NAD+ regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4+ CD25+ Foxp3+ T cells independent

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

(2015) Nicola Gagliani et al.   NATURE

Tuning IL-2 signaling by ADP-ribosylation of CD25

(2015) Sophie Teege et al.   Scientific Reports

NAD+ protects against EAE by regulating CD4+ T-cell differentiation

(2014) Stefan G. Tullius et al.   Nature Communications

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

(2013) Nicola Gagliani et al.   NATURE MEDICINE

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease

(2012) Arian Laurence et al.   IMMUNITY

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

(2011) Ilona Kryczek et al.   JOURNAL OF IMMUNOLOGY

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

(2010) T. Woehrle et al.   BLOOD

Receptor localization, native tissue binding and ex vivo occupancy for centrally penetrant P2X7 antagonists in the rat

(2010) SL Able et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP

(2010) A Casati et al.   CELL DEATH AND DIFFERENTIATION

Inflammation and the balance of Treg and Th17 cells in transplant rejection and tolerance

(2010) Dusan Hanidziar et al.   Current Opinion in Organ Transplantation

The impact of Th17 cells on transplant rejection and the induction of tolerance

(2010) Sebastiaan Heidt et al.   Current Opinion in Organ Transplantation

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors

(2010) Jinfang Zhu et al.   IMMUNOLOGICAL REVIEWS

Extracellular NAD+shapes the Foxp3+regulatory T cell compartment through the ART2–P2X7 pathway

(2010) Sandra Hubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation and Function of Proinflammatory TH17 Cells

(2009) Gustavo J. Martinez et al.   Annals of the New York Academy of Sciences

IL-17-producing human peripheral regulatory T cells retain suppressive function

(2009) G. Beriou et al.   BLOOD

Developmental plasticity of Th17 and Treg cells

(2009) Yun Kyung Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Regulatory T cells that become autoaggressive

(2009) Daniel Hawiger et al.   NATURE IMMUNOLOGY

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the TH17 lineage-specific transcription factor ROR t

(2009) M. Ayyoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the P2X7 ion channel by soluble and covalently bound ligands

(2009) Nicole Schwarz et al.   Purinergic Signalling

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors

(2008) Diana L. Donnelly-Roberts et al.   NEUROPHARMACOLOGY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology