Porcine Circovirus 2 Deploys PERK Pathway and GRP78 for Its Enhanced Replication in PK-15 Cells

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UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

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HSPA5 is an essential host factor for Ebola virus infection

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Porcine circovirus-2 capsid protein induces cell death in PK15 cells

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ER stress, autophagy, and RNA viruses

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Correlation of the cyclin A expression level with porcine circovirus type 2 propagation efficiency

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The expanding roles of endoplasmic reticulum stress in virus replication and pathogenesis

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IRE1: ER stress sensor and cell fate executor

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Tick-borne encephalitis virus triggers inositol-requiring enzyme 1 (IRE1) and transcription factor 6 (ATF6) pathways of unfolded protein response

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Porcine Circovirus Type 2 (PCV2): Pathogenesis and Interaction with the Immune System

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Divergent Roles of Autophagy in Virus Infection

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Herpes simplex virus-1 disarms the unfolded protein response in the early stages of infection

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Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

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Porcine Circovirus Type 2 Induces Autophagy via the AMPK/ERK/TSC2/mTOR Signaling Pathway in PK-15 Cells

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The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with cell cycle arrest

(2012) Long-Zhu Li   WORLD JOURNAL OF GASTROENTEROLOGY

Structure–function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells

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Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

Epidemiology and transmission of porcine circovirus type 2 (PCV2)

(2011) Nicolas Rose et al.   VIRUS RESEARCH

Porcine circovirus: Transcription and DNA replication

(2011) Andrew K. Cheung   VIRUS RESEARCH

Porcine circovirus type 2 (PCV2) infections: Clinical signs, pathology and laboratory diagnosis

(2011) Joaquim Segalés   VIRUS RESEARCH

Porcine circovirus type 2 explores the autophagic machinery for replication in PK-15 cells

(2011) Binglin Zhu et al.   VIRUS RESEARCH

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2)

(2011) Nathan M. Beach et al.   VIRUS RESEARCH

Betanodavirus up-regulates chaperone GRP78 via ER stress: roles of GRP78 in viral replication and host mitochondria-mediated cell death

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GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

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Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP

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The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

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