Article
Chemistry, Analytical
Yiyang Sun, Zhaorui Song, Xu Ni, Pierre Dramou, Hua He
Summary: This study constructed a new ratio fluorescent gel probe for the detection of dopamine. The probe has dual emission characteristics and achieves detection of dopamine by adjusting the energy conversion efficiency of the boronic acid-based ligand and Tb3+ ions, showing high sensitivity and selectivity. The probe has been successfully applied to detect dopamine in human serum samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Yongqiang Shi, Dandan Kong, Wenting Li, Yuzhen Wei, Xiao Wei, Fangfang Qu, Yahui Zhang, Pengcheng Nie, Xuping Feng, Yong He
Summary: In this study, a novel ratiometric fluorescent probe was developed for sensitive detection of jasmonic acid (JA) using NCQDs@Co-MOFs@MIPs. The probe exhibited dual-emissive performance due to the introduction of Co-MOFs, which prevented the self-aggregation of NCQDs and changed their surface charge. The imprinted recognition sites from MIPs improved the selectivity of the probe by specifically capturing JA molecules. The probe successfully quantified JA in the range of 1-800 ng/mL with a LOD of 0.35 ng/mL and showed potential for monitoring JA levels in crops.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biophysics
Yongqiang Shi, Lei Lin, Yuzhen Wei, Wenting Li, Pengcheng Nie, Yong He, Xuping Feng
Summary: A novel ratiometric aptasensor was developed using CQDs@ZIF8 and Apt-AuNPs for highly sensitive detection of ABA. The sensor showed increased sensitivity and selectivity in detecting ABA levels in rice seeds, offering a new strategy for ultra-sensitive measurement of biomolecules.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Multidisciplinary
Madison R. Herling, Ivan J. Dmochowski
Summary: To monitor the process of RNA delivery, we developed a pH probe based on 2'-OMe RNA that exhibits enhanced pH sensitivity by guanine proximal effect. The probe, in duplex with a DNA complement, showed a significant FAM fluorescence enhancement from pH 4.5 to pH 8.0, indicating endosomal entrapment and release when delivered to HeLa cells. Moreover, the probe, in complex with an antisense RNA complement, acted as an siRNA mimic and successfully achieved protein knockdown in HEK293T cells, demonstrating its potential for studying the localization and pH microenvironment of oligonucleotides.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Wenjing Qi, Lei Chen, Chengpei Du, Yi Wang
Summary: A dopamine-functionalized carbon nanodot ratiometric fluorescence probe for hypochlorite detection was developed. The probe exhibited high selectivity and sensitivity towards ClO-, and could accurately detect it in the presence of other ions and substances.
Article
Nanoscience & Nanotechnology
Li Zhang, Huaizhong Xing, Wei Liu, Zihan Wang, Yumin Hao, Huiping Wang, Wenjuan Dong, Yang Liu, Shaomin Shuang, Chuan Dong, Xiaojuan Gong
Summary: A ratiometric optical dual-mode probe was developed for the detection of doxorubicin (DOX) using 11-mercaptoundecanoic acid-functionalized carbon dots (MUA-CDs), showing good selectivity, high sensitivity, and excellent anti-interference performance. The probe was successfully utilized for DOX detection in serum, urine, and live cells, demonstrating satisfactory results.
ACS APPLIED NANO MATERIALS
(2021)
Article
Spectroscopy
Lizhen Liu, Meng Chen, Lin Yuan, Zhi Mi, Caiqing Li, Zhixiong Liu, Zezhong Chen, Ligang Wang, Feng Feng, Luqi Wu
Summary: A novel ratiometric fluorescent probe based on dual-emission carbon dots was developed for sensitive detection of salicylic acid. The probe showed a good linear relationship and low detection limits, and demonstrated satisfactory performance in actual samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Ling Zhu, Lujia Shi, Yiping Tan, Huaiyin Zhang, Jiacheng Yin, Chang Xu, Danlian Wu, Yunsu Ma
Summary: In this study, a sensitive ratiometric fluorescent nanosensor was developed by encapsulating carbon dots and cadmium telluride quantum dots into a metal-organic framework. This nanosensor exhibited high sensitivity and selectivity towards silver ions, and was successfully applied for the determination of Ag+ in lake water.
Article
Chemistry, Analytical
Shuo Wu, Xunxun Deng, Shiyu Zang, Xiaobo Liu, Yingyan Ma
Summary: Dopamine and PEI copolymerized nanodots with fluorescence emission and quenching properties were synthesized. The fluorescence and quenching properties of the nanodots can be controlled by adjusting the ratio of dopamine and PEI. These nanodots showed strong green fluorescence emission and high quenching efficiency, making them suitable for miRNA analysis. With their high quenching efficiency, stable fluorescence emission, easily assembled interface, and uniform morphology, these nanodots have great potential as a universal nanoplatform for ratiometric fluorescence nanoprobes.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xiaowei Mu, Xue Jiang, Yu Zhang, Xin Liu, Siqi Zhang, Wei Wang, Yibing Huang, Pinyi Ma, Daqian Song
Summary: The study introduces a novel fluorescent assay for detecting alkaline phosphatase using chitosan carbon dots and calcein, showing excellent applicability in HepG2 cells and human serum samples.
ANALYTICA CHIMICA ACTA
(2021)
Article
Nanoscience & Nanotechnology
Jiangbin Xu, Wei Yang, Yuanfa Liu
Summary: In this study, a dual-emission carbonized polymer dot (d-CPDs) fluorescent probe was developed to detect tertiary butylhydroquinone (TBHQ) in edible oils. The probe utilized blue fluorescent CPDs (b-CPDs) as the response signal and yellow fluorescent CPDs (y-CPDs) as the internal reference material. It was found that the blue fluorescence of b-CPDs was quenched by increasing Fe3+ ion concentration, but could be restored by TBHQ.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Dandan Zhao, Yijun Huang, Huixiang Ouyang, Bingfang Shi, Suping Li, Shengyu Chen, Shulin Zhao
Summary: A novel fluorescent probe incorporating Cu-doped carbon dots was developed for naked-eye discrimination of phenylenediamine isomers and highly sensitive ratiometric fluorescence detection of H2O2. The sensor showed outstanding peroxidase-like activity and stability, and was able to detect H2O2 with a detection limit of 5.0 nM, with potential applications in biologically related studies.
Article
Chemistry, Analytical
Xiao-Yue Tang, Yi-Ming Liu, Xiao-Lin Bai, Hao Yuan, Yi-Kao Hu, Xiao-Ping Yu, Xun Liao
Summary: The study developed a novel pretreatment-free method for dopamine detection using carbon dots, which showed good selectivity and accuracy in human serum sample tests. The method has the potential for dopamine detection and live-cell imaging due to its simplicity, cost-effectiveness, and sensitivity.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Yinhui Yi, Wei Zeng, Gangbing Zhu
Summary: A novel nanoprobe based on molybdenum disulfide quantum dots (MoS2 QDs) and cyclodextrin was developed for the fluorescent detection of parathion-methyl, with wide detection scope and excellent selectivity.
Article
Biophysics
Cunjin Wang, Huanxian Shi, Min Yang, Zhuoru Yao, Bin Zhang, Enzhou Liu, Xiaoyun Hu, Weiming Xue, Jun Fan
Summary: Sulfur and nitrogen co-doped carbon quantum dots (S,N-CQDs) were prepared and characterized in this work, showing potential application prospects in biocompatibility and fluorescence detection, especially for dopamine sensing with high sensitivity and low detection limit.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)