Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity

Interaction between ROS dependent DNA damage, mitochondria and p38 MAPK underlies senescence of human adult stem cells

(2016) Aleksandra Borodkina et al.   Aging-US

Enhanced Hematopoietic Stem Cell Function Mediates Immune Regeneration following Sex Steroid Blockade

(2015) Danika M. Khong et al.   Stem Cell Reports

Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence

(2014) A. Ehninger et al.   BLOOD

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres

(2014) J. Wang et al.   BLOOD

Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression

(2014) Chia-Wei Cheng et al.   Cell Stem Cell

Thioredoxin-interacting protein, hematopoietic stem cells, and hematopoiesis

(2014) Haiyoung Jung et al.   CURRENT OPINION IN HEMATOLOGY

Purinergic P2Y14 receptor modulates stress-induced hematopoietic stem/progenitor cell senescence

(2014) Joonseok Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

(2014) Johanna Flach et al.   NATURE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

Hematopoietic stem cell niche maintenance during homeostasis and regeneration

(2014) Avital Mendelson et al.   NATURE MEDICINE

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

(2014) Jennifer D Bernet et al.   NATURE MEDICINE

Expansion of Human and Murine Hematopoietic Stem and Progenitor Cells Ex Vivo without Genetic Modification Using MYC and Bcl-2 Fusion Proteins

(2014) Gregory A. Bird et al.   PLoS One

Hematopoietic stem cells: An overview

(2014) Youssef Mohamed Mosaad   TRANSFUSION AND APHERESIS SCIENCE

TXNIP Maintains the Hematopoietic Cell Pool by Switching the Function of p53 under Oxidative Stress

(2013) Haiyoung Jung et al.   Cell Metabolism

Mechanisms that Regulate Stem Cell Aging and Life Span

(2013) Robert A.J. Signer et al.   Cell Stem Cell

Proliferation-Dependent Alterations of the DNA Methylation Landscape Underlie Hematopoietic Stem Cell Aging

(2013) Isabel Beerman et al.   Cell Stem Cell

Causes, consequences, and reversal of immune system aging

(2013) Encarnacion Montecino-Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

(2013) Maria Carolina Florian et al.   NATURE

SIRT3 Reverses Aging-Associated Degeneration

(2013) Katharine Brown et al.   Cell Reports

Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells

(2012) Jing Zou et al.   ANNALS OF HEMATOLOGY

HIF-1  deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency

(2012) J. Du et al.   BLOOD

Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation

(2012) Maria Carolina Florian et al.   Cell Stem Cell

SALL4 is a robust stimulator for the expansion of hematopoietic stem cells

(2011) J. R. Aguila et al.   BLOOD

Reactive oxygen species and hematopoietic stem cell senescence

(2011) Lijian Shao et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Inhibition of p38 Mitogen-Activated Protein Kinase Promotes Ex Vivo Hematopoietic Stem Cell Expansion

(2011) Yong Wang et al.   STEM CELLS AND DEVELOPMENT

TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells

(2010) A. D. Domashenko et al.   BLOOD

p38MAPK Controls Expression of Multiple Cell Cycle Inhibitors and Islet Proliferation with Advancing Age

(2009) Esther Sook Miin Wong et al.   DEVELOPMENTAL CELL

Selectivity of Docking Sites in MAPK Kinases

(2009) A. Jane Bardwell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-Interacting Protein Regulates Hematopoietic Stem Cell Quiescence and Mobilization under Stress Conditions

(2009) M. Jeong et al.   JOURNAL OF IMMUNOLOGY

MAPK signaling pathways in the regulation of hematopoiesis

(2009) Christian R. Geest et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of Inflammation by a p38 MAP Kinase Targeted Cell Permeable Peptide

(2008) Jing Fu et al.   Medicinal Chemistry