Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin

(2016) Michael C. Velarde et al.   Aging-US

Effects of Creatine and Exercise on Skeletal Muscle of FRG1-Transgenic Mice

(2014) Daniel I. Ogborn et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

Comparative study of various growth factors and cytokines on type I collagen and hyaluronan production in human dermal fibroblasts

(2014) Mi-Sun Kim et al.   Journal of Cosmetic Dermatology

Elevated Mitochondrial Oxidative Stress Impairs Metabolic Adaptations to Exercise in Skeletal Muscle

(2013) Justin D. Crane et al.   PLoS One

Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15R 

(2013) J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

(2012) Jorge L. Ruas et al.   CELL

Long-term Aerobic Exercise Is Associated With Greater Muscle Strength Throughout the Life Span

(2012) J. D. Crane et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

(2012) Hayley M. O’Neill et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse

(2012) Lloye M. Dillon et al.   PLoS One

Hormonal Therapy of Intrinsic Aging

(2012) C.C. Zouboulis et al.   REJUVENATION RESEARCH

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

(2011) T. A. Waldmann et al.   BLOOD

Upregulation of circulating IL-15 by treadmill running in healthy individuals: Is IL-15 an endocrine mediator of the beneficial effects of endurance exercise?

(2011) Yoshiaki Tamura et al.   ENDOCRINE JOURNAL

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

(2011) A. Safdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue

(2010) Nicolai Treiber et al.   AGING CELL

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

PPARδ promotes wound healing by up-regulating TGF-β1-dependent or -independent expression of extracellular matrix proteins

(2009) Sun Ah Ham et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Habitual exercise and vascular ageing

(2009) Douglas R. Seals et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oversecretion of interleukin-15 from skeletal muscle reduces adiposity

(2008) LeBris S. Quinn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reduced Disability and Mortality Among Aging Runners

(2008) Eliza F. Chakravarty   ARCHIVES OF INTERNAL MEDICINE

Endurance Exercise as a Countermeasure for Aging

(2008) I. R. Lanza et al.   DIABETES

Partial Depletion of Mitochondrial DNA from Human Skin Fibroblasts Induces a Gene Expression Profile Reminiscent of Photoaged Skin

(2008) Peter Schroeder et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY