Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

Comparative effects of overproducing the AraC-type transcriptional regulators MarA, SoxS, RarA and RamA on antimicrobial drug susceptibility inKlebsiella pneumoniae

(2016) Juan-Carlos Jiménez-Castellanos et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Probing substrate binding to the metal binding sites in metallo-β-lactamase L1 during catalysis

(2016) Mahesh Aitha et al.   MedChemComm

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

(2015) Jürgen Brem et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Overcoming differences: The catalytic mechanism of metallo-β-lactamases

(2015) María-Rocío Meini et al.   FEBS LETTERS

A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens

(2015) Karen Bush   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1

(2015) Jürgen Brem et al.   Chemical Science

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy

(2014) Anna M. Rydzik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Penicillin-binding proteins: evergreen drug targets

(2014) Jean-Marie Frère et al.   CURRENT OPINION IN PHARMACOLOGY

Molecular basis of non-mutational derepression of ramA in Klebsiella pneumoniae

(2014) Shyamasree De Majumdar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins

(2014) Han Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A variety of roles for versatile zinc in metallo-β-lactamases

(2014) A. I. Karsisiotis et al.   Metallomics

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

(2014) Jürgen Brem et al.   Nature Chemistry

Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3

(2013) Sander S. van Berkel et al.   ACS Chemical Biology

Assay Platform for Clinically Relevant Metallo-β-lactamases

(2013) Sander S. van Berkel et al.   JOURNAL OF MEDICINAL CHEMISTRY

A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

(2011) Steven R. Inglis et al.   ANALYTICAL BIOCHEMISTRY

Analysis of the Functional Contributions of Asn233 in Metallo-β-Lactamase IMP-1

(2011) Nicholas G. Brown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic regulation of the ramA locus and its expression in clinical isolates of Klebsiella pneumoniae

(2011) R. Rosenblum et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70

(2010) Lionel Vercheval et al.   BIOCHEMICAL JOURNAL

Crystal Structures of Covalent Complexes of β-Lactam Antibiotics withEscherichia coliPenicillin-Binding Protein 5: Toward an Understanding of Antibiotic Specificity

(2010) George Nicola et al.   BIOCHEMISTRY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a New Metallo- -Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

(2009) D. Yong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Critical Role of Tryptophan 154 for the Activity and Stability of Class D β-Lactamases,

(2009) Stéphane Baurin et al.   BIOCHEMISTRY

Crystal Structures of Complexes of Bacterial dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle

(2008) Eric Sauvage et al.   JOURNAL OF MOLECULAR BIOLOGY