MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression

MicroRNA-124 links p53 to the NF-κB pathway in B-cell lymphomas

(2015) D Jeong et al.   LEUKEMIA

Treatment with 4-Methylpyrazole Modulated Stellate Cells and Natural Killer Cells and Ameliorated Liver Fibrosis in Mice

(2015) Hyon-Seung Yi et al.   PLoS One

miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program

(2015) Shicheng Su et al.   Nature Communications

MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic plate-derived mesenchymal stem cells

(2015) Jeongeun Hyun et al.   Scientific Reports

Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR

(2015) Ewa Wunsch et al.   Journal of Immunology Research

Temporal trends in population-based death rates associated with chronic liver disease and liver cancer in the United States over the last 30 years

(2014) Yuhree Kim et al.   CANCER

Deficiency of Cardiomyocyte-specific MicroRNA-378 Contributes to the Development of Cardiac Fibrosis Involving a Transforming Growth Factor β (TGFβ1)-dependent Paracrine Mechanism

(2014) Raghu S. Nagalingam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway

(2014) Xiaolong Tu et al.   JOURNAL OF PATHOLOGY

Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever

(2014) Vinicio Carloni et al.   LIVER INTERNATIONAL

A Genetic Variant in Primary miR-378 Is Associated with Risk and Prognosis of Hepatocellular Carcinoma in a Chinese Population

(2014) Jiaze An et al.   PLoS One

Hepatic-specific activation of peroxisome proliferator-activated receptor γ coactivator-1β protects against steatohepatitis

(2013) Elena Bellafante et al.   HEPATOLOGY

Hepatic stellate cells in liver development, regeneration, and cancer

(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

In Vivo Gene Delivery with l-Tyrosine Polyphosphate Nanoparticles

(2013) Andrew J. Ditto et al.   MOLECULAR PHARMACEUTICS

Diversifying microRNA sequence and function

(2013) Stefan L. Ameres et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Potential Role of Hedgehog Pathway in Liver Response to Radiation

(2013) Sihyung Wang et al.   PLoS One

Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma

(2012) I. S. Chan et al.   CANCER RESEARCH

Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

(2012) Yuping Chen et al.   GASTROENTEROLOGY

Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation

(2012) Guanhua Xie et al.   GUT

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans

(2012) James Pritchett et al.   HEPATOLOGY

CD11b+Gr1+bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice

(2012) Yang-Gun Suh et al.   HEPATOLOGY

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rno-miR-34 family is upregulated and targets ACSL1 in dimethylnitrosamine-induced hepatic fibrosis in rats

(2011) Wei-Qing Li et al.   FEBS Journal

Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice

(2011) Wenxiu Zhao et al.   INTERNATIONAL JOURNAL OF CANCER

Cellular interactions with biodegradable polyurethanes formulated from L-tyrosine

(2011) Parth N Shah et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Increased production of sonic hedgehog by ballooned hepatocytes

(2011) Fatima Rangwala et al.   JOURNAL OF PATHOLOGY

Cross-Platform Comparison of Microarray-Based Multiple-Class Prediction

(2011) Xiaohui Fan et al.   PLoS One

Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

(2011) George M. Philips et al.   PLoS One

MicroRNAs in NF- B signaling

(2011) X. Ma et al.   Journal of Molecular Cell Biology

MicroRNA: Biogenesis, Function and Role in Cancer

(2010) Leigh-Ann MacFarlane et al.   CURRENT GENOMICS

Signals from dying hepatocytes trigger growth of liver progenitors

(2010) Y. Jung et al.   GUT

The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis

(2010) Mustafa S. Ascha et al.   HEPATOLOGY

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

(2010) Christoph Roderburg et al.   HEPATOLOGY

The role of Hedgehog signaling in fibrogenic liver repair

(2010) Steve S. Choi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hedgehog signaling in the liver

(2010) Alessia Omenetti et al.   JOURNAL OF HEPATOLOGY

Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis and hepatocellular carcinoma

(2010) Thiago de Almeida Pereira et al.   LABORATORY INVESTIGATION

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

(2009) Steve S. Choi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

(2009) Thomas Amann et al.   CANCER SCIENCE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Blends of novel L-tyrosine-based polyurethanes and polyphosphate for potential biomedical applications

(2009) Parth N. Shah et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Nanomedicine based approaches for the delivery of siRNA in cancer

(2009) B. Ozpolat et al.   JOURNAL OF INTERNAL MEDICINE

Nanospheres Formulated froml-Tyrosine Polyphosphate Exhibiting Sustained Release of Polyplexes and In Vitro Controlled Transfection Properties

(2009) Andrew J. Ditto et al.   MOLECULAR PHARMACEUTICS

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Cell Type–Dependent Pro- and Anti-Inflammatory Role of Signal Transducer and Activator of Transcription 3 in Alcoholic Liver Injury

(2008) Norio Horiguchi et al.   GASTROENTEROLOGY

Liver Cell–Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

(2008) Rafal P. Witek et al.   GASTROENTEROLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

(2007) Liu Yang et al.   JOURNAL OF HEPATOLOGY

Real-time PCR quantification of precursor and mature microRNA

(2007) Thomas D. Schmittgen et al.   METHODS