favipiravir) activity against lethal H5N1 influenza A viruses

(2009) M. Kiso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune responses to influenza A H5N1: friend or foe?

(2009) Joseph Sriyal Malik Peiris et al.   TRENDS IN IMMUNOLOGY

Pathology, Molecular Biology, and Pathogenesis of Avian Influenza A (H5N1) Infection in Humans

(2008) Christine Korteweg et al.   AMERICAN JOURNAL OF PATHOLOGY

Oseltamivir-Ribavirin Combination Therapy for Highly Pathogenic H5N1 Influenza Virus Infection in Mice

(2008) N. A. Ilyushina et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Factors associated with case fatality of human H5N1 virus infections in Indonesia: a case series

(2008) I Nyoman Kandun et al.   LANCET

Update on Avian Influenza A (H5N1) Virus Infection in Humans

(2008)   NEW ENGLAND JOURNAL OF MEDICINE