Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity

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Profiling peripheral microRNAs in obesity and type 2 diabetes mellitus

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NRG4: An Endocrine Link between Brown Adipose Tissue and Liver

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Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

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Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance

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Plasma Exosome MicroRNA Profiling Unravels a New Potential Modulator of Adiponectin Pathway in Diabetes: Effect of Glycemic Control

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Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

(2014) Thorsten Gnad et al.   NATURE

The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis

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Circulating Exosomal microRNAs as Biomarkers of Colon Cancer

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Phenotypic Characterization of miR-92a−/− Mice Reveals an Important Function of miR-92a in Skeletal Development

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MicroRNA-378 controls classical brown fat expansion to counteract obesity

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An endocrine role for brown adipose tissue?

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Identification of miR-106b-93 as a negative regulator of brown adipocyte differentiation

(2013) Yan Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Turning WAT into BAT: a review on regulators controlling the browning of white adipocytes

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The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

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A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Inhibition of MicroRNA-92a Prevents Endothelial Dysfunction and Atherosclerosis in Mice

(2013) Xavier Loyer et al.   CIRCULATION RESEARCH

Increased cGMP promotes healthy expansion and browning of white adipose tissue

(2013) Michaela M. Mitschke et al.   FASEB JOURNAL

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

Brown and beige fat: development, function and therapeutic potential

(2013) Matthew Harms et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans

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Serum Circulating microRNA Profiling for Identification of Potential Type 2 Diabetes and Obesity Biomarkers

(2013) Nuria Pescador et al.   PLoS One

MicroRNA networks regulate development of brown adipocytes

(2013) Mirko Trajkovski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit

(2013) Yong Chen et al.   Nature Communications

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

(2013) Irina G. Shabalina et al.   Cell Reports

Inhibition of miR-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury

(2012) Claudio Iaconetti et al.   BASIC RESEARCH IN CARDIOLOGY

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Systemic  -Adrenergic Stimulation of Thermogenesis Is Not Accompanied by Brown Adipose Tissue Activity in Humans

(2012) M. J. Vosselman et al.   DIABETES

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

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MyomiR-133 regulates brown fat differentiation through Prdm16

(2012) Mirko Trajkovski et al.   NATURE CELL BIOLOGY

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

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Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells

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Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

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Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity

(2011) Pernille Keller et al.   BMC Endocrine Disorders

Estrogen Receptor β1 Expression Is Regulated by miR-92 in Breast Cancer

(2010) Hakeemah Al-Nakhle et al.   CANCER RESEARCH

Human Brown Adipose Tissue

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Distribution and Development of Brown Adipocytes in the Murine and Human Adipose Organ

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Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

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Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development

(2010) Masatoshi Shigoka et al.   PATHOLOGY INTERNATIONAL

Pharmacological potential of RNAi — Focus on miRNA

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High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

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Functional Brown Adipose Tissue in Healthy Adults

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Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Down-Regulation of miR-92 in Human Plasma Is a Novel Marker for Acute Leukemia Patients

(2009) Masami Tanaka et al.   PLoS One

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Protein Kinase G Controls Brown Fat Cell Differentiation and Mitochondrial Biogenesis

(2009) B. Haas et al.   Science Signaling

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130

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