Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host Immunity

Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein

(2016) Junsong Zhang et al.   JOURNAL OF VIROLOGY

Discovery of novel targets for antivirals: learning from flies

(2016) Nelson Martins et al.   Current Opinion in Virology

Viruses Utilize Cellular Cues in Distinct Combination to Undergo Systematic Priming and Uncoating

(2016) Madhu Sudhan Ravindran et al.   PLoS Pathogens

Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import

(2016) Veronika Götz et al.   Scientific Reports

Fluorescence Tracking of Genome Release during Mechanical Unpacking of Single Viruses

(2015) Alvaro Ortega-Esteban et al.   ACS Nano

Mechanics of Viral Chromatin Reveals the Pressurization of Human Adenovirus

(2015) Alvaro Ortega-Esteban et al.   ACS Nano

Co-option of Membrane Wounding Enables Virus Penetration into Cells

(2015) Stefania Luisoni et al.   Cell Host & Microbe

A Single Maturation Cleavage Site in Adenovirus Impacts Cell Entry and Capsid Assembly

(2015) Crystal L. Moyer et al.   JOURNAL OF VIROLOGY

Distribution of DNA-condensing protein complexes in the adenovirus core

(2015) Ana J. Pérez-Berná et al.   NUCLEIC ACIDS RESEARCH

Residue-level resolution of alphavirus envelope protein interactions in pH-dependent fusion

(2015) Xiancheng Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA virus uncoating

(2015) Samuel Kilcher et al.   VIROLOGY

Adenovirus Composition, Proteolysis, and Disassembly Studied by In-depth Qualitative and Quantitative Proteomics

(2014) Marco Benevento et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKA-dependent dynein switching from lysosomes to adenovirus: A novel form of host–virus competition

(2014) Julian Scherer et al.   JOURNAL OF CELL BIOLOGY

The Cleaved N-Terminus of pVI Binds Peripentonal Hexons in Mature Adenovirus

(2014) Joost Snijder et al.   JOURNAL OF MOLECULAR BIOLOGY

pH-Induced Stability Switching of the Bacteriophage HK97 Maturation Pathway

(2014) Eric R. May et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational Changes in the Adenovirus Hexon Subunit Responsible for Regulating Cytoplasmic Dynein Recruitment

(2014) Julian Scherer et al.   JOURNAL OF VIROLOGY

Nuclear Import of Adenovirus DNA Involves Direct Interaction of Hexon with an N-Terminal Domain of the Nucleoporin Nup214

(2014) Aurélia Cassany et al.   JOURNAL OF VIROLOGY

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

(2014) Akash Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures and organization of adenovirus cement proteins provide insights into the role of capsid maturation in virus entry and infection

(2014) V. S. Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delineation of Interfaces on Human Alpha-Defensins Critical for Human Adenovirus and Human Papillomavirus Inhibition

(2014) Victoria R. Tenge et al.   PLoS Pathogens

A Direct and Versatile Assay Measuring Membrane Penetration of Adenovirus in Single Cells

(2013) M. Suomalainen et al.   JOURNAL OF VIROLOGY

An Intrinsically Disordered Region of the Adenovirus Capsid Is Implicated in Neutralization by Human Alpha Defensin 5

(2013) Justin W. Flatt et al.   PLoS One

Monitoring dynamics of human adenovirus disassembly induced by mechanical fatigue

(2013) A. Ortega-Esteban et al.   Scientific Reports

The Spatial Organization of DNA Virus Genomes in the Nucleus

(2013) Roger D. Everett   PLoS Pathogens

Critical Determinants of Human α-Defensin 5 Activity against Non-enveloped Viruses

(2012) Anshu P. Gounder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Capsid Maturation on Adenovirus Priming for Sequential Uncoating

(2012) Ana J. Pérez-Berná et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of a Viral Proteinase by a Peptide and DNA in One-dimensional Space

(2012) Paul C. Blainey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved Fiber-Penton Base Interaction Revealed by Nearly Atomic Resolution Cryo-Electron Microscopy of the Structure of Adenovirus Provides Insight into Receptor Interaction

