Genetic and epigenomic mechanisms of mammalian circadian transcription

Endocrine Effects of Circadian Disruption

(2016) Tracy A. Bedrosian et al.   Annual Review of Physiology

BMAL1 regulates transcription initiation and activates circadian clock gene expression in mammals

(2016) Wei Xiong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome

(2016) Alexey A. Soshnev et al.   MOLECULAR CELL

Circadian System and Glucose Metabolism: Implications for Physiology and Disease

(2016) Jingyi Qian et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Circadian Metabolism: From Mechanisms to Metabolomics and Medicine

(2016) Steven A. Brown   TRENDS IN ENDOCRINOLOGY AND METABOLISM

GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person

(2016) Youna Hu et al.   Nature Communications

Long-Range Chromosome Interactions Mediated by Cohesin Shape Circadian Gene Expression

(2016) Yichi Xu et al.   PLoS Genetics

Time for Food: The Intimate Interplay between Nutrition, Metabolism, and the Circadian Clock

(2015) Gad Asher et al.   CELL

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells

(2015) Brian J. Altman et al.   Cell Metabolism

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice

(2015) Dae-Hwan Kim et al.   HEPATOLOGY

Highly Efficient Genome Editing via CRISPR/Cas9 to Create Clock Gene Knockout Cells

(2015) Sandra Korge et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Fbxl11 Is a Novel Negative Element of the Mammalian Circadian Clock

(2015) Silke Reischl et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading

(2015) Bokai Zhu et al.   MOLECULAR CELL

PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription

(2015) Honglei Zhao et al.   MOLECULAR CELL

Histone monoubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback

(2015) Alfred G Tamayo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

Histone monoubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback

(2015) Alfred G Tamayo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Daily Variation in Global and Local DNA Methylation in Mouse Livers

(2015) Lin Xia et al.   PLoS One

Assembly of a Comprehensive Regulatory Network for the Mammalian Circadian Clock: A Bioinformatics Approach

(2015) Robert Lehmann et al.   PLoS One

Writing and reading H2B monoubiquitylation

(2014) Gilad Fuchs et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo

(2014) Bin Fang et al.   CELL

CLOCK:BMAL1 is a pioneer-like transcription factor

(2014) J. S. Menet et al.   GENES & DEVELOPMENT

Circadian expression profiles of chromatin remodeling factor genes in Arabidopsis

(2014) Hong Gil Lee et al.   JOURNAL OF PLANT RESEARCH

Specificity in Circadian Clock Feedback from Targeted Reconstitution of the NuRD Corepressor

(2014) Jin Young Kim et al.   MOLECULAR CELL

Phosphorylation of LSD1 by PKCα Is Crucial for Circadian Rhythmicity and Phase Resetting

(2014) Hye Jin Nam et al.   MOLECULAR CELL

Circadian behavior is light-reprogrammed by plastic DNA methylation

(2014) Abdelhalim Azzi et al.   NATURE NEUROSCIENCE

Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes

(2014) Hao A Duong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The PXDLS linear motif regulates circadian rhythmicity through protein–protein interactions

(2014) Moran Shalev et al.   NUCLEIC ACIDS RESEARCH

SRC-2 Is an Essential Coactivator for Orchestrating Metabolism and Circadian Rhythm

(2014) Erin Stashi et al.   Cell Reports

24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex

(2014) Andrew S. P. Lim et al.   PLoS Genetics

Neurospora WC-1 Recruits SWI/SNF to Remodel frequency and Initiate a Circadian Cycle

(2014) Bin Wang et al.   PLoS Genetics

Genome Architecture: Domain Organization of Interphase Chromosomes

(2013) Wendy A. Bickmore et al.   CELL

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

(2013) Matthew J Lyst et al.   NATURE NEUROSCIENCE

Cycles in spatial and temporal chromosomal organization driven by the circadian clock

(2013) Lorena Aguilar-Arnal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone methyltransferase MLL3 contributes to genome-scale circadian transcription

(2013) Utham K. Valekunja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery

(2013) L. Lande-Diner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Regions Flanking E-Box Binding Sites Influence DNA Binding Specificity of bHLH Transcription Factors through DNA Shape

(2013) Raluca Gordân et al.   Cell Reports

Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice

(2013) Kazuhiro Shimomura et al.   eLife

The essential role of cAMP/Ca2+signalling in mammalian circadian timekeeping

(2012) John S. O'Neill et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery

(2012) Benjamin D. Towbin et al.   CELL

Circadian Oscillations of Protein-Coding and Regulatory RNAs in a Highly Dynamic Mammalian Liver Epigenome

(2012) Christopher Vollmers et al.   Cell Metabolism

Diurnal expression ofDnmt3bmRNA in mouse liver is regulated by feeding and hepatic clockwork

(2012) Fumihiko Maekawa et al.   Epigenetics

Identification of a new clock-related element EL-box involved in circadian regulation by BMAL1/CLOCK and HES1

(2012) Taichi Ueshima et al.   GENE

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

Circadian Dbp Transcription Relies on Highly Dynamic BMAL1-CLOCK Interaction with E Boxes and Requires the Proteasome

(2012) Markus Stratmann et al.   MOLECULAR CELL

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

(2012) Yukimasa Takeda et al.   NUCLEIC ACIDS RESEARCH

Histone H2B monoubiquitination is required to reach maximal transcript levels of circadian clock genes in Arabidopsis

(2012) Kristiina Himanen et al.   PLANT JOURNAL

Ordered changes in histone modifications at the core of the Arabidopsis circadian clock

(2012) J. Malapeira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Genome-Wide RNA Polymerase II Profiles and RNA Accumulation Reveal Kinetics of Transcription and Associated Epigenetic Changes During Diurnal Cycles

(2012) Gwendal Le Martelot et al.   PLOS BIOLOGY

Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

(2012) Jerome S Menet et al.   eLife

Functional analysis of transcription factor binding sites in human promoters

(2012) Troy W Whitfield et al.   GENOME BIOLOGY

Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function

(2011) Maki Ukai-Tadenuma et al.   CELL

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

(2011) Jasmeen Oberoi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock

(2011) L. DiTacchio et al.   SCIENCE

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

A New Histone Code for Clocks?

(2011) S. A. Brown   SCIENCE

A Molecular Mechanism for Circadian Clock Negative Feedback

(2011) H. A. Duong et al.   SCIENCE

Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

(2011) Guillaume Rey et al.   PLOS BIOLOGY

Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock

(2010) Y. Lee et al.   JOURNAL OF CELL SCIENCE

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression

(2010) Sayako Katada et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Jumonji domain protein JMJD5 functions in both the plant and human circadian systems

(2010) M. A. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Throughput Characterization of Combinatorial Histone Codes

(2009) Nicolas L. Young et al.   MOLECULAR & CELLULAR PROTEOMICS

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL