Amelogenesis Imperfecta and Other Biomineralization Defects in Fam20a and Fam20c Null Mice

Tooth dentin defects reflect genetic disorders affecting bone mineralization

(2012) S. Opsahl Vital et al.   BONE

Regulation of Bone−Renal Mineral and Energy Metabolism: The PHEX, FGF23, DMP1, MEPE ASARM Pathway

(2012) Peter S. N. Rowe   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice

(2012) Neil Charles Wallace Mackenzie et al.   PLoS One

Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization

(2012) V. S. Tagliabracci et al.   SCIENCE

Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice

(2012) Xiaofang Wang et al.   PLoS Genetics

Whole-Exome Sequencing Identifies FAM20A Mutations as a Cause of Amelogenesis Imperfecta and Gingival Hyperplasia Syndrome

(2011) James O'Sullivan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle

(2011) Ricardo Villa-Bellosta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice

(2011) P. N. Schofield et al.   Disease Models & Mechanisms

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

(2011) Aline Martin et al.   FASEB JOURNAL

Effect of Kallikrein 4 Loss on Enamel Mineralization

(2011) Charles E. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Daily peritoneal administration of sodium pyrophosphate in a dialysis solution prevents the development of vascular calcification in a mouse model of uraemia

(2011) B. L. Riser et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mutations in fam20b and xylt1 Reveal That Cartilage Matrix Controls Timing of Endochondral Ossification by Inhibiting Chondrocyte Maturation

(2011) B. Frank Eames et al.   PLoS Genetics

Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets

(2010) Bettina Lorenz-Depiereux et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Physiological role of alkaline phosphatase explored in hypophosphatasia

(2010) Michael P. Whyte   Annals of the New York Academy of Sciences

Defining a New Candidate Gene for Amelogenesis Imperfecta: From Molecular Genetics to Biochemistry

(2010) Blanca Urzúa et al.   BIOCHEMICAL GENETICS

Osteosclerotic bone dysplasia in siblings with a Fam20C mutation

(2010) M Fradin et al.   CLINICAL GENETICS

Molecular determinants of extracellular matrix mineralization in bone and blood vessels

(2010) Monzur Murshed et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Autosomal Recessive Mental Retardation, Deafness, Ankylosis, and Mild Hypophosphatemia Associated with a NovelANKHMutation in a Consanguineous Family

(2010) Eva Morava et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse

(2010) Xiaofang Wang et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Hereditary disorders of renal phosphate wasting

(2010) Amir S. Alizadeh Naderi et al.   Nature Reviews Nephrology

FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan–protein linkage region

(2009) Toshiyasu Koike et al.   BIOCHEMICAL JOURNAL

Mutations in FAM20C also identified in non-lethal osteosclerotic bone dysplasia

(2009) MA Simpson et al.   CLINICAL GENETICS

PHEX, FGF23, DMP1 and beyond

(2009) Tim M Strom et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Consequences for enamel development and mineralization resulting from loss of function of ameloblastin or enamelin

(2009) Charles E. Smith et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Hypomaturation Enamel Defects inKlk4Knockout/LacZKnockin Mice

(2009) James P. Simmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mouse model expressing a truncated form of ameloblastin exhibits dental and junctional epithelium defects

(2009) Rima M. Wazen et al.   MATRIX BIOLOGY

Functions of KLK4 and MMP-20 in dental enamel formation

(2008) Yuhe Lu et al.   BIOLOGICAL CHEMISTRY

Phosphate: Known and potential roles during development and regeneration of teeth and supporting structures

(2008) Brian L. Foster et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

(2008) G. M. Hansen et al.   GENOME RESEARCH

Enamel Defects and Ameloblast-specific Expression inEnamKnock-out/lacZKnock-in Mice

(2008) Jan C.-C. Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ocular Albinism and Hypopigmentation Defects in Slc24a5—I— Mice

(2008) P. Vogel et al.   VETERINARY PATHOLOGY