(2012) C. Cao et al.   JOURNAL OF VIROLOGY

Integrin and Defensin Modulate the Mechanical Properties of Adenovirus

(2012) J. Snijder et al.   JOURNAL OF VIROLOGY

Kinesin-1-Mediated Capsid Disassembly and Disruption of the Nuclear Pore Complex Promote Virus Infection

(2011) Sten Strunze et al.   Cell Host & Microbe

Drifting Motions of the Adenovirus Receptor CAR and Immobile Integrins Initiate Virus Uncoating and Membrane Lytic Protein Exposure

(2011) Christoph J. Burckhardt et al.   Cell Host & Microbe

Functional Genetic and Biophysical Analyses of Membrane Disruption by Human Adenovirus

(2011) C. L. Moyer et al.   JOURNAL OF VIROLOGY

Model of the Trimeric Fiber and Its Interactions with the Pentameric Penton Base of Human Adenovirus by Cryo-electron Microscopy

(2010) Hongrong Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Evidence from Single-Cell Analysis that Human  -Defensins Block Adenovirus Uncoating To Neutralize Infection

(2010) E. K. Nguyen et al.   JOURNAL OF VIROLOGY

Structure of Adenovirus Type 21 Knob in Complex with CD46 Reveals Key Differences in Receptor Contacts among Species B Adenoviruses

(2010) K. Cupelli et al.   JOURNAL OF VIROLOGY

Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14

(2010) Hongjie Wang et al.   NATURE MEDICINE

The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis

(2010) Emma C Nilsson et al.   NATURE MEDICINE

Crystal Structure of Human Adenovirus at 3.5 A Resolution

(2010) V. S. Reddy et al.   SCIENCE

Atomic Structure of Human Adenovirus by Cryo-EM Reveals Interactions Among Protein Networks

(2010) H. Liu et al.   SCIENCE

Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

(2010) Jason G. Smith et al.   PLoS Pathogens

A Capsid-Encoded PPxY-Motif Facilitates Adenovirus Entry

(2010) Harald Wodrich et al.   PLoS Pathogens

Structure of the Extracellular Portion of CD46 Provides Insights into Its Interactions with Complement Proteins and Pathogens

(2010) B. David Persson et al.   PLoS Pathogens

Adenovirus Transport via Direct Interaction of Cytoplasmic Dynein with the Viral Capsid Hexon Subunit

(2009) K. Helen Bremner et al.   Cell Host & Microbe

Structure and Uncoating of Immature Adenovirus

(2009) Ana J. Pérez-Berná et al.   JOURNAL OF MOLECULAR BIOLOGY

Cryo-Electron Microscopy Structure of Adenovirus Type 2 Temperature-Sensitive Mutant 1 Reveals Insight into the Cell Entry Defect

(2009) M. Silvestry et al.   JOURNAL OF VIROLOGY

Cryo-Electron Microscopy Structure of an Adenovirus-Integrin Complex Indicates Conformational Changes in both Penton Base and Integrin

(2009) S. Lindert et al.   JOURNAL OF VIROLOGY

Molecular dynamics flexible fitting: A practical guide to combine cryo-electron microscopy and X-ray crystallography

(2009) Leonardo G. Trabuco et al.   METHODS

Scaffold expulsion and genome packaging trigger stabilization of herpes simplex virus capsids

(2009) W. H. Roos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic reconstitution of the human Adenovirus type 2 temperature-sensitive 1 mutant defective in endosomal escape

(2009) Nicola Imelli et al.   Virology Journal

A Stochastic Model for Microtubule Motors Describes the In Vivo Cytoplasmic Transport of Human Adenovirus

(2009) Mattia Gazzola et al.   PLoS Computational Biology

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

(2009) Elena Seiradake et al.   PLoS Pathogens

Mechanism of Adenovirus Neutralization by Human α-Defensins

(2008) Jason G. Smith et al.   Cell Host & Microbe

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE

Insights into adenovirus host cell interactions from structural studies

(2008) G.R. Nemerow et al.   VIROLOGY