Article
Biochemistry & Molecular Biology
Andrea Macrelli, Nicolo Simone Villa, Andrea Lucotti, David Dellasega, Paolo Maria Ossi, Matteo Tommasini
Summary: This paper presents a cost-effective method for producing SERS sensors by depositing Lee-Meisel Ag colloids on filter paper. The sensors were characterized by optical microscopy, SEM, and UV-Vis spectroscopy. It was demonstrated that these sensors can be used for quantitative measurement of the anti-epileptic drug Perampanel by SERS.
Article
Chemistry, Analytical
Menbere Leul Mekonnen, Yitayal Admassu Workie, Wei-Nien Su, Bing Joe Hwang
Summary: This review discusses the fabrication of low-cost, flexible SERS substrates using paper, highlighting its advantages and methods. It evaluates the pros and cons of different fabrication methods, and explores ways to improve substrate performance and obtain additional analytical functionalities. Finally, it also suggests opportunities and challenges in realizing a low-cost commercial plasmonic paper substrate.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Engineering, Electrical & Electronic
Tania K. Naqvi, Abhilash Bajpai, Sarthak Dwivedi, Manish Bhaiyya, Sanket Goel, Prabhat K. Dwivedi
Summary: In this study, a low-cost, label-free flexible paper-based microfluidic SERS sensor was developed for thiram detection. Hydrophilic wells of different sizes were created on paper using wax-coated mould printing, and the hydrophilic nature of the wells was confirmed. Silver nanoparticles decorated graphene oxide nano-hybrid (Ag-rGO) was synthesized and drop-casted onto the wells for thiram detection, achieving fM sensitivity with a low limit of detection and high enhancement factor. The reproducibility and uniformity of the fabricated substrates were tested, showing good results. The Ag-rGO/wax paper (Ag-rGO/WP) SERS sensor has the potential to be used as a portable sensing platform for food safety applications.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Article
Engineering, Biomedical
J. M. Romo-Herrera, K. Juarez-Moreno, L. Guerrini, Y. Kang, N. Feliu, W. J. Parak, R. A. Alvarez-Puebla
Summary: Paper as a scaffold material meets key requirements for cell culture applications and can mimic cellular micro-environment. Integration of plasmonic nanomaterials allows the generation of multifunctional scaffolds for monitoring different cell cues. Paper-based plasmonic substrates in combination with SERS optical detection represent a powerful future platform for monitoring cell cues during cell culture processes.
MATERIALS TODAY BIO
(2021)
Article
Chemistry, Analytical
Natercia C. T. Martins, Sara Fateixa, Helena I. S. Nogueira, Tito Trindade
Summary: Fast detection of emerging contaminants in water resources is of great environmental interest. This study explores the application of chitosan-coated paper and silver nanoparticles for surface-enhanced Raman scattering (SERS) spectroscopy studies of two types of contaminants. The results show that the biocoated substrates have superior SERS performance compared to non-coated paper and successfully detect thiram and ciprofloxacin.
Article
Biochemistry & Molecular Biology
Viviana Mollica Nardo, Vincenzo Renda, Sebastiano Trusso, Rosina Celeste Ponterio
Summary: This paper details the fabrication, characterization, and testing of SERS-active substrates specifically designed for detecting pigments in artwork. The substrates were found to effectively amplify Raman scattering of various dyes and were stable in the pH range between 3 and 11. Additionally, vibrational DFT calculations provided a complete description of the observed SERS spectra.
