Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

The Split-Apply-Combine Strategy for Data Analysis

(2015) Hadley Wickham   Journal of Statistical Software

Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors

(2012) Satish Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibition of Ca2+-activated Cl− channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma

(2012) Wen Liu et al.   CANCER LETTERS

TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression

(2012) U. Duvvuri et al.   CANCER RESEARCH

Tumor Epidermal Growth Factor Receptor and EGFR PY1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma

(2012) S. Wheeler et al.   CLINICAL CANCER RESEARCH

Trpc1 Ion Channel Modulates Phosphatidylinositol 3-Kinase/Akt Pathway during Myoblast Differentiation and Muscle Regeneration

(2012) Nadège Zanou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The molecular pathogenesis of head and neck squamous cell carcinoma

(2012) S. Michael Rothenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidermal growth factor chronically upregulates Ca2+-dependent Cl−conductance and TMEM16A expression in intestinal epithelial cells

(2012) Magdalena S. Mroz et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

(2012) Hawon Cho et al.   NATURE NEUROSCIENCE

Enhanced Expression of ANO1 in Head and Neck Squamous Cell Carcinoma Causes Cell Migration and Correlates with Poor Prognosis

(2012) Christian Ruiz et al.   PLoS One

Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network

(2012) P. Perez-Cornejo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Phosphatidylinositol-3-Kinase Pathway in Head and Neck Squamous Cell Carcinoma

(2012) Li Du et al.   Journal of Oncology

Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS

(2011) Shampa Chatterjee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Characterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours

(2011) Karolina Holm et al.   BREAST CANCER RESEARCH AND TREATMENT

Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

(2011) Eric T. Sawey et al.   CANCER CELL

Examining the role of cyclin D1 in breast cancer

(2011) Marco A Velasco-Velázquez et al.   Future Oncology

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer

(2011) Charles C. Chung et al.   HUMAN MOLECULAR GENETICS

CaM Kinase control of AKT and LNCaP cell survival

(2011) John M. Schmitt et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines

(2010) C Ayoub et al.   BRITISH JOURNAL OF CANCER

The Src, Syk, and Tec family kinases: Distinct types of molecular switches

(2010) J. Michael Bradshaw   CELLULAR SIGNALLING

Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase

(2010) E. Cipolletta et al.   ENDOCRINOLOGY

TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

(2010) Wan Namkung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

QPatch: The Missing Link Between HTS and Ion Channel Drug Discovery

(2009) Yi Liu et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

UA62784, a novel inhibitor of centromere protein E kinesin-like protein

(2009) M. C. Henderson et al.   MOLECULAR CANCER THERAPEUTICS

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Prognostic Significance of Epidermal Growth Factor Receptor Phosphorylation and Mutation in Head and Neck Squamous Cell Carcinoma

(2009) T. Hama et al.   ONCOLOGIST

EGF mediates calcium-activated chloride channel activation in the human bronchial epithelial cell line 16HBE14o−: involvement of tyrosine kinase p60c-src

(2008) Claudette Jeulin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

Ca2+/Calmodulin-dependent Protein Kinases

(2008) M. T. Swulius et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic Therapy

(2008) A. Arcangeli et al.   CURRENT MEDICINAL CHEMISTRY

Distinctive clinicopathological associations of amplification of thecortactingene at 11q13 in head and neck squamous cell carcinomas

(2008) JP Rodrigo et al.   JOURNAL OF PATHOLOGY

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE