Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation

Autophagy in the lens

(2016) Hideaki Morishita et al.   EXPERIMENTAL EYE RESEARCH

Unfolded-protein response–associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract

(2016) Lei Lyu et al.   FASEB JOURNAL

Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells

(2014) Subhasree Basu et al.   Autophagy

Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly

(2014) B. R. Chaffee et al.   DEVELOPMENT

The cellular and molecular mechanisms of vertebrate lens development

(2014) A. Cvekl et al.   DEVELOPMENT

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation

(2014) Matías Alvarez-Saavedra et al.   Nature Communications

HSF4 regulates DLAD expression and promotes lens de-nucleation

(2013) Xiukun Cui et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

(2013) Jovica Ninkovic et al.   Cell Stem Cell

Autophagy and mitophagy participate in ocular lens organelle degradation

(2013) M. Joseph Costello et al.   EXPERIMENTAL EYE RESEARCH

SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling

(2013) Debra Toiber et al.   MOLECULAR CELL

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300

(2013) Louise Wolf et al.   NUCLEIC ACIDS RESEARCH

Chromatin-Remodeling Factor Brg1 Is Required for Schwann Cell Differentiation and Myelination

(2012) Matthias Weider et al.   DEVELOPMENTAL CELL

Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development

(2012) Tien T. Le et al.   DEVELOPMENTAL DYNAMICS

Pax6: A multi-level regulator of ocular development

(2012) Ohad Shaham et al.   PROGRESS IN RETINAL AND EYE RESEARCH

ATP-dependent chromatin remodeling in the DNA-damage response

(2012) Hannes Lans et al.   Epigenetics & Chromatin

The chromatin remodeling factor BRG1 stimulates nucleotide excision repair by facilitating recruitment of XPC to sites of DNA damage

(2011) Ling Zhang et al.   CELL CYCLE

Conditional ablation of the Notch2 receptor in the ocular lens

(2011) Senthil S. Saravanamuthu et al.   DEVELOPMENTAL BIOLOGY

The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens

(2011) L. A. Wiley et al.   Disease Models & Mechanisms

esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function

(2011) Lena Ho et al.   NATURE CELL BIOLOGY

Biological glass: structural determinants of eye lens transparency

(2011) S. Bassnett et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The lens: a classical model of embryonic induction providing new insights into cell determination in early development

(2011) L. Gunhaga   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism

(2011) Fabian Erdel et al.   Nucleus

Cell proliferation in the absence of E2F1-3

(2010) Pamela L. Wenzel et al.   DEVELOPMENTAL BIOLOGY

A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair

(2010) Han-Sae Lee et al.   EMBO JOURNAL

The Nucleosome Remodeling Factor ISWI Functionally Interacts With an Evolutionarily Conserved Network of Cellular Factors

(2010) W. Arancio et al.   GENETICS

The lens epithelium in ocular health and disease

(2010) G. Martinez et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lens Fiber Cell Differentiation and Denucleation Are Disrupted through Expression of the N-Terminal Nuclear Receptor Box of Ncoa6 and Result in p53-dependent and p53-independent Apoptosis

(2010) Wei-Lin Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE

Perturbing the Ubiquitin Pathway Reveals How Mitosis Is Hijacked to Denucleate and Regulate Cell Proliferation and Differentiation In Vivo

(2010) Andrea Caceres et al.   PLoS One

Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription

(2010) Liling Tang et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

(2010) Shuying He et al.   Epigenetics & Chromatin

Cell death in the skin

(2009) Saskia Lippens et al.   APOPTOSIS

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Pax6 is essential for lens fiber cell differentiation

(2009) O. Shaham et al.   DEVELOPMENT

Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival

(2009) Giuseppe F. Pontoriero et al.   DEVELOPMENTAL BIOLOGY

Pitx3 controls multiple aspects of lens development

(2009) Olga Medina-Martinez et al.   DEVELOPMENTAL DYNAMICS

Transcription factor GATA-3 is essential for lens development

(2009) Atsuko Maeda et al.   DEVELOPMENTAL DYNAMICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens

(2009) Louise V. Wolf et al.   PLoS One

Notch signaling regulates growth and differentiation in the mammalian lens

(2008) Sheldon Rowan et al.   DEVELOPMENTAL BIOLOGY

Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

(2008) Haotian Zhao et al.   DEVELOPMENTAL BIOLOGY

On the mechanism of organelle degradation in the vertebrate lens

(2008) Steven Bassnett   EXPERIMENTAL EYE RESEARCH

Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells

(2008) Hsin-Yi Ho et al.   MECHANISMS OF DEVELOPMENT

SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells

(2008) Benjamin L. Kidder et al.   STEM CELLS

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development

(2007) C. T. Griffin et al.   DEVELOPMENT