Phleboviruses and the Type I Interferon Response

Phleboviruses associated with sand flies in arid bio-geographical areas of Central Tunisia

(2016) K. Dachraoui et al.   ACTA TROPICA

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

(2016) Cherie T. Ng et al.   CELL

Isolation, full genomic characterization and neutralization-based human seroprevalence of Medjerda Valley virus, a novel sandfly-borne phlebovirus belonging to the Salehabad virus complex in northern Tunisia

(2016) Laurence Bichaud et al.   JOURNAL OF GENERAL VIROLOGY

NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR

(2016) Markus Kainulainen et al.   JOURNAL OF VIROLOGY

Genetic characterization of Arrabida virus, a novel phlebovirus isolated in South Portugal

(2016) Fátima Amaro et al.   VIRUS RESEARCH

Sandfly-Borne Phlebovirus Isolations from Turkey: New Insight into the Sandfly fever Sicilian and Sandfly fever Naples Species

(2016) Cigdem Alkan et al.   PLoS Neglected Tropical Diseases

Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase

(2016) Rajini Mudhasani et al.   PLoS Pathogens

Viral RNA detection by RIG-I-like receptors

(2015) Mitsutoshi Yoneyama et al.   CURRENT OPINION IN IMMUNOLOGY

Intracellular detection of viral nucleic acids

(2015) Konstantin MJ Sparrer et al.   CURRENT OPINION IN MICROBIOLOGY

Bunyaviruses: from transmission by arthropods to virus entry into the mammalian host first-target cells

(2015) Psylvia Léger et al.   Future Virology

Characterization of the Punta Toro species complex (genus Phlebovirus, family Bunyaviridae)

(2015) Gustavo Palacios et al.   JOURNAL OF GENERAL VIROLOGY

Isolation, Genetic Characterization, and Seroprevalence of Adana Virus, a Novel Phlebovirus Belonging to the Salehabad Virus Complex, in Turkey

(2015) Cigdem Alkan et al.   JOURNAL OF VIROLOGY

Generation of Mutant Uukuniemi Viruses Lacking the Nonstructural Protein NSs by Reverse Genetics Indicates that NSs Is a Weak Interferon Antagonist

(2015) Veronica V. Rezelj et al.   JOURNAL OF VIROLOGY

Disruption of Type I Interferon Signaling by the Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Virus via the Hijacking of STAT2 and STAT1 into Inclusion Bodies

(2015) Yun-Jia Ning et al.   JOURNAL OF VIROLOGY

A ΩXaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

(2015) Normand Cyr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mx GTPases: dynamin-like antiviral machines of innate immunity

(2015) Otto Haller et al.   TRENDS IN MICROBIOLOGY

Rift Valley fever virus NSS gene expression correlates with a defect in nuclear mRNA export

(2015) Anna Maria Copeland et al.   VIROLOGY

Truncation of the C-terminal region of Toscana Virus NSs protein is critical for interferon-β antagonism and protein stability

(2015) Gianni Gori Savellini et al.   VIROLOGY

Ubiquitination in the antiviral immune response

(2015) Meredith E. Davis et al.   VIROLOGY

Co-circulation of a novel phlebovirus and Massilia virus in sandflies, Portugal

(2015) Fátima Amaro et al.   Virology Journal

Reverse Genetics System for Severe Fever with Thrombocytopenia Syndrome Virus

(2015) Benjamin Brennan et al.   JOURNAL OF VIROLOGY

Viral Isolates of a Novel Putative Phlebovirus in the Marche Region of Italy

(2014) Maria Elena Remoli et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Segmented negative-strand RNA viruses and RIG-I: divide (your genome) and rule

(2014) Michaela Weber et al.   CURRENT OPINION IN MICROBIOLOGY

RIG-I-like receptors and negative-strand RNA viruses: RLRly bird catches some worms

(2014) Michaela Weber et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Roles of viroplasm-like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus

(2014) Xiaodong Wu et al.   FASEB JOURNAL

Hijacking of RIG-I Signaling Proteins into Virus-Induced Cytoplasmic Structures Correlates with the Inhibition of Type I Interferon Responses

(2014) F. W. Santiago et al.   JOURNAL OF VIROLOGY

Comprehensive Molecular Detection of Tick-Borne Phleboviruses Leads to the Retrospective Identification of Taxonomically Unassigned Bunyaviruses and the Discovery of a Novel Member of the Genus Phlebovirus

(2014) Keita Matsuno et al.   JOURNAL OF VIROLOGY

Virulence Factor NSs of Rift Valley Fever Virus Recruits the F-Box Protein FBXO3 To Degrade Subunit p62 of General Transcription Factor TFIIH

(2014) M. Kainulainen et al.   JOURNAL OF VIROLOGY

Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

(2014) Volker Fensterl et al.   JOURNAL OF VIROLOGY

Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform

(2014) Yun-Jia Ning et al.   Journal of Molecular Cell Biology

Emerging phleboviruses

(2014) Richard M Elliott et al.   Current Opinion in Virology

First Detection of Heartland Virus (Bunyaviridae: Phlebovirus) from Field Collected Arthropods

(2013) Harry M. Savage et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Sandfly-borne phleboviruses of Eurasia and Africa: Epidemiology, genetic diversity, geographic range, control measures

(2013) Cigdem Alkan et al.   ANTIVIRAL RESEARCH

Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling

(2013) Michaela Weber et al.   Cell Host & Microbe

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Master sensors of pathogenic RNA – RIG-I like receptors

(2013) Martin Schlee   IMMUNOBIOLOGY

Is the United States really at risk for introduction of Rift Valley fever virus?

