An Intrinsically Disordered Region of the Adenovirus Capsid Is Implicated in Neutralization by Human Alpha Defensin 5

Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method

(2012) Kwok-Yan Chan et al.   BIOPOLYMERS

Critical Determinants of Human α-Defensin 5 Activity against Non-enveloped Viruses

(2012) Anshu P. Gounder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multifaceted Mechanisms of HIV-1 Entry Inhibition by Human α-Defensin

(2012) Lusine H. Demirkhanyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Determinants of Human Enteric α-Defensin HD5

(2012) Mohsen Rajabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CryoEM Visualization of an Adenovirus Capsid-Incorporated HIV Antigen

(2012) Justin W. Flatt et al.   PLoS One

Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus

(2012) K. Doronin et al.   SCIENCE

Human  -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

(2012) H. Chu et al.   SCIENCE

α-Defensins in human innate immunity

(2011) Robert I. Lehrer et al.   IMMUNOLOGICAL REVIEWS

Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation

(2011) Miriam Wilmes et al.   NATURAL PRODUCT REPORTS

Viral weapons of membrane destruction: variable modes of membrane penetration by non-enveloped viruses

(2011) Crystal L Moyer et al.   Current Opinion in Virology

The Membrane-Bound Structure and Topology of a Human α-Defensin Indicate a Dimer Pore Mechanism for Membrane Disruption

(2010) Yuan Zhang et al.   BIOCHEMISTRY

Host defense peptides and their antimicrobial-immunomodulatory duality

(2010) Lars Steinstraesser et al.   IMMUNOBIOLOGY

Resonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMR

(2010) Yuan Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Evidence from Single-Cell Analysis that Human  -Defensins Block Adenovirus Uncoating To Neutralize Infection

(2010) E. K. Nguyen et al.   JOURNAL OF VIROLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Crystal Structure of Human Adenovirus at 3.5 A Resolution

(2010) V. S. Reddy et al.   SCIENCE

Atomic Structure of Human Adenovirus by Cryo-EM Reveals Interactions Among Protein Networks

(2010) H. Liu et al.   SCIENCE

Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

(2010) Jason G. Smith et al.   PLoS Pathogens

Cryo-Electron Microscopy Structure of an Adenovirus-Integrin Complex Indicates Conformational Changes in both Penton Base and Integrin

(2009) S. Lindert et al.   JOURNAL OF VIROLOGY

Molecular dynamics flexible fitting: A practical guide to combine cryo-electron microscopy and X-ray crystallography

(2009) Leonardo G. Trabuco et al.   METHODS

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Mechanism of Adenovirus Neutralization by Human α-Defensins

(2008) Jason G. Smith et al.   Cell Host & Microbe

Human α-Defensins Inhibit BK Virus Infection by Aggregating Virions and Blocking Binding to Host Cells

(2008) Aisling S. Dugan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE