Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis

Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient MiceSignificance

(2016) Amanda C. Foks et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The GTP-bound and Sumoylated Form of the rab17 Small Molecular Weight GTPase Selectively Binds Syntaxin 2 in Polarized Hepatic WIF-B Cells

(2016) Anneliese C. Striz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells

(2016) Amra Saric et al.   MOLECULAR BIOLOGY OF THE CELL

Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15:01 Status

(2016) Michele D. Binder et al.   PLoS Genetics

Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis

(2015) Nicolas J. Pillon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis

(2015) Susan M. Armstrong et al.   CARDIOVASCULAR RESEARCH

The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses

(2015) Christina E. Arnold et al.   IMMUNOBIOLOGY

Pathogenic immunity in systemic lupus erythematosus and atherosclerosis: common mechanisms and possible targets for intervention

(2015) M. Wigren et al.   JOURNAL OF INTERNAL MEDICINE

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis

(2015) Huan Tao et al.   JOURNAL OF LIPID RESEARCH

Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells

(2015) Paymon M. Azizi et al.   MOLECULAR BIOLOGY OF THE CELL

PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines

(2015) Y-S Yoon et al.   Mucosal Immunology

Ubiquitination by March-I prevents MHC class II recycling and promotes MHC class II turnover in antigen-presenting cells

(2015) Kyung-Jin Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group AStreptococcusinvasion

(2014) Bijaya Haobam et al.   CELLULAR MICROBIOLOGY

ERK5 Activation in Macrophages Promotes Efferocytosis and Inhibits Atherosclerosis

(2014) Kyung-Sun Heo et al.   CIRCULATION

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

(2014) Jamie C. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Engulfment of Apoptotic Cells by Macrophages: A Role of MicroRNA-21 in the Resolution of Wound Inflammation

(2014) A. Das et al.   JOURNAL OF IMMUNOLOGY

Transcriptomic Profiling of the Development of the Inflammatory Response in Human Monocytes In Vitro

(2014) Paola Italiani et al.   PLoS One

Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart

(2014) Kory J. Lavine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity

(2014) Stanley Gititu Kimani et al.   Frontiers in Immunology

5-Lipoxygenase contributes to PPARγ activation in macrophages in response to apoptotic cells

(2013) Andreas von Knethen et al.   CELLULAR SIGNALLING

Rabex-5 Protein Regulates Dendritic Localization of Small GTPase Rab17 and Neurite Morphogenesis in Hippocampal Neurons

(2013) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proresolving and Tissue-Protective Actions of Annexin A1-Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor

(2013) J. Dalli et al.   JOURNAL OF IMMUNOLOGY

Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity

(2013) Pedro Recarte-Pelz et al.   ARTHRITIS RESEARCH & THERAPY

Apoptotic Cell Death and Efferocytosis in Atherosclerosis

(2012) Emily A. Van Vré et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The atypical chemokine receptor D6 controls macrophage efferocytosis and cytokine secretion during the resolution of inflammation

(2012) Ester Pashover-Schallinger et al.   FASEB JOURNAL

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane

(2012) Hao Wang et al.   MOLECULAR BIOLOGY OF THE CELL

The Cell Biology of Phagocytosis

(2011) Ronald S. Flannagan et al.   Annual Review of Pathology-Mechanisms of Disease

Membrane dynamics and fusion at late endosomes and vacuoles – Rab regulation, multisubunit tethering complexes and SNAREs

(2011) Nadine Epp et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis

(2011) Edward Thorp et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NADPH Oxidase Is Internalized by Clathrin-coated Pits and Localizes to a Rab27A/B GTPase-regulated Secretory Compartment in Activated Macrophages

(2011) Patrick Ejlerskov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-3 is a new MerTK-specific eat-me signal

(2011) Nora B. Caberoy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IgG Autoantibodies against Deposited C3 Inhibit Macrophage-Mediated Apoptotic Cell Engulfment in Systemic Autoimmunity

(2011) K. D. Kenyon et al.   JOURNAL OF IMMUNOLOGY

PTEN Negatively Regulates Engulfment of Apoptotic Cells by Modulating Activation of Rac GTPase

(2011) S. Mondal et al.   JOURNAL OF IMMUNOLOGY

ReCLIP (Reversible Cross-Link Immuno-Precipitation): An Efficient Method for Interrogation of Labile Protein Complexes

(2011) Andrew L. Smith et al.   PLoS One

The Recycling Endosome Protein Rab17 Regulates Melanocytic Filopodia Formation and Melanosome Trafficking

(2011) Kimberley A. Beaumont et al.   TRAFFIC

Modulation of Macrophage Efferocytosis in Inflammation

(2011) Darlynn Korns et al.   Frontiers in Immunology

Mechanisms of failed apoptotic cell clearance by phagocyte subsets in cardiovascular disease

(2010) Edward B. Thorp   APOPTOSIS

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

Membrane phospholipid metabolism during phagocytosis in human neutrophils

(2010) Reiko Minakami et al.   GENES TO CELLS

Prolonged Antigen Storage Endows Merocytic Dendritic Cells with Enhanced Capacity To Prime Anti-Tumor Responses in Tumor-Bearing Mice

(2010) R. A. Reboulet et al.   JOURNAL OF IMMUNOLOGY

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

Ubiquitination regulates MHC class II-peptide complex retention and degradation in dendritic cells

(2010) E. Walseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retromer Is Required for Apoptotic Cell Clearance by Phagocytic Receptor Recycling

(2010) D. Chen et al.   SCIENCE

Mechanisms and consequences of efferocytosis in advanced atherosclerosis

(2009) Edward Thorp et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mertk Receptor Mutation Reduces Efferocytosis Efficiency and Promotes Apoptotic Cell Accumulation and Plaque Necrosis in Atherosclerotic Lesions of Apoe −/− Mice

(2008) Edward Thorp et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

(2008) Takaharu Ichimura et al.   JOURNAL OF CLINICAL INVESTIGATION

Imaging of Rab5 activity identifies essential regulators for phagosome maturation

(2008) Masahiro Kitano et al.   NATURE

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY