Highly activated p53 contributes to selectively increased apoptosis of latently HIV-1 infected cells upon treatment of anticancer drugs

p53-Derived Host Restriction of HIV-1 Replication by Protein Kinase R-Mediated Tat Phosphorylation and Inactivation

(2015) Cheol-Hee Yoon et al.   JOURNAL OF VIROLOGY

Apoptosis-induced activation of HIV-1 in latently infected cell lines

(2015) Sohrab Z. Khan et al.   Retrovirology

Genotoxic Anti-Cancer Agents and Their Relationship to DNA Damage, Mitosis, and Checkpoint Adaptation in Proliferating Cancer Cells

(2014) Lucy Swift et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent developments in the search for a cure for HIV-1 infection: Targeting the latent reservoir for HIV-1

(2014) Janet D. Siliciano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NUCKS1, a novel Tat coactivator, plays a crucial role in HIV-1 replication by increasing Tat-mediated viral transcription on the HIV-1 LTR promoter

(2014) Hye-Young Kim et al.   Retrovirology

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration

(2013) Arik Cooper et al.   NATURE

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Autophagy Inhibition Promotes 5-Fluorouraci-Induced Apoptosis by Stimulating ROS Formation in Human Non-Small Cell Lung Cancer A549 Cells

(2013) Xiaohong Pan et al.   PLoS One

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

Eliminating the latent HIV reservoir by reactivation strategies: Advancing to clinical trials

(2013) Thomas Rasmussen et al.   Human Vaccines & Immunotherapeutics

Gamma radiation alters cell cycle and induces apoptosis in p53 mutant E6.1 Jurkat cells

(2012) Mohammad Reza Ahmadianpour et al.   APPLIED RADIATION AND ISOTOPES

Targeting HIV latency: pharmacologic strategies toward eradication

(2012) Sifei Xing et al.   DRUG DISCOVERY TODAY

5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress

(2012) Monica Lamberti et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inhibition of  -TrcP-dependent ubiquitination of p53 by HIV-1 Vpu promotes p53-mediated apoptosis in human T cells

(2011) S. Verma et al.   BLOOD

CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

(2011) Michèle Février et al.   Viruses-Basel

The effect of CD4 receptor downregulation and its downstream signaling molecules on HIV-1 latency

(2010) Kyung-Chang Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TLR3 induction by anticancer drugs potentiates poly I:C-induced tumor cell apoptosis

(2010) Manabu Taura et al.   CANCER SCIENCE

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

(2009) Mayte Coiras et al.   NATURE REVIEWS MICROBIOLOGY

PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53

(2009) C.-H. Yoon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells

(2009) Michaël Imbeault et al.   Retrovirology

Efficient magnetic bead-based separation of HIV-1-infected cells using an improved reporter virus system reveals that p53 up-regulation occurs exclusively in the virus-expressing cell population

(2009) Michaël Imbeault et al.   VIROLOGY

The dark side of a tumor suppressor: anti-apoptotic p53

(2008) R U Jänicke et al.   CELL DEATH AND DIFFERENTIATION

Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway

(2008) Pablo N Fernández Larrosa et al.   Retrovirology