A concise approach to indoles via oxidative C-H amination of 2-alkenylanilines using dioxygen as the sole oxidant

A novel synthetic method to prepare indole derivatives from N-Ts-2-alkenylanilines has been achieved. This reaction is through an oxidative intramolecular C-H amination by using molecular oxygen as the sole oxidant. This protocol is operationally simple and environmental friendly, and provides a diverse range of substrate scope.