(2013) Mo Salman   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae)

(2013) G. Palacios et al.   JOURNAL OF GENERAL VIROLOGY

The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan

(2013) Toru Takahashi et al.   JOURNAL OF INFECTIOUS DISEASES

Detection of a novel bunyavirus associated with fever, thrombocytopenia and leukopenia syndrome in Henan Province, China, using real-time reverse transcription PCR

(2013) X. Huang et al.   JOURNAL OF MEDICAL MICROBIOLOGY

IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus

(2013) R. Mudhasani et al.   JOURNAL OF VIROLOGY

Characterization of the Uukuniemi Virus Group (Phlebovirus: Bunyaviridae): Evidence for Seven Distinct Species

(2013) G. Palacios et al.   JOURNAL OF VIROLOGY

RNA Helicase Signaling Is Critical for Type I Interferon Production and Protection against Rift Valley Fever Virus during Mucosal Challenge

(2013) M. E. Ermler et al.   JOURNAL OF VIROLOGY

Characterization of the Bhanja Serogroup Viruses (Bunyaviridae): a Novel Species of the Genus Phlebovirus and Its Relationship with Other Emerging Tick-Borne Phleboviruses

(2013) K. Matsuno et al.   JOURNAL OF VIROLOGY

Systems To Establish Bunyavirus Genome Replication in the Absence of Transcription

(2013) C. Klemm et al.   JOURNAL OF VIROLOGY

Evasion of Antiviral Immunity through Sequestering of TBK1/IKK /IRF3 into Viral Inclusion Bodies

(2013) X. Wu et al.   JOURNAL OF VIROLOGY

Toscana Virus NSs Protein Promotes Degradation of Double-Stranded RNA-Dependent Protein Kinase

(2013) B. Kalveram et al.   JOURNAL OF VIROLOGY

Toscana Virus NSs Protein Inhibits the Induction of Type I Interferon by Interacting with RIG-I

(2013) G. Gori-Savellini et al.   JOURNAL OF VIROLOGY

Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus

(2013) F. Zielecki et al.   JOURNAL OF VIROLOGY

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

(2013) John W. Schoggins et al.   NATURE

Identification of Novel Viruses Using VirusHunter -- an Automated Data Analysis Pipeline

(2013) Guoyan Zhao et al.   PLoS One

Toscana virus inhibits the interferon beta response in cell cultures

(2013) Nadege M. Brisbarre et al.   VIROLOGY

Characterization of Rift Valley Fever Virus MP-12 Strain Encoding NSs of Punta Toro Virus or Sandfly Fever Sicilian Virus

(2013) Olga A. Lihoradova et al.   PLoS Neglected Tropical Diseases

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

(2013) Siqi Liu et al.   eLife

The risk of Rift Valley fever virus introduction and establishment in the United States and European Union

(2013) Alicia I Rolin et al.   Emerging Microbes & Infections

A case of central nervous system infection due to a novel Sandfly Fever Virus (SFV) variant: Sandfly Fever Turkey Virus (SFTV)

(2012) Koray Ergunay et al.   JOURNAL OF CLINICAL VIROLOGY

Characterization of the Salehabad virus species complex of the genus Phlebovirus (Bunyaviridae)

(2012) G. Palacios et al.   JOURNAL OF GENERAL VIROLOGY

New PARP Gene with an Anti-Alphavirus Function

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

Suppression of the Interferon and NF-κB Responses by Severe Fever with Thrombocytopenia Syndrome Virus

(2012) Bingqian Qu et al.   JOURNAL OF VIROLOGY

Viral immune modulators perturb the human molecular network by common and unique strategies

(2012) Andreas Pichlmair et al.   NATURE

A New Phlebovirus Associated with Severe Febrile Illness in Missouri

(2012) Laura K. McMullan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic characterization of Bhanja virus and Palma virus, two tick-borne phleboviruses

(2012) Meik Dilcher et al.   VIRUS GENES

DC-SIGN as a Receptor for Phleboviruses

(2011) Pierre-Yves Lozach et al.   Cell Host & Microbe

Aguacate virus, a new antigenic complex of the genus Phlebovirus (family Bunyaviridae)

(2011) G. Palacios et al.   JOURNAL OF GENERAL VIROLOGY

Recent advances in the molecular and cellular biology of bunyaviruses

(2011) C. T. Walter et al.   JOURNAL OF GENERAL VIROLOGY

Clinical and laboratory findings of a sandfly fever Turkey Virus outbreak in Ankara

(2011) Zeliha Kocak Tufan et al.   JOURNAL OF INFECTION

Characterization of the Candiru Antigenic Complex (Bunyaviridae: Phlebovirus), a Highly Diverse and Reassorting Group of Viruses Affecting Humans in Tropical America

(2011) G. Palacios et al.   JOURNAL OF VIROLOGY

Rift Valley Fever: Recent Insights into Pathogenesis and Prevention

(2011) H. Boshra et al.   JOURNAL OF VIROLOGY

Rift Valley Fever Virus Vaccine Lacking the NSs and NSm Genes Is Safe, Nonteratogenic, and Confers Protection from Viremia, Pyrexia, and Abortion following Challenge in Adult and Pregnant Sheep

(2011) B. H. Bird et al.   JOURNAL OF VIROLOGY

Characterization of Wild-Type and Alternate Transcription Termination Signals in the Rift Valley Fever Virus Genome

(2011) E. Lara et al.   JOURNAL OF VIROLOGY

NSs Protein of Rift Valley Fever Virus Promotes Posttranslational Downregulation of the TFIIH Subunit p62

(2011) B. Kalveram et al.   JOURNAL OF VIROLOGY

The Ecology, Genetic Diversity, and Phylogeny of Huaiyangshan Virus in China

(2011) Y.-Z. Zhang et al.   JOURNAL OF VIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Fever with Thrombocytopenia Associated with a Novel Bunyavirus in China

(2011) Xue-Jie Yu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metagenomic Analysis of Fever, Thrombocytopenia and Leukopenia Syndrome (FTLS) in Henan Province, China: Discovery of a New Bunyavirus

(2011) Bianli Xu et al.   PLoS Pathogens

Granada Virus: a Natural Phlebovirus Reassortant of the Sandfly Fever Naples Serocomplex with Low Seroprevalence in Humans

(2010) Ximena Collao et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Entry of Bunyaviruses into Mammalian Cells

(2010) Pierre-Yves Lozach et al.   Cell Host & Microbe

Characterization of a sandfly fever Sicilian virus isolated during a sandfly fever epidemic in Turkey

(2010) Ahmet Çarhan et al.   JOURNAL OF CLINICAL VIROLOGY

Punique virus, a novel phlebovirus, related to sandfly fever Naples virus, isolated from sandflies collected in Tunisia

(2010) E. Zhioua et al.   JOURNAL OF GENERAL VIROLOGY

Toscana virus induces interferon although its NSs protein reveals antagonistic activity

(2010) G. Gori Savellini et al.   JOURNAL OF GENERAL VIROLOGY

A New Mouse Model Reveals a Critical Role for Host Innate Immunity in Resistance to Rift Valley Fever

(2010) T. Z. do Valle et al.   JOURNAL OF IMMUNOLOGY

The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription

(2010) Benjamin Morin et al.   PLoS Pathogens

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Rift Valley fever virus

(2009) Brian H. Bird et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Electron Cryo-Microscopy and Single-Particle Averaging of Rift Valley Fever Virus: Evidence for GN-GC Glycoprotein Heterodimers

(2009) J. T. Huiskonen et al.   JOURNAL OF VIROLOGY

NSs Protein of Rift Valley Fever Virus Induces the Specific Degradation of the Double-Stranded RNA-Dependent Protein Kinase

(2009) M. Habjan et al.   JOURNAL OF VIROLOGY

Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection

(2009) A. Pichlmair et al.   JOURNAL OF VIROLOGY

Punta Toro virus (Bunyaviridae, Phlebovirus) infection in mice: Strain differences in pathogenesis and host interferon response

(2009) Michelle Mendenhall et al.   VIROLOGY

Efficient production of Rift Valley fever virus-like particles: The antiviral protein MxA can inhibit primary transcription of bunyaviruses

(2009) Matthias Habjan et al.   VIROLOGY

Rift Valley Fever Virus NSs Protein Promotes Post-Transcriptional Downregulation of Protein Kinase PKR and Inhibits eIF2α Phosphorylation

(2009) Tetsuro Ikegami et al.   PLoS Pathogens

T7 RNA polymerase-dependent and -independent systems for cDNA-based rescue of Rift Valley fever virus

(2008) M. Habjan et al.   JOURNAL OF GENERAL VIROLOGY

Rift Valley Fever Virus Lacking the NSs and NSm Genes Is Highly Attenuated, Confers Protective Immunity from Virulent Virus Challenge, and Allows for Differential Identification of Infected and Vaccinated Animals

(2008) B. H. Bird et al.   JOURNAL OF VIROLOGY

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

(2008) Matthias Habjan et al.   PLoS One

A SAP30 Complex Inhibits IFN-β Expression in Rift Valley Fever Virus Infected Cells

(2008) Nicolas Le May et al.   PLoS Pathogens

Insights into bunyavirus architecture from electron cryotomography of Uukuniemi virus

(2008) A. K. Overby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Massilia Virus, A Novel Phlebovirus (Bunyaviridae) Isolated from Sandflies in the Mediterranean

(2008) Rémi N. Charrel et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

RNA polymerase I-mediated expression of viral RNA for the rescue of infectious virulent and avirulent Rift Valley fever viruses

(2008) Agnès Billecocq et al.   VIROLOGY