Tick tock: DNA methylation, the epigenetic clock and exceptional longevity

Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels

(2016) Steve Horvath et al.   Aging-US

HDAC inhibition in thecpfl1mouse protects degenerating cone photoreceptorsin vivo

(2016) Dragana Trifunović et al.   HUMAN MOLECULAR GENETICS

Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

(2016) Andrew M. Gross et al.   MOLECULAR CELL

The Framingham Heart Study — 67 years of discovery in metabolic disease

(2016) Michelle T. Long et al.   Nature Reviews Endocrinology

Epigenome Editing: State of the Art, Concepts, and Perspectives

(2016) Goran Kungulovski et al.   TRENDS IN GENETICS

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

(2015) Steve Horvath et al.   Aging-US

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

(2015) Riccardo E Marioni et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

(2015) Isaac B Hilton et al.   NATURE BIOTECHNOLOGY

Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging

(2015) Marc Jung et al.   NUCLEIC ACIDS RESEARCH

DNA methylation profiling: comparison of genome-wide sequencing methods and the Infinium Human Methylation 450 Bead Chip

(2015) Denise L Walker et al.   Epigenomics

Genetic factors and epigenetic mechanisms of longevity: current perspectives

(2015) Jessica Lazarus et al.   Epigenomics

DNA methylation age of blood predicts all-cause mortality in later life

(2015) Riccardo E Marioni et al.   GENOME BIOLOGY

DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain

(2014) Alicia K. Smith et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

(2014) Joris Deelen et al.   HUMAN MOLECULAR GENETICS

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

(2014) Carola Weidner et al.   GENOME BIOLOGY

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites

(2013) I. Florath et al.   HUMAN MOLECULAR GENETICS

The Sydney Centenarian Study: methodology and profile of centenarians and near-centenarians

(2013) Perminder S. Sachdev et al.   INTERNATIONAL PSYCHOGERIATRICS

DNA Isolation Method Is a Source of Global DNA Methylation Variability Measured with LUMA. Experimental Analysis and a Systematic Review

(2013) Carolina Soriano-Tárraga et al.   PLoS One

Storage conditions and stability of global DNA methylation in placental tissue

(2013) Nadia Vilahur et al.   Epigenomics

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Epigenetic Predictor of Age

(2011) Sven Bocklandt et al.   PLoS One