Differential protein structural disturbances and suppression of assembly partners produced by nonsense GABRG2 epilepsy mutations: implications for disease phenotypic heterogeneity

Minimalistic Predictor of Protein Binding Energy: Contribution of Solvation Factor to Protein Binding

(2015) Jeong-Mo Choi et al.   BIOPHYSICAL JOURNAL

The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration

(2015) Jing-Qiong Kang et al.   NATURE NEUROSCIENCE

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

A Novel GABRG2 mutation, p.R136*, in a family with GEFS+ and extended phenotypes

(2014) Ann J. Johnston et al.   NEUROBIOLOGY OF DISEASE

Trafficking-deficient mutant GABRG2 subunit amount may modify epilepsy phenotype

(2013) Jing-Qiong Kang et al.   ANNALS OF NEUROLOGY

Template-based structure modeling of protein–protein interactions

(2013) Andras Szilagyi et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Computational Systems Biology Study for Understanding Salt Tolerance Mechanism in Rice

(2013) Juexin Wang et al.   PLoS One

The PyRosetta Toolkit: A Graphical User Interface for the Rosetta Software Suite

(2013) Jared Adolf-Bryfogle et al.   PLoS One

Protein-protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area

(2013) Jieming Chen et al.   PROTEIN SCIENCE

Predicting protein-protein interactions on a proteome scale by matching evolutionary and structural similarities at interfaces using PRISM

(2011) Nurcan Tuncbag et al.   Nature Protocols

Polymorphic Structures of Alzheimer's β-Amyloid Globulomers

(2011) Xiang Yu et al.   PLoS One

Anchored Design of Protein-Protein Interfaces

(2011) Steven M. Lewis et al.   PLoS One

Structure-guided forcefield optimization

(2011) Yifan Song et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Slow Degradation and Aggregation In Vitro of Mutant GABAA Receptor  2(Q351X) Subunits Associated with Epilepsy

(2010) J.-Q. Kang et al.   JOURNAL OF NEUROSCIENCE

Two Molecular Pathways (NMD and ERAD) Contribute to a Genetic Epilepsy Associated with the GABAA Receptor GABRA1 PTC Mutation, 975delC, S326fs328X

(2009) J.-Q. Kang et al.   JOURNAL OF NEUROSCIENCE

The GABRG2 Mutation, Q351X, Associated with Generalized Epilepsy with Febrile Seizures Plus, Has Both Loss of Function and Dominant-Negative Suppression

(2009) J.-Q. Kang et al.   JOURNAL OF NEUROSCIENCE

MUFOLD: A new solution for protein 3D structure prediction

(2009) Jingfen Zhang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Making sense of nonsense GABAA receptor mutations associated with genetic epilepsies

(2009) Jing-Qiong Kang et al.   TRENDS IN MOLECULAR MEDICINE

A Conserved Cys-loop Receptor Aspartate Residue in the M3-M4 Cytoplasmic Loop Is Required for GABAAReceptor Assembly

(2008) Wen-yi Lo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCN1A, SCN1B, and GABRG2 gene mutation analysis in Chinese families with generalized epilepsy with febrile seizures plus

(2008) Huihui Sun et al.   JOURNAL OF HUMAN GENETICS