Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

(2016) Cecilia Li et al.   Scientific Reports

Model-driven mapping of transcriptional networks reveals the circuitry and dynamics of virulence regulation

(2015) Ezekiel J. Maier et al.   GENOME RESEARCH

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans

(2015) Kwang-Woo Jung et al.   Nature Communications

Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans

(2015) Hanhae Kim et al.   Scientific Reports

Retromer Is Essential for Autophagy-Dependent Plant Infection by the Rice Blast Fungus

(2015) Wenhui Zheng et al.   PLoS Genetics

A role for TOR complex 2 signaling in promoting autophagy

(2014) Ariadne Vlahakis et al.   Autophagy

Literature-Based Gene Curation and Proposed Genetic Nomenclature for Cryptococcus

(2014) Diane O. Inglis et al.   EUKARYOTIC CELL

The vacuolar-sorting protein Snf7 is required for export of virulence determinants in members of the Cryptococcus neoformans complex.

(2014) Rodrigo M. da C. Godinho et al.   Scientific Reports

Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation

(2014) Guilhem Janbon et al.   PLoS Genetics

The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication

(2013) Mathias Rask-Andersen et al.   Annual Review of Pharmacology and Toxicology

Role of Retrograde Trafficking in Stress Response, Host Cell Interactions, and Virulence of Candida albicans

(2013) Yaoping Liu et al.   EUKARYOTIC CELL

Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment

(2013) F. P. Gullo et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Functional Analysis of the Aspergillus nidulans Kinome

(2013) Colin P. De Souza et al.   PLoS One

Cryptococcus neoformans Requires the ESCRT Protein Vps23 for Iron Acquisition from Heme, for Capsule Formation, and for Virulence

(2012) Guanggan Hu et al.   INFECTION AND IMMUNITY

Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans

(2012) Hyeseung Lee et al.   MOLECULAR MICROBIOLOGY

CFGP 2.0: a versatile web-based platform for supporting comparative and evolutionary genomics of fungi and Oomycetes

(2012) Jaeyoung Choi et al.   NUCLEIC ACIDS RESEARCH

Global Analysis of Serine-Threonine Protein Kinase Genes in Neurospora crassa

(2011) Gyungsoon Park et al.   EUKARYOTIC CELL

The contribution of the S-phase checkpoint genes MEC1 and SGS1 to genome stability maintenance in Candida albicans

(2011) Melanie Legrand et al.   FUNGAL GENETICS AND BIOLOGY

InterPro in 2011: new developments in the family and domain prediction database

(2011) S. Hunter et al.   NUCLEIC ACIDS RESEARCH

Hrk1 Plays Both Hog1-Dependent and -Independent Roles in Controlling Stress Response and Antifungal Drug Resistance in Cryptococcus neoformans

(2011) Seo-Young Kim et al.   PLoS One

Inositol Pyrophosphates as Mammalian Cell Signals

(2011) A. Chakraborty et al.   Science Signaling

Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans

(2011) Seon Ah Cheon et al.   PLoS Pathogens

Functional Analysis of the Kinome of the Wheat Scab Fungus Fusarium graminearum

(2011) Chenfang Wang et al.   PLoS Pathogens

Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America

(2010) John R. Perfect et al.   CLINICAL INFECTIOUS DISEASES

The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A

(2010) Madhusudhan Srinivasan et al.   EMBO JOURNAL

Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans

(2010) Shinae Maeng et al.   EUKARYOTIC CELL

Survival Defects of Cryptococcus neoformans Mutants Exposed to Human Cerebrospinal Fluid Result in Attenuated Virulence in an Experimental Model of Meningitis

(2010) A. Lee et al.   INFECTION AND IMMUNITY

Genotype to Phenotype: A Complex Problem

(2010) R. D. Dowell et al.   SCIENCE

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers

(2009) Min Su Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance inCryptococcus neoformans

(2009) Yun C. Chang et al.   EUKARYOTIC CELL

Essential Role for Schizosaccharomyces pombe pik1 in Septation

(2009) Jae-Sook Park et al.   PLoS One

A protein kinase network regulates the function of aminophospholipid flippases

(2009) F. M. Roelants et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNUGB: a versatile genome browser supporting comparative and functional fungal genomics

(2008) Kyongyong Jung et al.   BMC GENOMICS

Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans

(2008) Oliver W. Liu et al.   CELL

PKC1Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic FungusCryptococcus neoformans

(2008) Kimberly J. Gerik et al.   EUKARYOTIC CELL

Metabolic adaptation inCryptococcus neoformansduring early murine pulmonary infection

(2008) Guanggan Hu et al.   MOLECULAR MICROBIOLOGY

SUPERFAMILY—sophisticated comparative genomics, data mining, visualization and phylogeny

(2008) Derek Wilson et al.   NUCLEIC ACIDS RESEARCH

Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases

(2008) D. M. A. Martin et al.   NUCLEIC ACIDS RESEARCH