Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage

Quantification of Quaternary Structure Stability in Aggregation-Prone Proteins under Physiological Conditions: The Transthyretin Case

(2014) Lei Z. Robinson et al.   BIOCHEMISTRY

Age-Related Oxidative Modifications of Transthyretin Modulate Its Amyloidogenicity

(2013) Lei Zhao et al.   BIOCHEMISTRY

AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin

(2013) S. C. Penchala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why are some amyloidoses systemic? Does hepatic “chaperoning at a distance” prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?

(2012) Joel N. Buxbaum et al.   FASEB JOURNAL

Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

(2011) Steve Bourgault et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity

(2011) M. M. Alhamadsheh et al.   Science Translational Medicine

Common Membrane Trafficking Defects of Disease-Associated Dynamin 2 Mutations

(2011) Ya-Wen Liu et al.   TRAFFIC

Lipid rafts: Keys to neurodegeneration

(2010) Cara-Lynne Schengrund   BRAIN RESEARCH BULLETIN

A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity

(2010) Sungwook Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma

(2010) Sungwook Choi et al.   Nature Chemical Biology

Transthyretin: the servant of many masters

(2009) Joel N. Buxbaum et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prefibrillar transthyretin oligomers and cold stored native tetrameric transthyretin are cytotoxic in cell culture

(2008) Karin Sörgjerd et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes

(2007) Xu Hou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES