ELL targets c-Myc for proteasomal degradation and suppresses tumour growth

Metastasis-associated S100A4 is a specific amine donor and an activity-independent binding partner of transglutaminase-2

(2015) B. Biri et al.   BIOCHEMICAL JOURNAL

Molecular targets and pathways involved in liver metastasis of colorectal cancer

(2015) Ulrich H. Weidle et al.   CLINICAL & EXPERIMENTAL METASTASIS

S100A4 and its role in metastasis – computational integration of data on biological networks

(2015) Antoine Buetti-Dinh et al.   Molecular BioSystems

CCAAT/enhancer binding protein β induces motility and invasion of glioblastoma cells through transcriptional regulation of the calcium binding protein S100A4

(2015) Diana Aguilar-Morante et al.   Oncotarget

Systemic shRNA mediated knock-down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation

(2015) Mathias Dahlmann et al.   Oncotarget

Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer

(2015) Lydia Kriegl et al.   Oncotarget

Anti-S100A4 Antibody Suppresses Metastasis Formation by Blocking Stroma Cell Invasion

(2015) Jörg Klingelhöfer et al.   NEOPLASIA

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

(2014) Susann Weissmueller et al.   CELL

The Von Hippel-Lindau Protein Suppresses Androgen Receptor Activity

(2014) Jing Wang et al.   MOLECULAR ENDOCRINOLOGY

New insights into ubiquitin E3 ligase mechanism

(2014) Christopher E Berndsen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis and are targets of metastasis-inducing S100A4

(2014) M T Hansen et al.   ONCOGENE

p53/p63/p73 in the Epidermis in Health and Disease

(2014) V. A. Botchkarev et al.   Cold Spring Harbor Perspectives in Medicine

MYC and Transcription Elongation

(2014) P. B. Rahl et al.   Cold Spring Harbor Perspectives in Medicine

Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth

(2013) Takahiro Ochiya et al.   ANGIOGENESIS

Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression

(2013) Linsey Reavie et al.   CANCER CELL

Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence

(2013) Shoichiro Takeishi et al.   CANCER CELL

The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability

(2013) Bryan King et al.   CELL

Transcriptional elongation checkpoint control in development and disease

(2013) E. Smith et al.   GENES & DEVELOPMENT

ELL Inhibits E2F1 Transcriptional Activity by Enhancing E2F1 Deacetylation via Recruitment of Histone Deacetylase 1

(2013) W. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

The Little Elongation Complex Functions at Initiation and Elongation Phases of snRNA Gene Transcription

(2013) Deqing Hu et al.   MOLECULAR CELL

ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair

(2013) S. Mourgues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer

(2012) Kristin Jonsdottir et al.   BREAST CANCER RESEARCH AND TREATMENT

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

MicroRNA-26a Is Strongly Downregulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains (SODD)

(2012) Steven N. Reuland et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Super Elongation Complex Family of RNA Polymerase II Elongation Factors: Gene Target Specificity and Transcriptional Output

(2012) Z. Luo et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ubiquitin Ligase Siah1 Controls ELL2 Stability and Formation of Super Elongation Complexes to Modulate Gene Transcription

(2012) Min Liu et al.   MOLECULAR CELL

The VHL/HIF axis in clear cell renal carcinoma

(2012) Chuan Shen et al.   SEMINARS IN CANCER BIOLOGY

The Pathogenesis of Mixed-Lineage Leukemia

(2011) Andrew G. Muntean et al.   Annual Review of Pathology-Mechanisms of Disease

S100A4 calcium-binding protein is key player in tumor progression and metastasis: preclinical and clinical evidence

(2011) Shrawan Kumar Mishra et al.   CANCER AND METASTASIS REVIEWS

Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC)

(2011) C. Lin et al.   GENES & DEVELOPMENT

RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression

(2011) Efrat Shema et al.   MOLECULAR CELL

The Little Elongation Complex Regulates Small Nuclear RNA Transcription

(2011) Edwin R. Smith et al.   MOLECULAR CELL

Transcription Factor IIS Cooperates with the E3 Ligase UBR5 to Ubiquitinate the CDK9 Subunit of the Positive Transcription Elongation Factor B

(2010) Marilena Cojocaru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription

(2010) Nanhai He et al.   MOLECULAR CELL

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

(2010) Chengqi Lin et al.   MOLECULAR CELL

HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP

(2010) Bijan Sobhian et al.   MOLECULAR CELL

Ubiquitylation of the amino terminus of Myc by SCFβ-TrCP antagonizes SCFFbw7-mediated turnover

(2010) Nikita Popov et al.   NATURE CELL BIOLOGY

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity

(2010) Lukas Flatz et al.   NATURE MEDICINE

Critical Role of ESCRT Machinery in EGFR Recycling

(2009) Aleksander Baldys et al.   BIOCHEMISTRY

Nucleophosmin/B23 Regulates Ubiquitin Dynamics in Nucleoli by Recruiting Deubiquitylating Enzyme USP36

(2009) Akinori Endo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A c-Myc–SIRT1 feedback loop regulates cell growth and transformation

(2009) Jian Yuan et al.   JOURNAL OF CELL BIOLOGY

Cholestane Glycosides and Trihydroxy Fatty Acids from the Rhizomes ofDioscorea septemloba

(2009) Xue-Ting Liu et al.   PLANTA MEDICA

E2F – at the crossroads of life and death

(2008) Shirley Polager et al.   TRENDS IN CELL BIOLOGY