Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy

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Accurate design of co-assembling multi-component protein nanomaterials

(2014) Neil P. King et al.   NATURE

Proliferation and significance of clinically relevant β-lactamases

(2013) Karen Bush   Annals of the New York Academy of Sciences

Solution structures of theBacillus cereusmetallo-β-lactamase BcII and its complex with the broad spectrum inhibitorR-thiomandelic acid

(2013) Andreas Ioannis Karsisiotis et al.   BIOCHEMICAL JOURNAL

Metallo-β-lactamase: Inhibitors and reporter substrates

(2013) Walter Fast et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

19F NMR: a valuable tool for studying biological events

(2013) Han Chen et al.   CHEMICAL SOCIETY REVIEWS

Chromophore-Linked Substrate (CLS405): Probing Metallo-β-Lactamase Activity and Inhibition

(2013) Anne Makena et al.   ChemMedChem

Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination

(2013) George G. Zhanel et al.   DRUGS

Antibiotics in the clinical pipeline in 2013

(2013) Mark S Butler et al.   JOURNAL OF ANTIBIOTICS

Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases

(2013) David E. Ehmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assay Platform for Clinically Relevant Metallo-β-lactamases

(2013) Sander S. van Berkel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Insights into the Subclass B3 Metallo-β-Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo-β-Lactamase Inhibitor Mercaptoacetate

(2012) Jun-ichi Wachino et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation

(2012) Tihomir Tomašić et al.   Expert Opinion on Drug Discovery

New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition

(2012) Dustin T. King et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of New Drugs for an Old Target — The Penicillin Binding Proteins

(2012) Astrid Zervosen et al.   MOLECULES

Rhodanine carboxylic acids as novel inhibitors of histone acetyltransferases

(2012) Silviya D. Furdas et al.   MedChemComm

Privileged Scaffolds or Promiscuous Binders: A Comparative Study on Rhodanines and Related Heterocycles in Medicinal Chemistry

(2011) Thomas Mendgen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metallo-β-lactamases: a last frontier for β-lactams?

(2011) Giuseppe Cornaglia et al.   LANCET INFECTIOUS DISEASES

Privileged scaffolds for library design and drug discovery

(2010) Matthew E Welsch et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bridging cell wall biosynthesis and bacterial morphogenesis

(2010) Pierre-Jean Matteï et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Current Challenges in Antimicrobial Chemotherapy

(2010) Carine Bebrone et al.   DRUGS

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rhodanine as a Privileged Scaffold in Drug Discovery

(2009) T. Tomasic et al.   CURRENT MEDICINAL CHEMISTRY

The Mechanisms of Catalysis by Metallo -Lactamases

(2008) Michael I. Page et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS