In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in situ hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgrading
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Title
In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in situ hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgrading
Authors
Keywords
Gleason upgrade, Tumor suppressor gene, Prognostic biomarker assay, Hemizygous and homozygous genomic deletion
Journal
VIRCHOWS ARCHIV
Volume 468, Issue 5, Pages 607-617
Publisher
Springer Nature
Online
2016-02-09
DOI
10.1007/s00428-016-1904-2
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