Predicting quantitative traits from genome and phenome with near perfect accuracy

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

(2015) Jian Yang et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

A random forest approach to capture genetic effects in the presence of population structure

(2015) Johannes Stephan et al.   Nature Communications

Genetic interactions contribute less than additive effects to quantitative trait variation in yeast

(2015) Joshua S. Bloom et al.   Nature Communications

Predictability Bounds of Electronic Health Records

(2015) Dominik Dahlem et al.   Scientific Reports

Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions

(2015) Matthew B. Taylor et al.   PLoS Genetics

Estimation of Epistatic Variance Components and Heritability in Founder Populations and Crosses

(2014) Alexander I. Young et al.   GENETICS

Heritability and genetic basis of protein level variation in an outbred population

(2014) Leopold Parts et al.   GENOME RESEARCH

Genetics of single-cell protein abundance variation in large yeast populations

(2014) Frank W. Albert et al.   NATURE

High-Resolution Mapping of Complex Traits with a Four-Parent Advanced Intercross Yeast Population

(2013) Francisco A. Cubillos et al.   GENETICS

Finding the sources of missing heritability in a yeast cross

(2013) Joshua S. Bloom et al.   NATURE

Inferring Genome-Wide Recombination Landscapes from Advanced Intercross Lines: Application to Yeast Crosses

(2013) Christopher J. R. Illingworth et al.   PLoS One

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Improved Heritability Estimation from Genome-wide SNPs

(2012) Doug Speed et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Whole-Genome Regression and Prediction Methods Applied to Plant and Animal Breeding

(2012) G. de los Campos et al.   GENETICS

Genomic Prediction in Animals and Plants: Simulation of Data, Validation, Reporting, and Benchmarking

(2012) H. D. Daetwyler et al.   GENETICS

Comparison of Family History and SNPs for Predicting Risk of Complex Disease

(2012) Chuong B. Do et al.   PLoS Genetics

Risk Prediction of Complex Diseases from Family History and Known Susceptibility Loci, with Applications for Cancer Screening

(2011) Hon-Cheong So et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mining for genotype-phenotype relations in Saccharomyces using partial least squares

(2011) Tahir Mehmood et al.   BMC BIOINFORMATICS

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

(2011) Hon-Cheong So et al.   GENETIC EPIDEMIOLOGY

Revealing the genetic structure of a trait by sequencing a population under selection

(2011) L. Parts et al.   GENOME RESEARCH

Predicting phenotypic variation in yeast from individual genome sequences

(2011) Rob Jelier et al.   NATURE GENETICS

Beyond Missing Heritability: Prediction of Complex Traits

(2011) Robert Makowsky et al.   PLoS Genetics

Dissection of genetically complex traits with extremely large pools of yeast segregants

(2010) Ian M. Ehrenreich et al.   NATURE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Predicting human height by Victorian and genomic methods

(2009) Yurii S Aulchenko et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Genetic Risk Prediction — Are We There Yet?

(2009) Peter Kraft et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Interactions Between Transcription Factors Cause Natural Variation in Yeast

(2009) J. Gerke et al.   SCIENCE

Epistasis in a quantitative trait captured by a molecular model of transcription factor interactions

(2009) Jason Gertz et al.   THEORETICAL POPULATION BIOLOGY