Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy
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Title
Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy
Authors
Keywords
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Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-09-14
DOI
10.1038/srep33176
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Note: Only part of the references are listed.- Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer’s disease-related microvascular cerebral amyloid angiopathy
- (2016) Mario Merlini et al. ACTA NEUROPATHOLOGICA
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1
- (2016) Masaya Tachibana et al. EXPERIMENTAL NEUROLOGY
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- (2016) Teresa Rodríguez-Martín et al. NEUROBIOLOGY OF DISEASE
- Evidence for the recruitment of autophagic vesicles in human brain after stroke
- (2016) Tony Frugier et al. NEUROCHEMISTRY INTERNATIONAL
- Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation
- (2015) Paula Korhonen et al. BRAIN BEHAVIOR AND IMMUNITY
- ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice
- (2015) Angela W. Corona et al. Journal of Neuroimmune Pharmacology
- Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity
- (2015) A. Mounier et al. JOURNAL OF NEUROSCIENCE
- Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate -Synuclein Disrupted Gene Expression
- (2015) N. Volakakis et al. JOURNAL OF NEUROSCIENCE
- Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity
- (2015) Vedad Delic et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage
- (2015) Yohei Shibuya et al. NEUROBIOLOGY OF AGING
- Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke
- (2015) Michelangelo Certo et al. PHARMACOLOGICAL RESEARCH
- Neuroprotective Effect of Bexarotene in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
- (2015) Javier Riancho et al. Frontiers in Cellular Neuroscience
- Mitofusin 2-Deficiency Suppresses Cell Proliferation through Disturbance of Autophagy
- (2015) Yanhong Ding et al. PLoS One
- Bexarotene Reduces Blood-Brain Barrier Permeability in Cerebral Ischemia-Reperfusion Injured Rats
- (2015) Lu Xu et al. PLoS One
- Primary age-related tauopathy (PART): a common pathology associated with human aging
- (2014) John F. Crary et al. ACTA NEUROPATHOLOGICA
- Retinoid X Receptor Agonists Inhibit Hypertension-Induced Myocardial Hypertrophy by Modulating LKB1/AMPK/p70S6K Signaling Pathway
- (2014) Jiang Zhu et al. AMERICAN JOURNAL OF HYPERTENSION
- Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target
- (2014) Brandon B. Holmes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy: a double-edged sword for neuronal survival after cerebral ischemia
- (2014) Kangyong Liu et al. Neural Regeneration Research
- Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy
- (2014) Valerie Bomben et al. NEUROBIOLOGY OF AGING
- Ginsenoside Rd Attenuates Tau Protein Phosphorylation Via the PI3K/AKT/GSK-3β Pathway After Transient Forebrain Ischemia
- (2014) Xiao Zhang et al. NEUROCHEMICAL RESEARCH
- Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage
- (2014) Seung-Hoon Baek et al. STROKE
- Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson’s Disease
- (2013) Krista McFarland et al. ACS Chemical Neuroscience
- Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series
- (2013) Gabor G. Kovacs et al. ACTA NEUROPATHOLOGICA
- Cerebrospinal fluid biomarkers in Alzheimer’s disease, vascular dementia and ischemic stroke patients: a critical analysis
- (2013) Lisa Kaerst et al. JOURNAL OF NEUROLOGY
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- Comment on "ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models"
- (2013) N. F. Fitz et al. SCIENCE
- Distal Occlusion of the Middle Cerebral Artery in Mice: Are We Ready to Assess Long-Term Functional Outcome?
- (2013) Anna Rosell et al. Translational Stroke Research
- A Double-Edged Sword with Therapeutic Potential: An Updated Role of Autophagy in Ischemic Cerebral Injury
- (2012) Kai Wei et al. CNS Neuroscience & Therapeutics
- Gait analysis as a method for assessing neurological outcome in a mouse model of stroke
- (2012) Susann Hetze et al. JOURNAL OF NEUROSCIENCE METHODS
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β
- (2010) Maya A. Koike et al. AMERICAN JOURNAL OF PATHOLOGY
- Age-Related Differences in Characteristics, Performance Measures, Treatment Trends, and Outcomes in Patients With Ischemic Stroke
- (2010) Gregg C. Fonarow et al. CIRCULATION
- Aggregation of Detergent-insoluble Tau Is Involved in Neuronal Loss but Not in Synaptic Loss
- (2010) Tetsuya Kimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ischemic stroke in the elderly: an overview of evidence
- (2010) Ruo-Li Chen et al. Nature Reviews Neurology
- Review: Autophagy and neurodegeneration: survival at a cost?
- (2010) S. J. Cherra III et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Regulation of Mammalian Autophagy in Physiology and Pathophysiology
- (2010) Brinda Ravikumar et al. PHYSIOLOGICAL REVIEWS
- Motor control and aging: Links to age-related brain structural, functional, and biochemical effects
- (2009) Rachael D. Seidler et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Mitochondrial Targets for Stroke
- (2009) Peter S. Vosler et al. STROKE
- Reduced early hypoxic/ischemic brain damage is associated with increased GLT-1 levels in mice expressing mutant (P301L) human tau
- (2008) Guanghong Liao et al. BRAIN RESEARCH
- Age, experience and genetic background influence treadmill walking in mice
- (2008) Christine M. Wooley et al. PHYSIOLOGY & BEHAVIOR
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