Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth

HIF-2alpha-dependent PAI-1 induction contributes to angiogenesis in hepatocellular carcinoma

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Synovial Sarcoma: Recent Discoveries as a Roadmap to New Avenues for Therapy

(2015) Torsten O. Nielsen et al.   Cancer Discovery

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(2014) Mark Linch et al.   Nature Reviews Clinical Oncology

DNMT3a epigenetic program regulates the HIF-2  oxygen-sensing pathway and the cellular response to hypoxia

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hsBAFF promotes proliferation and survival in cultured B lymphocytes via calcium signaling activation of mTOR pathway

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The evolving classification of soft tissue tumours - an update based on the new 2013 WHO classification

(2013) Christopher D M Fletcher   HISTOPATHOLOGY

Hypoxia-Inducible Factor-1  Causes Renal Cyst Expansion through Calcium-Activated Chloride Secretion

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Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

(2013) Adrian Britschgi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis

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Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway

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Systematic identification of genomic markers of drug sensitivity in cancer cells

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Expression Profiling of Liposarcoma Yields a Multigene Predictor of Patient Outcome and Identifies Genes That Contribute to Liposarcomagenesis

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Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1  Expression in an AhR-Independent Fashion

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Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors

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An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

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HIF-2  deletion promotes Kras-driven lung tumor development

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Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma

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Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

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Histone Deacetylase Inhibitors Reverse SS18-SSX-Mediated Polycomb Silencing of the Tumor Suppressor Early Growth Response 1 in Synovial Sarcoma

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Differential Dependence of Hypoxia-inducible Factors 1α and 2α on mTORC1 and mTORC2

(2008) Alfredo Toschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MFH revisited: outcome after surgical treatment of undifferentiated pleomorphic or not otherwise specified (NOS) sarcomas of the extremities—an analysis of 140 patients

(2008) Marcus Lehnhardt et al.   LANGENBECKS ARCHIVES OF SURGERY

HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen

(2008) N. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

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