Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions

Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli

(2015) James C. Cronk et al.   IMMUNITY

Dysregulated brain immunity and neurotrophin signaling in Rett syndrome and autism spectrum disorders

(2015) Theoharis C. Theoharides et al.   JOURNAL OF NEUROIMMUNOLOGY

Function and information content of DNA methylation

(2015) Dirk Schübeler   NATURE

Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages

(2015) MacLean Sellars et al.   NATURE IMMUNOLOGY

The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

(2015) Erin Knock et al.   Neural Development

Autism Spectrum Disorders: Translating human deficits into mouse behavior

(2015) E. Pasciuto et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms

(2015) Valentina Conti et al.   PLoS One

The nucleosome remodeling and deacetylase complex in development and disease

(2015) Jeannine Basta et al.   Translational Research

Methyl-CpG-binding domain proteins: readers of the epigenome

(2015) Qian Du et al.   Epigenomics

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

(2015) Peter C. Cook et al.   Nature Communications

Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

(2014) Yu Lu et al.   Cell Stem Cell

Genomic patterns and context specific interpretation of DNA methylation

(2014) Tuncay Baubec et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Disruption of Mbd5 in mice causes neuronal functional deficits and neurobehavioral abnormalities consistent with 2q23.1 microdeletion syndrome

(2014) V. Camarena et al.   EMBO Molecular Medicine

DNA methylation is required for the control of stem cell differentiation in the small intestine

(2014) K. L. Sheaffer et al.   GENES & DEVELOPMENT

MBD2 regulates TH17 differentiation and experimental autoimmune encephalomyelitis by controlling the homeostasis of T-bet/Hlx axis

(2014) Jixin Zhong et al.   JOURNAL OF AUTOIMMUNITY

Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation

(2014) G. Lal et al.   JOURNAL OF IMMUNOLOGY

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

(2014) Michael Waterfield et al.   NATURE IMMUNOLOGY

Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain

(2014) Tomoko Yamada et al.   NEURON

Transcriptional co-repressors and memory storage

(2014) Hannah Schoch et al.   NEUROPHARMACOLOGY

Methylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family

(2013) Tuncay Baubec et al.   CELL

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Transcriptional repressors: multifaceted regulators of gene expression

(2013) N. Reynolds et al.   DEVELOPMENT

Restoration of Dopamine Signaling to the Dorsal Striatum Is Sufficient for Aspects of Active Maternal Behavior in Female Mice

(2013) Charles W. Henschen et al.   ENDOCRINOLOGY

Mbd2 Promotes Foxp3 Demethylation and T-Regulatory-Cell Function

(2013) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

(2013) Junjie U Guo et al.   NATURE NEUROSCIENCE

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

(2013) Matthew J Lyst et al.   NATURE NEUROSCIENCE

DNA methylation: roles in mammalian development

(2013) Zachary D. Smith et al.   NATURE REVIEWS GENETICS

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences

(2013) Katharina Günther et al.   NUCLEIC ACIDS RESEARCH

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

The Expanding Role of MBD Genes in Autism: Identification of aMECP2Duplication and Novel Alterations inMBD5,MBD6, andSETDB1

(2012) Holly N. Cukier et al.   Autism Research

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

(2012) Rodney C Samaco et al.   NATURE GENETICS

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

(2012) Hideharu Hashimoto et al.   NUCLEIC ACIDS RESEARCH

Assessment of 2q23.1 Microdeletion Syndrome Implicates MBD5 as a Single Causal Locus of Intellectual Disability, Epilepsy, and Autism Spectrum Disorder

(2011) Michael E. Talkowski et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Deconstructing Sociability, An Autism-Relevant Phenotype, in Mouse Models

(2011) Andrew H. Fairless et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Biogenic amines and their metabolites are differentially affected in the Mecp2-deficient mouse brain

(2011) Nicolas Panayotis et al.   BMC NEUROSCIENCE

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

(2011) S. C. McQuown et al.   JOURNAL OF NEUROSCIENCE

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses

(2011) Darren Goffin et al.   NATURE NEUROSCIENCE

CHD5, a Brain-Specific Paralog of Mi2 Chromatin Remodeling Enzymes, Regulates Expression of Neuronal Genes

(2011) Rebecca Casaday Potts et al.   PLoS One

Epigenetic Regulation of miR-184 by MBD1 Governs Neural Stem Cell Proliferation and Differentiation

(2010) Changmei Liu et al.   Cell Stem Cell

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

Novel variants identified in methyl-CpG-binding domain genes in autistic individuals

(2009) Holly N. Cukier et al.   NEUROGENETICS

The Methyl-CpG Binding Proteins Mecp2, Mbd2 and Kaiso Are Dispensable for Mouse Embryogenesis, but Play a Redundant Function in Neural Differentiation

(2009) Isabel Martín Caballero et al.   PLoS One

Dopamine Signaling in the Dorsal Striatum Is Essential for Motivated Behaviors

(2008) Richard D. Palmiter   Annals of the New York Academy of Sciences

Reduced body weight is a common effect of gene knockout in mice

(2008) Danielle R Reed et al.   BMC GENETICS

The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits

(2008) A. M. Allan et al.   HUMAN MOLECULAR GENETICS

Deficiency of Mbd2 Attenuates Wnt Signaling

(2008) T. J. Phesse et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA methylation landscapes: provocative insights from epigenomics

(2008) Miho M. Suzuki et al.   NATURE REVIEWS GENETICS

MBD2-Mediated Transcriptional Repression of the p14ARF Tumor Suppressor Gene in Human Colon Cancer Cells

(2008) Valérie Martin et al.   PATHOBIOLOGY

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE