Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology

(2015) Jason A. Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Behavioural and neural basis of anomalous motor learning in children with autism

(2015) Mollie K. Marko et al.   BRAIN

Attentional and sensory contributions to postural sway in children with autism spectrum disorder

(2015) John F. Stins et al.   GAIT & POSTURE

Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model

(2015) Sara Silva-Santos et al.   JOURNAL OF CLINICAL INVESTIGATION

Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders

(2015) Carlo Sala et al.   JOURNAL OF NEUROCHEMISTRY

From the genetic architecture to synaptic plasticity in autism spectrum disorder

(2015) Thomas Bourgeron   NATURE REVIEWS NEUROSCIENCE

Motor Learning and the Cerebellum

(2015) Chris I. De Zeeuw et al.   Cold Spring Harbor Perspectives in Biology

Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice

(2015) Michiel M. ten Brinke et al.   Cell Reports

Cerebellar associative sensory learning defects in five mouse autism models

(2015) Alexander D Kloth et al.   eLife

The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders

(2015) Matthew W. Mosconi et al.   Frontiers in Neuroscience

Cerebellar control of gait and interlimb coordination

(2014) María Fernanda Vinueza Veloz et al.   Brain Structure & Function

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism

(2014) Claire Piochon et al.   Nature Communications

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

(2014) Claire S. Leblond et al.   PLoS Genetics

Saccadic eye movement abnormalities in autism spectrum disorder indicate dysfunctions in cerebellum and brainstem

(2014) Lauren M Schmitt et al.   Molecular Autism

Early identification of autism spectrum disorders

(2013) Lonnie Zwaigenbaum et al.   BEHAVIOURAL BRAIN RESEARCH

Synaptic Transmission and Plasticity at Inputs to Murine Cerebellar Purkinje Cells Are Largely Dispensable for Standard Nonmotor Tasks

(2013) E. Galliano et al.   JOURNAL OF NEUROSCIENCE

Climbing Fiber Input Shapes Reciprocity of Purkinje Cell Firing

(2013) Aleksandra Badura et al.   NEURON

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Children with autism spectrum disorders show abnormal conditioned response timing on delay, but not trace, eyeblink conditioning

(2013) J. Oristaglio et al.   NEUROSCIENCE

Germline recombination by conditional gene targeting with Parvalbumin-Cre lines

(2013) Yohei Kobayashi et al.   Frontiers in Neural Circuits

Silencing the Majority of Cerebellar Granule Cells Uncovers Their Essential Role in Motor Learning and Consolidation

(2013) Elisa Galliano et al.   Cell Reports

Co-expression Profiling of Autism Genes in the Mouse Brain

(2013) Idan Menashe et al.   PLoS Computational Biology

SHANK1 Deletions in Males with Autism Spectrum Disorder

(2012) Daisuke Sato et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Autism-Associated Mutations in ProSAP2/Shank3 Impair Synaptic Transmission and Neurexin-Neuroligin-Mediated Transsynaptic Signaling

(2012) M. H. Arons et al.   JOURNAL OF NEUROSCIENCE

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism

(2012) S. J. Baudouin et al.   SCIENCE

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

(2012) Claire S. Leblond et al.   PLoS Genetics

Spatiotemporal firing patterns in the cerebellum

(2011) Chris I. De Zeeuw et al.   NATURE REVIEWS NEUROSCIENCE

Cerebellum Shapes Hippocampal Spatial Code

(2011) C. Rochefort et al.   SCIENCE

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

Intrinsic Plasticity Complements Long-Term Potentiation in Parallel Fiber Input Gain Control in Cerebellar Purkinje Cells

(2010) A. Belmeguenai et al.   JOURNAL OF NEUROSCIENCE

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

(2010) Simone Berkel et al.   NATURE GENETICS

Purkinje Cell-Specific Knockout of the Protein Phosphatase PP2B Impairs Potentiation and Cerebellar Motor Learning

(2010) M. Schonewille et al.   NEURON

The Role of the Cerebellum in Cognition and Emotion: Personal Reflections Since 1982 on the Dysmetria of Thought Hypothesis, and Its Historical Evolution from Theory to Therapy

(2010) Jeremy D. Schmahmann   NEUROPSYCHOLOGY REVIEW

βCaMKII controls the direction of plasticity at parallel fiber–Purkinje cell synapses

(2009) Geeske M van Woerden et al.   NATURE NEUROSCIENCE

Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning

(2009) Peer Wulff et al.   NATURE NEUROSCIENCE