RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer

Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association

(2015) Anthony Martin et al.   BONE

Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion

(2015) Gillian Browne et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1

(2014) Bertrade C. Mbom et al.   MOLECULAR BIOLOGY OF THE CELL

Expression of RUNX1 Correlates with Poor Patient Prognosis in Triple Negative Breast Cancer

(2014) Nicola Ferrari et al.   PLoS One

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

Wnt/Catenin Signaling in Adult Stem Cell Physiology and Disease

(2014) Alexander Ring et al.   Stem Cell Reviews and Reports

Concise Review: Breast Cancer Stem Cells: Regulatory Networks, Stem Cell Niches, and Disease Relevance

(2014) Wenjun Guo   Stem Cells Translational Medicine

β-catenin at the centrosome

(2013) Bertrade C. Mbom et al.   BIOESSAYS

Wnt signaling in stem and cancer stem cells

(2013) Jane D Holland et al.   CURRENT OPINION IN CELL BIOLOGY

A new genome-driven integrated classification of breast cancer and its implications

(2013) Sarah-Jane Dawson et al.   EMBO JOURNAL

Tankyrases as drug targets

(2013) Lari Lehtiö et al.   FEBS Journal

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis

(2013) X Lu et al.   ONCOGENE

Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex

(2012) Vivian S.W. Li et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

RUNX3 interactome reveals novel centrosomal targeting of RUNX family of transcription factors

(2012) Linda Shyue Huey Chuang et al.   CELL CYCLE

Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland

(2012) Renée van Amerongen et al.   Cell Stem Cell

Cooperating transcription factors mediate the function of estrogen receptor

(2012) Elisa Fiorito et al.   CHROMOSOMA

Runx1: no longer just for leukemia

(2012) Ichiro Taniuchi et al.   EMBO JOURNAL

Sequence analysis of mutations and translocations across breast cancer subtypes

(2012) Shantanu Banerji et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The RUNX family in breast cancer: relationships with estrogen signaling

(2012) N-O Chimge et al.   ONCOGENE

Wnt Signaling in Mammary Glands: Plastic Cell Fates and Combinatorial Signaling

(2012) C. M. Alexander et al.   Cold Spring Harbor Perspectives in Biology

The  -Catenin Destruction Complex

(2012) J. L. Stamos et al.   Cold Spring Harbor Perspectives in Biology

RUNX1 and its understudied role in breast cancer

(2011) Kevin A. Janes   CELL CYCLE

Opposing Effects of Runx2 and Estradiol on Breast Cancer Cell Proliferation: In Vitro Identification of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness

(2011) N.-O. Chimge et al.   CLINICAL CANCER RESEARCH

Phosphorylated β-catenin localizes to centrosomes of neuronal progenitors and is required for cell polarity and neurogenesis in developing midbrain

(2011) Dmitri Chilov et al.   DEVELOPMENTAL BIOLOGY

AP-2γ regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription

(2011) Si Kee Tan et al.   EMBO JOURNAL

Estrogen Carcinogenesis in Breast Cancer

(2011) Doris Germain   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion

(2011) Gillian H. Little et al.   NUCLEIC ACIDS RESEARCH

RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

(2011) B Huang et al.   ONCOGENE

Sox2 expression in breast tumours and activation in breast cancer stem cells

(2011) O Leis et al.   ONCOGENE

Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression

(2011) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression

(2011) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Runx2 in normal tissues and cancer cells: A developing story

(2010) Karen Blyth et al.   BLOOD CELLS MOLECULES AND DISEASES

Metastatic bone disease: Role of transcription factors and future targets

(2010) Jitesh Pratap et al.   BONE

Genome-Wide Analysis of Estrogen Receptor   DNA Binding and Tethering Mechanisms Identifies Runx1 as a Novel Tethering Factor in Receptor-Mediated Transcriptional Activation

(2010) J. D. Stender et al.   MOLECULAR AND CELLULAR BIOLOGY

Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

(2010) Sanjeev K Baniwal et al.   Molecular Cancer

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

RUNX3 is multifunctional in carcinogenesis of multiple solid tumors

(2010) L S H Chuang et al.   ONCOGENE

Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines

(2010) Mitsutaka Kadota et al.   PLoS One

Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of Metastasis

(2010) Paola Marcato et al.   STEM CELLS

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

(2009) Willem-Jan Welboren et al.   EMBO JOURNAL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

MMTV-Wnt1 and -ΔN89β-Catenin Induce Canonical Signaling in Distinct Progenitors and Differentially Activate Hedgehog Signaling within Mammary Tumors

(2009) Brigitte Teissedre et al.   PLoS One

Modulation of Runx2 Activity by Estrogen Receptor-α: Implications for Osteoporosis and Breast Cancer

(2008) Omar Khalid et al.   ENDOCRINOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY