T-bet expression in CD8+ T cells associated with chronic hepatitis B virus infection

Dysfunctional CD8+T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction

(2014) Peter D. Kurktschiev et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Management of chronic hepatitis B in children: An unresolved issue

(2014) Claudia Della Corte et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

IL-21 Promotes CD8+ CTL Activity via the Transcription Factor T-bet

(2013) A. P. R. Sutherland et al.   JOURNAL OF IMMUNOLOGY

The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells

(2013) Anna Schurich et al.   PLoS Pathogens

Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells

(2012) C. Smith et al.   BLOOD

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors

(2012) P. Ribeiro-dos-Santos et al.   BLOOD

Preserved T-Cell Function in Children and Young Adults With Immune-Tolerant Chronic Hepatitis B

(2012) Patrick T.F. Kennedy et al.   GASTROENTEROLOGY

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

(2012) M. A. Paley et al.   SCIENCE

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

(2011) A. R. Hersperger et al.   BLOOD

T-bet in disease

(2011) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection

(2011) Charlly Kao et al.   NATURE IMMUNOLOGY

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

T-bet and Eomesodermin Are Required for T Cell-Mediated Antitumor Immune Responses

(2010) Y. Zhu et al.   JOURNAL OF IMMUNOLOGY

Redefining Chronic Viral Infection

(2009) Herbert W. Virgin et al.   CELL

Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients

(2009) Zheng Zhang et al.   JOURNAL OF HEPATOLOGY

Hepatitis B virus infection

(2009) Yun-Fan Liaw et al.   LANCET