EMC6/TMEM93 suppresses glioblastoma proliferation by modulating autophagy

AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferation

(2015) Valentina Cianfanelli et al.   CELL CYCLE

Autophagy in stress and disease

(2015) M Chiara Maiuri et al.   CELL DEATH AND DIFFERENTIATION

Cytoplasmic Accumulation of Sequestosome 1 (p62) Is a Predictor of Biochemical Recurrence, Rapid Tumor Cell Proliferation, and Genomic Instability in Prostate Cancer

(2015) C. Burdelski et al.   CLINICAL CANCER RESEARCH

Quantum Dots-Based Quantitative and In Situ Multiple Imaging on Ki67 and Cytokeratin to Improve Ki67 Assessment in Breast Cancer

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Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide

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CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

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A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy

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Resveratrol abrogates the Temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the Temozolomide-induced senescence in glioma cells

(2013) Eduardo C Filippi-Chiela et al.   BMC CANCER

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

(2013) Yongjie Wei et al.   CELL

Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer

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A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy

(2012) Yanjun Li et al.   Autophagy

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Autophagy and Cancer

(2012) Francesca Aredia et al.   Cells

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention

(2011) Niroop Kaza et al.   BRAIN PATHOLOGY

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

(2011) W Gao et al.   CELL DEATH AND DIFFERENTIATION

Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin

(2011) Hui-Wen Chiu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Regulation of DNA Repair Mechanism in Human Glioma Xenograft Cells both In Vitro and In Vivo in Nude Mice

(2011) Shivani Ponnala et al.   PLoS One

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

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Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

(2010) Andrew C. Hsieh et al.   CANCER CELL

Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis

(2010) Ting-Kuang Niu et al.   FEBS LETTERS

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L

(2010) Kohichi Matsunaga et al.   JOURNAL OF CELL BIOLOGY

Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors

(2010) Xin Huang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

(2010) R. J. O. Dowling et al.   SCIENCE

The role of autophagy in sensitizing malignant glioma cells to radiation therapy

(2009) W. Zhuang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Anti- and pro-tumor functions of autophagy

(2009) Eugenia Morselli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy and the functional roles of Atg5 and beclin-1 in the anti-tumor effects of 3β androstene 17α diol neuro-steroid on malignant glioma cells

(2009) Martin R. Graf et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY