Dentin Dysplasia in Notum Knockout Mice

Temporo-spatial requirement of Smad4 in dentin formation

(2015) Tak-Heun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lhx8 mediated Wnt and TGFβ pathways in tooth development and regeneration

(2015) Chen Zhou et al.   BIOMATERIALS

Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation

(2015) Xinjun Zhang et al.   DEVELOPMENTAL CELL

Notum deacylates Wnt proteins to suppress signalling activity

(2015) Satoshi Kakugawa et al.   NATURE

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

The non-canonical BMP and Wnt/ -catenin signaling pathways orchestrate early tooth development

(2014) G. Yuan et al.   DEVELOPMENT

Glial origin of mesenchymal stem cells in a tooth model system

(2014) Nina Kaukua et al.   NATURE

Wnt5a Is Necessary for Normal Kidney Development in Zebrafish and Mice

(2014) Liwei Huang et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity

(2014) Konstantin V. Salojin et al.   PLoS One

Malformation of Incisor Teeth in Grem2-/- Mice

(2014) P. Vogel et al.   VETERINARY PATHOLOGY

Nephronophthisis and Retinal Degeneration in Tmem218–/– Mice

(2014) P. Vogel et al.   VETERINARY PATHOLOGY

Wnt signaling: Role in LTP, neural networks and memory

(2013) Carolina A. Oliva et al.   AGEING RESEARCH REVIEWS

Secretion and extracellular space travel of Wnt proteins

(2013) Julia Christina Gross et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Disruption of Wnt/β-catenin Signaling in Odontoblasts and Cementoblasts Arrests Tooth Root Development in Postnatal Mouse Teeth

(2013) Ran Zhang et al.   International Journal of Biological Sciences

Intra-epithelial Requirement of Canonical Wnt Signaling for Tooth Morphogenesis

(2013) XiaoJing Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt Signaling Regulates Pulp Volume and Dentin Thickness

(2013) Won Hee Lim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

A zebrafish Notum homolog specifically blocks the Wnt/ -catenin signaling pathway

(2012) G. P. Flowers et al.   DEVELOPMENT

Three decades of Wnts: a personal perspective on how a scientific field developed

(2012) Roel Nusse et al.   EMBO JOURNAL

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

(2012) Nibaldo C. Inestrosa et al.   Journal of Neuroimmune Pharmacology

Excessive Wnt/β-catenin signaling disturbs tooth-root formation

(2012) C. H. Bae et al.   JOURNAL OF PERIODONTAL RESEARCH

Amelogenesis Imperfecta and Other Biomineralization Defects in Fam20a and Fam20c Null Mice

(2012) P. Vogel et al.   VETERINARY PATHOLOGY

Alternative Wnt Pathways and Receptors

(2012) R. van Amerongen   Cold Spring Harbor Perspectives in Biology

Wnt Signaling in Cancer

(2012) P. Polakis   Cold Spring Harbor Perspectives in Biology

Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation

(2011) Tak-Heun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency

(2011) K. V. Salojin et al.   BLOOD

SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis

(2011) J. Li et al.   DEVELOPMENT

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice

(2011) P. N. Schofield et al.   Disease Models & Mechanisms

 -Catenin Causes Renal Dysplasia via Upregulation of Tgf 2 and Dkk1

(2011) D. Bridgewater et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

(2011) C. P. Petersen et al.   SCIENCE

Cardiomyopathy in α-Kinase 3 (ALPK3)–Deficient Mice

(2011) I. Van Sligtenhorst et al.   VETERINARY PATHOLOGY

Congenital Hydrocephalus in Genetically Engineered Mice

(2011) P. Vogel et al.   VETERINARY PATHOLOGY

LRP4 Mutations Alter Wnt/β-Catenin Signaling and Cause Limb and Kidney Malformations in Cenani-Lenz Syndrome

(2010) Yun Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mouse models of tooth abnormalities

(2010) Jana Fleischmannova et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Wnt/β-catenin Signaling in Oral Tissue Development and Disease

(2010) F. Liu et al.   JOURNAL OF DENTAL RESEARCH

Requirement for Class II Phosphoinositide 3-Kinase C2  in Maintenance of Glomerular Structure and Function

(2010) D. P. Harris et al.   MOLECULAR AND CELLULAR BIOLOGY

Profound Obesity Secondary to Hyperphagia in Mice Lacking Kinase Suppressor of Ras 2

(2010) Jean-Pierre Revelli et al.   Obesity

Lrp4 Regulates Initiation of Ureteric Budding and Is Crucial for Kidney Formation – A Mouse Model for Cenani-Lenz Syndrome

(2010) Courtney M. Karner et al.   PLoS One

Regulators of the Proteasome Pathway, Uch37 and Rpn13, Play Distinct Roles in Mouse Development

(2010) Amin Al-Shami et al.   PLoS One

An Alternative Splicing Variant in Clcn7–/– Mice Prevents Osteopetrosis but Not Neural and Retinal Degeneration

(2010) I. Rajan et al.   VETERINARY PATHOLOGY

Tubulin Tyrosine Ligase–Like 1 Deficiency Results in Chronic Rhinosinusitis and Abnormal Development of Spermatid Flagella in Mice

(2010) P. Vogel et al.   VETERINARY PATHOLOGY

Histopathological and Neurological Features of Atg4b Knockout Mice

(2010) R. Read et al.   VETERINARY PATHOLOGY

Pathology of Congenital Generalized Lipodystrophy in Agpat2–/– Mice

(2010) P. Vogel et al.   VETERINARY PATHOLOGY

Situs Inversus in Dpcd/Poll–/–, Nme7–/–, and Pkd1l1–/– Mice

(2010) P. Vogel et al.   VETERINARY PATHOLOGY

Wnt signaling in kidney development and disease

(2010) Kaisa Pulkkinen et al.   Organogenesis

Current knowledge of tooth development: patterning and mineralization of the murine dentition

(2009) Javier Catón et al.   JOURNAL OF ANATOMY

Runx2, Osx, and Dspp in Tooth Development

(2009) S. Chen et al.   JOURNAL OF DENTAL RESEARCH

Emerging roles of Wnts in the adult nervous system

(2009) Nibaldo C. Inestrosa et al.   NATURE REVIEWS NEUROSCIENCE

Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

(2009) Peter Vogel et al.   PLoS One

Lrp4, a Novel Receptor for Dickkopf 1 and Sclerostin, Is Expressed by Osteoblasts and Regulates Bone Growth and Turnover In Vivo

(2009) Hong Y. Choi et al.   PLoS One

Ectonucleoside Triphosphate Diphosphohydrolase Type 5 (Entpd5)-Deficient Mice Develop Progressive Hepatopathy, Hepatocellular Tumors, and Spermatogenic Arrest

(2009) R. Read et al.   VETERINARY PATHOLOGY

Comparative Pathology of Murine Mucolipidosis Types II and IIIC

(2009) P. Vogel et al.   VETERINARY PATHOLOGY

Inhibition of the terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice

(2008) Toshihiro Miyazaki et al.   ARCHIVES OF HISTOLOGY AND CYTOLOGY

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β-catenin/TCF

(2008) Yuichi Torisu et al.   CANCER SCIENCE

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

(2008) G. M. Hansen et al.   GENOME RESEARCH

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

(2008) Q. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia

(2008) Martin J Barron et al.   Orphanet Journal of Rare Diseases

Lrp4 Modulates Extracellular Integration of Cell Signaling Pathways in Development

(2008) Atsushi Ohazama et al.   PLoS One

Ocular Albinism and Hypopigmentation Defects in Slc24a5—I— Mice

(2008) P. Vogel et al.   VETERINARY PATHOLOGY

Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis

(2007) Fei Liu et al.   DEVELOPMENTAL BIOLOGY

Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness

(2007) W. Zhang et al.   GENES BRAIN AND BEHAVIOR