Article
Chemistry, Analytical
Chih-Yi Liu, Rahul Ram, Rahim Bakash Kolaru, Shih-Hsin Chang, Sabyasachi Chakrabortty, Yi-Nan Lin, Cheng-Shane Chu, Sajal Biring
Summary: We have developed silver-nanostructures grown on anodic alumina nanomesh (AAN) films as new-type substrates for surface-enhanced Raman scattering (SERS). The deposition of silver on AAN films creates an array of nanoparticles or nano-islands, showing a non-monotonic evolution due to the competition between metal growth and dissolution. SERS study reveals the collective contribution of electron-plasma oscillation and surface area of silver nanostructures in Raman enhancements, suggesting the fabrication of SERS substrate with larger Ag surface area for high throughput applications in commercial sectors.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Applied
Nadzeya Khinevich, Hanna Bandarenka, Siarhei Zavatski, Kseniya Girel, Asta Tamuleviciene, Tomas Tamulevicius, Sigitas Tamulevicius
Summary: Surface-enhanced Raman scattering (SERS) spectroscopy is a promising method for highly sensitive detection of organic and bioorganic objects, but its practical use is hindered by limitations such as reproducibility, versatility, and commercially available substrates. By utilizing substrates composed of noble metals nanoparticles and porous silicon, these limitations can be overcome to achieve better performance and integration in silicon chips.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Spectroscopy
Marcos Mandado, Nicolas Ramos-Berdullas
Summary: Experimental and theoretical studies have shown that 2D hybrid structures formed by boron, nitrogen and carbon atoms possess highly tunable optical responses, motivating a significant amount of research in this area. By controlling the synthesis of these unique structures, it is possible to effectively confine and manipulate the optical responses, allowing for precise tuning and control.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Shengyuan Yao, Yan Lv, Qing Wang, Jinhui Yang, Hongmei Li, Ningning Gao, Furu Zhong, Jihong Fu, Jun Tang, Tao Wang, Dianzeng Jia
Summary: As a new 2D carbon allotrope, graphdiyne (GDY) with its unique electronic space arrangement structure has the characteristics of uniform pores and large specific surface area. A novel gold nanoparticles (Au NPs)/GDY/carbon cloth (CC) SERS substrate was fabricated using GDY nanowall as support. The substrate showed good sensitivity in detecting organic dyes.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Xinxi Zhang, Lulu Chen, Xuejiao Fang, Yunsheng Shang, Haixin Gu, Wenlin Jia, Guohai Yang, Yingqiu Gu, Lulu Qu
Summary: In this study, a disposable paper SERS substrate assembled with AuNP/HNT was prepared for the detection of chlorpyrifos residues in agricultural products. The AuNP/HNT paper substrate exhibited high SERS activity, good reproducibility, and long-term stability, and was successfully used for quantitative detection of chlorpyrifos. The results demonstrate the potential application value of AuNP/HNT paper-based SERS substrate in pesticide detection.
Article
Nanoscience & Nanotechnology
Natercia C. T. Martins, Sara Fateixa, Tiago Fernandes, Helena I. S. Nogueira, Tito Trindade
Summary: This study introduces a general method to fabricate hydrophobic paper-based SERS substrates and optimizes their performance by controlling factors such as the ratio of nanoparticles and the number of printing layers. The selected substrates showed good SERS performance for various analytes, with specific analysis conducted on the pesticide thiram. The one-step fabrication method is suggested to enhance the SERS performance of the paper substrates through nanoscale features of the hydrophobic coating.
ACS APPLIED NANO MATERIALS
(2021)
Article
Spectroscopy
Min Hou, Ning Li, Xiaoran Tian, Qian Yu, Juan-P. Hinestroza, Xianming Kong
Summary: Selectivity is important in SERS sensing due to the presence of particles and impurities in complex mixtures, which hinder laser-analyte interactions. This manuscript describes the development of a simple and instant method for preparing a filter paper SERS sensor, which demonstrates effective filtering and detection capabilities.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Physical
Jun-Yeong Yang, Sung-Gyu Park, Sunghoon Jung, Eun-Yeon Byeon, Do-geun Kim, Ho Sang Jung, Hyo Jung Kim, Seunghun Lee
Summary: This study utilized oxygen ion beam sputtering to fabricate gold nano-tips for surface-enhanced Raman spectroscopy (SERS), with finite-difference time-domain (FDTD) simulations showing that nano-tip structures with spacings of less than 10 nm increased the localized E field enhancement for stronger SERS signals. SERS substrates fabricated at a low energy density (5.8 J/cm²) showed higher nano-tip density and stronger Raman signal intensity compared to substrates fabricated at high energy density (17.3 J/cm²).
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Yulian Zeng, Fengyan Wang, Daxue Du, Shan Liu, Chenbo Wang, Zhaopeng Xu, Haiyan Wang
Summary: This study fabricated Ag/ZnO hybrid SERS substrates with high sensitivity and low detection limit by anchoring Ag nanoparticles on ZnO nanotower arrays without surface modifiers. The high SERS sensitivity is attributed to a combination of nanogaps and corners of Ag-NPs, as well as the retention of R6G molecules on ZnO nanotower nanosteps, allowing the molecules to access the hot-spot regions.
APPLIED SURFACE SCIENCE
(2021)