Genetic Deletion of TREK-1 or TWIK-1/TREK-1 Potassium Channels does not Alter the Basic Electrophysiological Properties of Mature Hippocampal Astrocytes In Situ

Freshly dissociated mature hippocampal astrocytes exhibit passive membrane conductance and low membrane resistance similarly to syncytial coupled astrocytes

(2015) Yixing Du et al.   JOURNAL OF NEUROPHYSIOLOGY

New Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia Signaling

(2015) M. L. Olsen et al.   JOURNAL OF NEUROSCIENCE

mGluR3 Activation Recruits Cytoplasmic TWIK-1 Channels to Membrane that Enhances Ammonium Uptake in Hippocampal Astrocytes

(2015) Wei Wang et al.   MOLECULAR NEUROBIOLOGY

βIV-Spectrin regulates TREK-1 membrane targeting in the heart

(2014) Thomas J. Hund et al.   CARDIOVASCULAR RESEARCH

DNA methylation functions as a critical regulator of Kir4.1 expression during CNS development

(2014) Sinifunanya E. Nwaobi et al.   GLIA

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

(2014) Xiaoping Tong et al.   NATURE NEUROSCIENCE

A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes

(2014) Eun Mi Hwang et al.   Nature Communications

Dual patch voltage clamp study of low membrane resistance astrocytes in situ

(2014) Baofeng Ma et al.   Molecular Brain

A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels

(2013) Susanne Rinné et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The contribution of TWIK-1 channels to astrocyte K+ current is limited by retention in intracellular compartments

(2013) Wei Wang et al.   Frontiers in Cellular Neuroscience

Silent TWIK-1 Potassium Channels Conduct Monovalent Cation Currents

(2012) Liqun Ma et al.   BIOPHYSICAL JOURNAL

Bicarbonate efflux via GABAA receptors depolarizes membrane potential and inhibits two-pore domain potassium channels of astrocytes in rat hippocampal slices

(2012) Bao-Feng Ma et al.   GLIA

Acid-sensitive TWIK and TASK Two-pore Domain Potassium Channels Change Ion Selectivity and Become Permeable to Sodium in Extracellular Acidification

(2012) Liqun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Astrocytic Glycogen in Supporting the Energetics of Neuronal Activity

(2012) Mauro DiNuzzo et al.   NEUROCHEMICAL RESEARCH

TWIK1, a unique background channel with variable ion selectivity

(2012) F. C. Chatelain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebrovascular responses in mice deficient in the potassium channel, TREK-1

(2010) Khodadad Namiranian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Functions of Mature Mammalian Astrocytes: A Current View

(2010) Harold K. Kimelberg   NEUROSCIENTIST

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS

Potassium Channel Silencing by Constitutive Endocytosis and Intracellular Sequestration

(2009) Sylvain Feliciangeli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TWIK-1 and TREK-1 Are Potassium Channels Contributing Significantly to Astrocyte Passive Conductance in Rat Hippocampal Slices

(2009) M. Zhou et al.   JOURNAL OF NEUROSCIENCE

Analysis of Astroglial K+ Channel Expression in the Developing Hippocampus Reveals a Predominant Role of the Kir4.1 Subunit

(2009) G. Seifert et al.   JOURNAL OF NEUROSCIENCE

Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion

(2008) Tanja Brenner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity

(2008) Tony Kelly et al.   GLIA

Functional implications for Kir4.1 channels in glial biology: from K+buffering to cell differentiation

(2008) Michelle L. Olsen et al.   JOURNAL OF NEUROCHEMISTRY

Mtap2 Is a Constituent of the Protein Network That Regulates Twik-Related K+ Channel Expression and Trafficking

(2008) G. Sandoz et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

The astrocyte odyssey

(2008) D WANG et al.   PROGRESS IN NEUROBIOLOGY

Developmental profile and properties of sulforhodamine 101—Labeled glial cells in acute brain slices of rat hippocampus

(2007) Karl Wolfgang Kafitz et al.   JOURNAL OF NEUROSCIENCE METHODS