IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle Cells

Sarcopenia, obesity, and natural killer cell immune senescence in aging: Altered cytokine levels as a common mechanism

(2016) Charles T. Lutz et al.   Aging-US

Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging

(2015) Justin D. Crane et al.   AGING CELL

IL-15 concentrations in skeletal muscle and subcutaneous adipose tissue in lean and obese humans: local effects of IL-15 on adipose tissue lipolysis

(2015) Joseph R. Pierce et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha

(2015) Grant C. O'Connell et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of skeletal muscle mitochondrial function by nuclear receptors: implications for health and disease

(2015) Joaquin Perez-Schindler et al.   CLINICAL SCIENCE

PPARs and ERRs: molecular mediators of mitochondrial metabolism

(2015) Weiwei Fan et al.   CURRENT OPINION IN CELL BIOLOGY

Myokines in insulin resistance and type 2 diabetes

(2014) Kristin Eckardt et al.   DIABETOLOGIA

Hydrodynamic delivery of interleukin 15 gene promotes resistance to high fat diet-induced obesity, fatty liver and improves glucose homeostasis

(2014) H Sun et al.   GENE THERAPY

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

AMPK-α2 is involved in exercise training-induced adaptations in insulin-stimulated metabolism in skeletal muscle following high-fat diet

(2014) Marcia J. Abbott et al.   JOURNAL OF APPLIED PHYSIOLOGY

Identification of human exercise-induced myokines using secretome analysis

(2014) Milène Catoire et al.   PHYSIOLOGICAL GENOMICS

Interleukin-15 and Soluble Interleukin-15 Receptor α in Coronary Artery Disease Patients: Association with Epicardial Fat and Indices of Adipose Tissue Distribution

(2014) Elena Dozio et al.   PLoS One

Interleukin-15 Modulates Adipose Tissue by Altering Mitochondrial Mass and Activity

(2014) Nicole G. Barra et al.   PLoS One

Mitochondrial Involvement and Impact in Aging Skeletal Muscle

(2014) Russell T. Hepple   Frontiers in Aging Neuroscience

Desnutrin/ATGL Activates PPARδ to Promote Mitochondrial Function for Insulin Secretion in Islet β Cells

(2013) Tianyi Tang et al.   Cell Metabolism

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

(2013) Brendan Egan et al.   Cell Metabolism

Increased Bone Mass in Mice Lacking the Adipokine Apelin

(2013) Lalita Wattanachanya et al.   ENDOCRINOLOGY

IL-15 Is Required for Postexercise Induction of the Pro-Oxidative Mediators PPARδ and SIRT1 in Male Mice

(2013) LeBris S. Quinn et al.   ENDOCRINOLOGY

Adipo-Myokines: Two Sides of the Same Coin—Mediators of Inflammation and Mediators of Exercise

(2013) Silja Raschke et al.   MEDIATORS OF INFLAMMATION

Regulating the immune system via IL-15 transpresentation

(2012) Eliseo F. Castillo et al.   CYTOKINE

IL-15 Overexpression Promotes Endurance, Oxidative Energy Metabolism, and Muscle PPARδ, SIRT1, PGC-1α, and PGC-1β Expression in Male Mice

(2012) LeBris S. Quinn et al.   ENDOCRINOLOGY

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

PPARs: Fatty acid sensors controlling metabolism

(2012) Lars la Cour Poulsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The effect of exercise induced cytokines on insulin stimulated glucose transport in C2C12 cells

(2011) Stuart Robert Gray et al.   CYTOKINE

AMPKα2 deficiency uncovers time dependency in the regulation of contraction-induced palmitate and glucose uptake in mouse muscle

(2011) Marcia J. Abbott et al.   JOURNAL OF APPLIED PHYSIOLOGY

PGC-1α and Myokines in the Aging Muscle – A Mini-Review

(2010) Anne-Sophie Arnold et al.   GERONTOLOGY

CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle

(2009) Marcia J. Abbott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) acts as regulator of metabolism linked to multiple cellular functions

(2009) Kay-Dietrich Wagner et al.   PHARMACOLOGY & THERAPEUTICS

Oversecretion of interleukin-15 from skeletal muscle reduces adiposity

(2008) LeBris S. Quinn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipokines, Myokines and Cardiovascular Disease

(2008) Kenneth Walsh   CIRCULATION JOURNAL

Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity

(2008) Josep M. Argilés et al.   DRUG DISCOVERY TODAY

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

Effects of IL-15 on Rat Brown Adipose Tissue: Uncoupling Proteins and PPARs

(2008) Vanessa Almendro et al.   Obesity