The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders

Somatosensory cortex functional connectivity abnormalities in autism show opposite trends, depending on direction and spatial scale

(2015) Sheraz Khan et al.   BRAIN

Behavioural and neural basis of anomalous motor learning in children with autism

(2015) Mollie K. Marko et al.   BRAIN

Illuminating circuitry relevant to psychiatric disorders with optogenetics

(2015) Elizabeth E Steinberg et al.   CURRENT OPINION IN NEUROBIOLOGY

Individuals with autism spectrum disorder show abnormalities during initial and subsequent phases of precision gripping

(2015) Zheng Wang et al.   JOURNAL OF NEUROPHYSIOLOGY

Feedforward and Feedback Motor Control Abnormalities Implicate Cerebellar Dysfunctions in Autism Spectrum Disorder

(2015) M. W. Mosconi et al.   JOURNAL OF NEUROSCIENCE

Can Parents’ Concerns Predict Autism Spectrum Disorder? A Prospective Study of High-Risk Siblings From 6 to 36 Months of Age

(2015) Lori-Ann R. Sacrey et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Cerebellar associative sensory learning defects in five mouse autism models

(2015) Alexander D Kloth et al.   eLife

Chemogenetic Tools to Interrogate Brain Functions

(2014) Scott M. Sternson et al.   Annual Review of Neuroscience

Ameliorating effect of piperine on behavioral abnormalities and oxidative markers in sodium valproate induced autism in BALB/C mice

(2014) B. Pragnya et al.   BEHAVIOURAL BRAIN RESEARCH

Handedness as a marker of cerebral lateralization in children with and without autism

(2014) Gillian S. Forrester et al.   BEHAVIOURAL BRAIN RESEARCH

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

Clinical and genomic evaluation of 201 patients with Phelan–McDermid syndrome

(2014) Sara M. Sarasua et al.   HUMAN GENETICS

Prospective dynamic balance control during the swing phase of walking: Stability boundaries and time-to-contact analysis

(2014) J.G. Remelius et al.   HUMAN MOVEMENT SCIENCE

The Broader Autism Phenotype in Infancy: When Does It Emerge?

(2014) Sally Ozonoff et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

(2014) Shafali S. Jeste et al.   Nature Reviews Neurology

Contributions of the cerebellum and the motor cortex to acquisition and retention of motor memories

(2014) David J. Herzfeld et al.   NEUROIMAGE

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

Regional Alterations in Purkinje Cell Density in Patients with Autism

(2014) Jerry Skefos et al.   PLoS One

Autism Associated Gene, ENGRAILED2, and Flanking Gene Levels Are Altered in Post-Mortem Cerebellum

(2014) Jiyeon Choi et al.   PLoS One

Properties of bilateral spinocerebellar activation of cerebellar cortical neurons

(2014) Pontus Geborek et al.   Frontiers in Neural Circuits

Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism

(2014) Claire Piochon et al.   Nature Communications

Structural Growth Trajectories and Rates of Change in the First 3 Months of Infant Brain Development

(2014) Dominic Holland et al.   JAMA Neurology

Saccadic eye movement abnormalities in autism spectrum disorder indicate dysfunctions in cerebellum and brainstem

(2014) Lauren M Schmitt et al.   Molecular Autism

Stereological study of the neuronal number and volume of 38 brain subdivisions of subjects diagnosed with autism reveals significant alterations restricted to the striatum, amygdala and cerebellum

(2014) Jerzy Wegiel et al.   Acta Neuropathologica Communications

White Matter Microstructure and Atypical Visual Orienting in 7-Month-Olds at Risk for Autism

(2013) Jed T. Elison et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genetic Effects on Cerebellar Structure Across Mouse Models of Autism Using a Magnetic Resonance Imaging Atlas

(2013) Patrick E. Steadman et al.   Autism Research

The Interstitial Duplication 15q11.2-q13 Syndrome Includes Autism, Mild Facial Anomalies and a Characteristic EEG Signature

(2013) Nora Urraca et al.   Autism Research

A two-year longitudinal pilot MRI study of the brainstem in autism

(2013) Roger J. Jou et al.   BEHAVIOURAL BRAIN RESEARCH

Atypical basic movement kinematics in autism spectrum conditions

(2013) Jennifer L. Cook et al.   BRAIN

Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism

(2013) A. Jeremy Willsey et al.   CELL

Reorganization of Circuits Underlying Cerebellar Modulation of Prefrontal Cortical Dopamine in Mouse Models of Autism Spectrum Disorder

(2013) Tiffany D. Rogers et al.   CEREBELLUM

Chronic desipramine treatment rescues depression-related, social and cognitive deficits inEngrailed-2knockout mice

(2013) J. Brielmaier et al.   GENES BRAIN AND BEHAVIOR

Structural and functional underconnectivity as a negative predictor for language in autism

(2013) Marjolein Verly et al.   HUMAN BRAIN MAPPING

Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion

(2013) J Ellegood et al.   MOLECULAR PSYCHIATRY

Cerebellar Purkinje cell activity drives motor learning

(2013) T D Barbara Nguyen-Vu et al.   NATURE NEUROSCIENCE

Atypicalities in Cortical Structure, Handedness, and Functional Lateralization for Language in Autism Spectrum Disorders

(2013) Annukka K. Lindell et al.   NEUROPSYCHOLOGY REVIEW

Saccade adaptation in autism and Asperger’s disorder

(2013) B.P. Johnson et al.   NEUROSCIENCE

Children with autism spectrum disorders show abnormal conditioned response timing on delay, but not trace, eyeblink conditioning

(2013) J. Oristaglio et al.   NEUROSCIENCE

In utero exposure to valproic acid and autism — A current review of clinical and animal studies

(2013) Florence I. Roullet et al.   NEUROTOXICOLOGY AND TERATOLOGY

A Magnetic Resonance Imaging Study of Cerebellar Volume in Tuberous Sclerosis Complex

(2013) Neil I. Weisenfeld et al.   PEDIATRIC NEUROLOGY

Saccade Adaptation Abnormalities Implicate Dysfunction of Cerebellar-Dependent Learning Mechanisms in Autism Spectrum Disorders (ASD)

(2013) Matthew W. Mosconi et al.   PLoS One

Anticipatory Smooth Eye Movements in Autism Spectrum Disorder

(2013) Cordelia D. Aitkin et al.   PLoS One

Cerebellar networks with the cerebral cortex and basal ganglia

(2013) Andreea C. Bostan et al.   TRENDS IN COGNITIVE SCIENCES

Biological oscillations for learning walking coordination: dynamic recurrent neural network functionally models physiological central pattern generator

(2013) Thomas Hoellinger et al.   Frontiers in Computational Neuroscience

Co-expression Profiling of Autism Genes in the Mouse Brain

(2013) Idan Menashe et al.   PLoS Computational Biology

A 7T fMRI study of cerebellar activation in sequential finger movement tasks

(2013) M. R. Stefanescu et al.   EXPERIMENTAL BRAIN RESEARCH

Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency

(2013) Latha Soorya et al.   Molecular Autism

Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum

(2013) S J James et al.   Translational Psychiatry

Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction

(2013) Michele Cavallari et al.   NeuroImage-Clinical

Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion

(2012) Kimberly A. Aldinger et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Motor Learning Relies on Integrated Sensory Inputs in ADHD, but Over-Selectively on Proprioception in Autism Spectrum Conditions

(2012) Jun Izawa et al.   Autism Research

A complex of synaptic adhesion molecule CADM1, a molecule related to autism spectrum disorder, with MUPP1 in the cerebellum

(2012) Eriko Fujita et al.   JOURNAL OF NEUROCHEMISTRY

High-Level Gait Disorder: Associations with Specific White Matter Changes Observed on Advanced Diffusion Imaging

(2012) Michal Kafri et al.   JOURNAL OF NEUROIMAGING

A Stochastic Signaling Network Mediates the Probabilistic Induction of Cerebellar Long-Term Depression

(2012) G. Antunes et al.   JOURNAL OF NEUROSCIENCE

Cerebellar Contributions to Reach Adaptation and Learning Sensory Consequences of Action

(2012) J. Izawa et al.   JOURNAL OF NEUROSCIENCE

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex

(2012) R. Michelle Reith et al.   NEUROBIOLOGY OF DISEASE

Direct visualization of cerebellar nuclei in patients with focal cerebellar lesions and its application for lesion-symptom mapping

(2012) S. Maderwald et al.   NEUROIMAGE

Autism-Relevant Social Abnormalities and Cognitive Deficits in Engrailed-2 Knockout Mice

(2012) Jennifer Brielmaier et al.   PLoS One

Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism

(2012) S. J. Baudouin et al.   SCIENCE

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Atypical lateralization of ERP response to native and non-native speech in infants at risk for autism spectrum disorder

(2012) Anne M. Seery et al.   Developmental Cognitive Neuroscience

Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: Initial studies and future directions

(2011) Michelle D. Carter et al.   Autism Research

Differences in saccade dynamics between spinocerebellar ataxia 2 and late-onset cerebellar ataxias

(2011) P. Federighi et al.   BRAIN

Cerebellar Zones: History, Development, and Function

(2011) John Oberdick et al.   CEREBELLUM

Consensus Paper: Roles of the Cerebellum in Motor Control—The Diversity of Ideas on Cerebellar Involvement in Movement

(2011) Mario Manto et al.   CEREBELLUM

Spectrum of neurodevelopmental disabilities in children with cerebellar malformations

(2011) MARIE-EVE BOLDUC et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Segregated and overlapping neural circuits exist for the production of static and dynamic precision grip force

(2011) Kristina A. Neely et al.   HUMAN BRAIN MAPPING

Evidence for a motor somatotopy in the cerebellar dentate nucleus-An FMRI study in humans

(2011) Michael Küper et al.   HUMAN BRAIN MAPPING

Transcranial magnetic stimulation and motor plasticity in human lateral cerebellum: Dual effect on saccadic adaptation

(2011) Muriel Panouillères et al.   HUMAN BRAIN MAPPING

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Human Basal Ganglia and the Dynamic Control of Force during On-Line Corrections

(2011) S. T. Grafton et al.   JOURNAL OF NEUROSCIENCE

Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning

(2011) J. H. Freeman et al.   LEARNING & MEMORY

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Spatiotemporal firing patterns in the cerebellum

(2011) Chris I. De Zeeuw et al.   NATURE REVIEWS NEUROSCIENCE

Specific cerebellar regions are related to force amplitude and rate of force development

(2011) M.B. Spraker et al.   NEUROIMAGE

Incidence and anatomy of gaze-evoked nystagmus in patients with cerebellar lesions

(2011) B. Baier et al.   NEUROLOGY

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Lesions of the dentate and interposed nuclei are associated with impaired prehension in cerebellar patients

(2011) M. Küper et al.   NEUROSCIENCE LETTERS

Connecting the dots of the cerebro-cerebellar role in cognitive function: Neuronal pathways for cerebellar modulation of dopamine release in the prefrontal cortex

(2011) Tiffany D. Rogers et al.   SYNAPSE

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

Prader-Willi syndrome and Angelman syndrome

(2010) Karin Buiting   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Neurobehavioral Abnormalities in First-Degree Relatives of Individuals With Autism

(2010) Matthew W. Mosconi et al.   ARCHIVES OF GENERAL PSYCHIATRY

Connecting Genes to Brain in the Autism Spectrum Disorders

(2010) Brett S. Abrahams et al.   ARCHIVES OF NEUROLOGY

Impairment of social and emotional behaviors in Cadm1-knockout mice

(2010) Yuki Takayanagi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Brain Region-Specific Changes in Oxidative Stress and Neurotrophin Levels in Autism Spectrum Disorders (ASD)

(2010) Elizabeth M. Sajdel-Sulkowska et al.   CEREBELLUM

Greater Disruption to Control of Voluntary Saccades in Autistic Disorder than Asperger’s Disorder: Evidence for Greater Cerebellar Involvement in Autism?

(2010) Chloe Stanley-Cary et al.   CEREBELLUM

Family-based association study of ITGB3 in autism spectrum disorder and its endophenotypes

(2010) Valerio Napolioni et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Decreased static and dynamic postural control in children with autism spectrum disorders

(2010) Kimberly A. Fournier et al.   GAIT & POSTURE

A Diffusion Tensor Imaging Study of the Cerebellar Pathways in Children With Autism Spectrum Disorder

(2010) Lalitha Sivaswamy et al.   JOURNAL OF CHILD NEUROLOGY

Cerebellar Modules: Individual or Composite Entities?

(2010) N. L. Cerminara   JOURNAL OF NEUROSCIENCE

White Matter Compromise of Callosal and Subcortical Fiber Tracts in Children With Autism Spectrum Disorder: A Diffusion Tensor Imaging Study

(2010) Dinesh K. Shukla et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Atypical development of white matter microstructure in adolescents with autism spectrum disorders

(2010) Yawei Cheng et al.   NEUROIMAGE

Newborn infants learn during sleep

(2010) W. P. Fifer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological and Focal Cerebellar Substrates of Abnormal Postural Sway and Tremor in Alcoholic Women

(2009) Edith V. Sullivan et al.   BIOLOGICAL PSYCHIATRY

Anatomical correlates of ocular motor deficits in cerebellar lesions

(2009) B. Baier et al.   BRAIN

Decreased connectivity and cerebellar activity in autism during motor task performance

(2009) S. H. Mostofsky et al.   BRAIN

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

(2009) Jin Nakatani et al.   CELL

Increase in Cerebellar Neurotrophin-3 and Oxidative Stress Markers in Autism

(2009) Elizabeth M. Sajdel-Sulkowska et al.   CEREBELLUM

Predictive Motor Timing Performance Dissociates Between Early Diseases of the Cerebellum and Parkinson's Disease

(2009) Martin Bareš et al.   CEREBELLUM

Segregated Fronto-Cerebellar Circuits Revealed by Intrinsic Functional Connectivity

(2009) Fenna M. Krienen et al.   CEREBRAL CORTEX

Neurodevelopmental outcomes in children with cerebellar malformations: a systematic review

(2009) MARIE-EVE BOLDUC et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Gaze fixation deficits and their implication in ataxia-telangiectasia

(2009) A G Shaikh et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cerebellar Contributions to Adaptive Control of Saccades in Humans

(2009) M. Xu-Wilson et al.   JOURNAL OF NEUROSCIENCE

Distinct Cerebellar Contributions to Intrinsic Connectivity Networks

(2009) C. Habas et al.   JOURNAL OF NEUROSCIENCE

Density of cerebellar basket and stellate cells in autism: Evidence for a late developmental loss of Purkinje cells

(2009) Elizabeth R. Whitney et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Representation of internal models of action in the autistic brain

(2009) Courtney C Haswell et al.   NATURE NEUROSCIENCE

Cerebellar Injury in Term Infants: Clinical Characteristics, Magnetic Resonance Imaging Findings, and Outcome

(2009) Catherine Limperopoulos et al.   PEDIATRIC NEUROLOGY

Impaired inhibitory control is associated with higher-order repetitive behaviors in autism spectrum disorders

(2009) M. W. Mosconi et al.   PSYCHOLOGICAL MEDICINE

A Pilot Study: Coordination of Precision Grip in Children and Adolescents with High Functioning Autism

(2009) Fabian J. David et al.   Pediatric Physical Therapy

Effects of Second-Generation Antipsychotic Medication on Smooth Pursuit Performance in Antipsychotic-Naive Schizophrenia

(2008) Rebekka Lencer et al.   ARCHIVES OF GENERAL PSYCHIATRY

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome.

(2008) Caitlyn H. McNaughton et al.   BEHAVIORAL NEUROSCIENCE

Mutations in the gene encoding CADM1 are associated with autism spectrum disorder

(2008) Yu Zhiling et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acquisition of internal models of motor tasks in children with autism

(2008) Jennifer C. Gidley Larson et al.   BRAIN

The Autistic Neuron: Troubled Translation?

(2008) Raymond J. Kelleher et al.   CELL

Separate Neural Substrates in the Human Cerebellum for Sensory-motor Adaptation of Reactive and of Scanning Voluntary Saccades

(2008) N. Alahyane et al.   CEREBELLUM

Cerebellar Purkinje Cells are Reduced in a Subpopulation of Autistic Brains: A Stereological Experiment Using Calbindin-D28k

(2008) Elizabeth R. Whitney et al.   CEREBELLUM

Social approach in genetically engineered mouse lines relevant to autism

(2008) S. S. Moy et al.   GENES BRAIN AND BEHAVIOR

Adaptive Control of Saccades via Internal Feedback

(2008) H. Chen-Harris et al.   JOURNAL OF NEUROSCIENCE

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Control of mental activities by internal models in the cerebellum

(2008) Masao Ito   NATURE REVIEWS NEUROSCIENCE

Altered cerebellar feedback projections in Asperger syndrome

(2008) Marco Catani et al.   NEUROIMAGE

SUPPRESSION OF SACCADIC INTRUSIONS IN HEREDITARY ATAXIA BY MEMANTINE

(2008) A. Serra et al.   NEUROLOGY

A model of the olivo-cerebellar system as a temporal pattern generator

(2008) Gilad A. Jacobson et al.   TRENDS IN NEUROSCIENCES

Timing and plasticity in the cerebellum: focus on the granular layer

(2008) Egidio D’Angelo et al.   TRENDS IN NEUROSCIENCES

Planning actions in autism

(2008) Maddalena Fabbri-Destro et al.   EXPERIMENTAL BRAIN RESEARCH

Towards a neuroanatomy of autism: A systematic review and meta-analysis of structural magnetic resonance imaging studies

(2007) Andrew C. Stanfield et al.   EUROPEAN PSYCHIATRY

IncreasedGAD67 mRNA expression in cerebellar interneurons in autism: Implications for Purkinje cell dysfunction

(2007) Jane Yip et al.   JOURNAL OF NEUROSCIENCE RESEARCH