Cordycepin Prevents Bone Loss through Inhibiting Osteoclastogenesis by Scavenging ROS Generation

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Dual Effect of Cyanidin on RANKL-Induced Differentiation and Fusion of Osteoclasts

(2015) Ce Dou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fluid Flow-Induced Calcium Response in Osteoclasts: Signaling Pathways

(2014) Ping Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Late stages of the synchronized macrophage fusion in osteoclast formation depend on dynamin

(2014) Santosh K. Verma et al.   BIOCHEMICAL JOURNAL

MiR-7b directly targets DC-STAMP causing suppression of NFATc1 and c-Fos signaling during osteoclast fusion and differentiation

(2014) Ce Dou et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Nuclear Nrf2 Induction by Protein Transduction Attenuates Osteoclastogenesis

(2014) Hiroyuki Kanzaki et al.   FREE RADICAL BIOLOGY AND MEDICINE

The inhibition of RANK-ligand in the management of postmenopausal osteoporosis and related fractures: the role of denosumab

(2014) Anna Capozzi et al.   GYNECOLOGICAL ENDOCRINOLOGY

Cordycepin (3′-deoxyadenosine) Down-Regulates the Proinflammatory Cytokines in Inflammation-Induced Osteoporosis Model

(2014) Da-wei Zhang et al.   INFLAMMATION

Interferon regulatory factor 8 protects against cerebral ischaemic-reperfusion injury

(2014) Mei Xiang et al.   JOURNAL OF NEUROCHEMISTRY

Cordycepin Induces S Phase Arrest and Apoptosis in Human Gallbladder Cancer Cells

(2014) Xu-An Wang et al.   MOLECULES

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

(2014) Shoshana M. Bartell et al.   Nature Communications

Anti-inflammatory effects of cordycepin in lipopolysaccharide-stimulated RAW 264.7 macrophages through Toll-like receptor 4-mediated suppression of mitogen-activated protein kinases and NF-κB signaling pathways

(2014) Yung Hyun Choi et al.   Drug Design Development and Therapy

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

(2013) Xinbing Sui et al.   CANCER LETTERS

Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species-mediated mitochondrial death pathway

(2013) HYE HYEON LEE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The Keap1/Nrf2 Protein Axis Plays a Role in Osteoclast Differentiation by Regulating Intracellular Reactive Oxygen Species Signaling

(2013) Hiroyuki Kanzaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis

(2013) Claudia Goettsch et al.   JOURNAL OF CLINICAL INVESTIGATION

Antioxidants, like coenzyme Q10, selenite, and curcumin, inhibited osteoclast differentiation by suppressing reactive oxygen species generation

(2012) Ho-Jin Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cordycepin (3′-deoxyadenosine) attenuates age-related oxidative stress and ameliorates antioxidant capacity in rats

(2012) Thiyagarajan Ramesh et al.   EXPERIMENTAL GERONTOLOGY

Cordycepin suppresses TNF-α-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination

(2012) Zhenghua Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of polyadenylation reduces inflammatory gene induction

(2012) A. Kondrashov et al.   RNA

Cordycepin inhibits albumin-induced epithelial-mesenchymal transition of renal tubular epithelial cells by reducing reactive oxygen species production

(2011) Li Xiao et al.   FREE RADICAL RESEARCH

Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells

(2011) Jin-Woo Jeong et al.   TOXICOLOGY IN VITRO

Sense and Sensitivity: FOXO and ROS in Cancer Development and Treatment

(2010) Stephen S. Myatt et al.   ANTIOXIDANTS & REDOX SIGNALING

Calcium signaling in osteoclasts

(2010) Sung-Yong Hwang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Cordyceps fungi: natural products, pharmacological functions and developmental products

(2010) Xuanwei Zhou et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

JNK/FOXO-mediated Neuronal Expression of Fly Homologue of Peroxiredoxin II Reduces Oxidative Stress and Extends Life Span

(2009) Kyu-Sun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

(2009) Baohong Zhao et al.   NATURE MEDICINE

Cordycepin Suppresses Expression of Diabetes Regulating Genes by Inhibition of Lipopolysaccharide-induced Inflammation in Macrophages

(2009) Seulmee Shin et al.   Immune Network

High oxygen tension prolongs the survival of osteoclast precursors via macrophage colony-stimulating factor

(2008) Naomi Yamasaki et al.   BONE

Oxidative stress, free radicals and bone remodeling

(2008) Giuseppe Banfi et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Cordyceps – A traditional Chinese medicine and another fungal therapeutic biofactory?

(2008) R. Russell M. Paterson   PHYTOCHEMISTRY