Dual Effect of Cyanidin on RANKL-Induced Differentiation and Fusion of Osteoclasts

MiR-7b directly targets DC-STAMP causing suppression of NFATc1 and c-Fos signaling during osteoclast fusion and differentiation

(2014) Ce Dou et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Berry anthocyanins suppress the expression and secretion of proinflammatory mediators in macrophages by inhibiting nuclear translocation of NF-κB independent of NRF2-mediated mechanism

(2014) Sang Gil Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The flavonoid fisetin promotes osteoblasts differentiation through Runx2 transcriptional activity

(2014) Laurent Léotoing et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes

(2013) Yaoyao Jia et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The beneficial effect of Icaritin on osteoporotic bone is dependent on the treatment initiation timing in adult ovariectomized rats

(2013) Songlin Peng et al.   BONE

Tumor-Induced Osteoclast miRNA Changes as Regulators and Biomarkers of Osteolytic Bone Metastasis

(2013) Brian Ell et al.   CANCER CELL

Caffeine enhances osteoclast differentiation and maturation through p38 MAP kinase/Mitf and DC-STAMP/CtsK and TRAP pathway

(2013) Jiwon Choi et al.   CELLULAR SIGNALLING

IL-17A Stimulates the Progression of Giant Cell Tumors of Bone

(2013) M. Xu et al.   CLINICAL CANCER RESEARCH

Cyanidin-3-glucoside Extracted from Mulberry Fruit Can ReduceN-methyl-N-nitrosourea-Induced Retinal Degeneration in Rats

(2013) Seung Hee Lee et al.   CURRENT EYE RESEARCH

Antioxidative and Cardioprotective Properties of Anthocyanins from Defatted Dabai Extracts

(2013) Hock Eng Khoo et al.   Evidence-based Complementary and Alternative Medicine

Water Extract ofDryopteris crassirhizomaAttenuates Bone Loss by Suppressing Osteoclast Differentiation and Function

(2013) Hyunil Ha et al.   Evidence-based Complementary and Alternative Medicine

Resolvin E1 regulates osteoclast fusion via DC-STAMP and NFATc1

(2013) Min Zhu et al.   FASEB JOURNAL

Antioxidant and Antidiabetic Activities of Black Mung Bean (Vigna radiata L.)

(2013) Yang Yao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice

(2013) Hyun-Ju Kim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Uncoupling bone and cartilage destruction

(2013) Megan Cully   Nature Reviews Rheumatology

Açaí (Euterpe oleraceae Mart.) berry extract exerts neuroprotective effects against β-amyloid exposure in vitro

(2013) Daphne Yiu San Wong et al.   NEUROSCIENCE LETTERS

Assessment of the role of flavonoids for inducing osteoblast differentiation in isolated mouse bone marrow derived mesenchymal stem cells

(2013) Swati Srivastava et al.   PHYTOMEDICINE

Icariin Induces Osteoblast Differentiation and Mineralization without Dexamethasone in Vitro

(2013) Xiao-Ni Ma et al.   PLANTA MEDICA

Screening of flavonoids for effective osteoclastogenesis suppression

(2012) Yu-Wei Wu et al.   ANALYTICAL BIOCHEMISTRY

Antioxidants, like coenzyme Q10, selenite, and curcumin, inhibited osteoclast differentiation by suppressing reactive oxygen species generation

(2012) Ho-Jin Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Population pharmacokinetics of naringin in total flavonoids of Drynaria Fortunei (Kunze) J. Sm. in Chinese women with primary osteoporosis

(2012) Jian-nong Wang et al.   Chinese Journal of Integrative Medicine

The natural flavonoid galangin inhibits osteoclastic bone destruction and osteoclastogenesis by suppressing NF-κB in collagen-induced arthritis and bone marrow-derived macrophages

(2012) Jeong-Eun Huh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Vitamin E decreases bone mass by stimulating osteoclast fusion

(2012) Koji Fujita et al.   NATURE MEDICINE

Dietary anthocyanins protect endothelial cells against peroxynitrite-induced mitochondrial apoptosis pathway and Bax nuclear translocation: an in vitro approach

(2011) Joana Paixão et al.   APOPTOSIS

A novel flavonoid isolated from the steam-bark of Ulmus Wallichiana Planchon stimulates osteoblast function and inhibits osteoclast and adipocyte differentiation

(2011) Gaurav Swarnkar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP

(2011) Nadine Courtial et al.   FASEB JOURNAL

Anti-inflammatory Effects of Polyphenolic-Enriched Red Raspberry Extract in an Antigen-Induced Arthritis Rat Model

(2011) Dinorah Jean-Gilles et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of Liver X Receptor (LXR) Inhibits Receptor Activator of Nuclear Factor κB Ligand (RANKL)-induced Osteoclast Differentiation in an LXRβ-dependent Mechanism

(2011) Kirsten M. Robertson Remen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP)

(2011) Ya-Hui Chiu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Gymnasterkoreayne F inhibits osteoclast formation by suppressing NFATc1 and DC-STAMP expression

(2010) Hyun-Ju Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Associations between dietary flavonoid intakes and bone health in a scottish population

(2010) Antonia C Hardcastle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mangiferin attenuates osteoclastogenesis, bone resorption, and RANKL-induced activation of NF-κB and ERK

(2010) Estabelle Ang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2

(2010) Mei Xu et al.   Molecular Cancer

Anthocyanins: Natural Colorants with Health-Promoting Properties

(2010) Jian He et al.   Annual Review of Food Science and Technology

Cyanidin-3-Glucoside Reverses Ethanol-Induced Inhibition of Neurite Outgrowth: Role of Glycogen Synthase Kinase 3 Beta

(2009) Gang Chen et al.   NEUROTOXICITY RESEARCH

Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B

(2009) Andrea Dreiseitel et al.   PHARMACOLOGICAL RESEARCH

Dried Plum Polyphenols Inhibit Osteoclastogenesis by Downregulating NFATc1 and Inflammatory Mediators

(2008) So Young Bu et al.   CALCIFIED TISSUE INTERNATIONAL

Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation

(2007) Meiheng Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY