DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective

(2015) E Andres Houseman et al.   BMC BIOINFORMATICS

Body mass index associated with genome-wide methylation in breast tissue

(2015) Brionna Y. Hair et al.   BREAST CANCER RESEARCH AND TREATMENT

A Molecular Portrait of High-Grade Ductal Carcinoma In Situ

(2015) Martin C. Abba et al.   CANCER RESEARCH

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity

(2015) Alexandra Van Keymeulen et al.   NATURE

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer

(2015) Michalina Janiszewska et al.   NATURE GENETICS

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

(2015) Colin S Cooper et al.   NATURE GENETICS

Toward understanding and exploiting tumor heterogeneity

(2015) Ash A Alizadeh et al.   NATURE MEDICINE

An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging

(2015) Tian Yuan et al.   PLoS Genetics

DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer

(2015) Kevin C. Johnson et al.   Clinical Epigenetics

Correlation of Smoking-Associated DNA Methylation Changes in Buccal Cells With DNA Methylation Changes in Epithelial Cancer

(2015) Andrew E. Teschendorff et al.   JAMA Oncology

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control

(2014) Yinming Jiao et al.   BIOINFORMATICS

Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists

(2014) Ana-Luisa Silva et al.   BMC CANCER

The Dynamics of DNA Methylation Covariation Patterns in Carcinogenesis

(2014) Andrew E. Teschendorff et al.   PLoS Computational Biology

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Charting a dynamic DNA methylation landscape of the human genome

(2013) Michael J. Ziller et al.   NATURE

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

(2013) Roderick C Slieker et al.   Epigenetics & Chromatin

An integrative network algorithm identifies age-associated differential methylation interactome hotspots targeting stem-cell differentiation pathways

(2013) James West et al.   Scientific Reports

Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development

(2013) Allison Jones et al.   PLOS MEDICINE

Epigenetic field defects in progression to cancer

(2013) Carol Bernstein   World Journal of Gastrointestinal Oncology

Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions

(2012) A. E. Teschendorff et al.   BIOINFORMATICS

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives

(2012) Kristopher L. Nazor et al.   Cell Stem Cell

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation

(2012) Andrew E Teschendorff et al.   Genome Medicine

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

Early-stage formation of an epigenetic field defect in a mouse colitis model and non-essential roles of T- and B-cells in DNA methylation induction

(2011) M Katsurano et al.   ONCOGENE

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer

(2009) Andrew E. Teschendorff et al.   PLoS One